Review
Ophthalmology
Amar Pujari, Gunjan Saluja, Divya Agarwal, Harathy Selvan, Namrata Sharma
Summary: There is a wide variety of imaging devices in ophthalmology, and the potential benefits of using smartphones for detailed, high-quality imaging of various eye structures are continuously being explored. Collaborating with medical experts, smartphone companies can contribute to better serving and helping people in the field of ophthalmic care.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2021)
Article
Clinical Neurology
George He, Hamish P. Dunn, Kate E. Ahmad, Eloise Watson, Andrew Henderson, Dominique Tynan, John Leaney, Andrew J. White, Alex W. Hewitt, Clare L. Fraser
Summary: This study reveals a clinically significant prevalence of fundus pathology among neurology inpatients which is often overlooked by current fundoscopy practices. Portable NMFP screening appears to be more accurate than SF, with both being diagnostically superior to routine fundoscopic practice, feasible, and well tolerated by patients.
EUROPEAN JOURNAL OF NEUROLOGY
(2022)
Article
Ophthalmology
Tyson N. Kim, Michael T. Aaberg, Patrick Li, Jose R. Davila, Malavika Bhaskaranand, Sandeep Bhat, Chaithanya Ramachandra, Kaushal Solanki, Frankie Myers, Clay Reber, Rohan Jalalizadeh, Todd P. Margolis, Daniel Fletcher, Yannis M. Paulus
Summary: The study aimed to investigate the efficacy of a mobile platform combining smartphone-based retinal imaging with automated grading for determining the presence of referral-warranted diabetic retinopathy. Results showed that automated interpretation achieved a lower sensitivity but higher specificity than trained expert graders, indicating potential for improved efficiency in clinical practice. Feasibility testing with non-ophthalmic personnel in a retina clinic with high disease burden suggested further studies are needed to assess efficacy of screening diabetic patients from general population.
Article
Clinical Neurology
Stephen W. English, Kevin M. Barrett, William D. Freeman, Bart M. Demaerschalk, Oana M. Dumitrascu
Summary: This article discusses the importance of diagnosing and managing acute vision loss, highlighting the limitations of remote healthcare services and the impact of the COVID-19 pandemic on ophthalmological diagnosis. The authors propose new approaches to improve remote ophthalmological evaluation and enhance acute ophthalmological care.
Article
Biochemistry & Molecular Biology
James McDonald, Helene Paradis, Michael Bartellas, Robert L. Gendron
Summary: The study aims to enhance the functionality and precision of ophthalmic imaging tools using 3D printing technology, allowing for manual control with a customized assembly and precision control through the rodent stage of the SD-OCT instrument.
Article
Biochemistry & Molecular Biology
Patrick Ferreira, Altino Branco Choupina
Summary: In recent years, the number of tools and techniques for precise genome editing has increased significantly. The CRISPR/Cas9 technology has gained much attention due to its simplicity, affordability, and effectiveness. It has the potential for various applications in gene editing, including functional genomics, cell model development, targeted therapies, and improvement of agricultural and environmental species.
MOLECULAR BIOLOGY REPORTS
(2022)
Article
Ophthalmology
Deniz Oncel, Giulia Corradetti, Yu Wakatsuki, Muneeswar Gupta Nittala, Swetha Bindu Velaga, Dwight Stambolian, Margaret A. Pericak-Vance, Jonathan L. Haines, SriniVas R. Sadda
Summary: This study compared the size of drusen (apical height and basal width) measured on color photos and OCT B-scans in eyes with age-related macular degeneration (AMD) and normal aging. The results show that the apical height and basal width of drusen on OCT images have a certain correspondence with their size on color photos.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Engineering, Biomedical
Boris Babenko, Akinori Mitani, Ilana Traynis, Naho Kitade, Preeti Singh, April Y. Maa, Jorge Cuadros, Greg S. Corrado, Lily Peng, Dale R. Webster, Avinash Varadarajan, Naama Hammel, Yun Liu
Summary: Deep-learning models trained on external eye photographs can accurately detect diabetic retinopathy, diabetic macular oedema, and poor blood glucose control. These models outperform logistic regression models relying on demographic and medical history data. They can be generalized to patients with dilated pupils, patients from different screening programs, and general eye care programs.
NATURE BIOMEDICAL ENGINEERING
(2022)
Article
Ophthalmology
Vishwanath, Deepak T. Swamy, Daneshwari S. Gaddi
Summary: This study examines the feasibility of using smartphones for retinal imaging in resource-limited settings. The results show that clear retinal images can be captured using smartphones, making it a cost-effective and portable alternative method. Therefore, smartphone imaging technology has the potential to revolutionize retinal imaging and enhance healthcare in underserved areas.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Article
Ophthalmology
Deepak Swamy, Daneshwari Gaddi
Summary: This study explores the use of smartphone fundus photography for retinal imaging in resource-limited settings. By using smartphones to capture retinal images, clear images can be obtained to document retinal changes in different clinical conditions. Smartphones, as a low-cost alternative, have revolutionized the way retinal imaging and screening programs are conducted.
INDIAN JOURNAL OF OPHTHALMOLOGY
(2023)
Review
Ecology
Cynthia Tedore
Summary: Quantifying how colors stimulate animal eyes is crucial in various areas of biology. This study compares different measurement methods and finds that filters mimicking photoreceptor spectral sensitivity curves and reflectance spectrometry are the most accurate techniques. Statistical filters trained on a library of natural spectra can be reasonably accurate, but filters trained on a color chart are highly unreliable.
METHODS IN ECOLOGY AND EVOLUTION
(2023)
Article
Ophthalmology
Tae Keun Yoo, Bo Yi Kim, Hyun Kyo Jeong, Hong Kyu Kim, Donghyun Yang, Ik Hee Ryu
Summary: In this study, a deep learning approach was used to segment and evaluate central serous chorioretinopathy (CSC) using fundus photographs. The results showed that the proposed U-Net model based on pix2pix algorithm had good segmentation performance and could accurately detect SRF lesions. This method can be easily implemented in a web-based environment without prior coding skills or personal computing resources.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Article
Ophthalmology
Deniz Oncel, Giulia Corradetti, Ye He, Maryam Ashrafkhorasani, Muneeswar Gupta Nittala, Dwight Stambolian, Margaret A. Pericak-Vance, Jonathan L. Haines, Srinivas R. Sadda
Summary: This study aimed to investigate the correspondence between intraretinal hyperreflective foci (IHRF) identified on OCT B-scans with hyperpigmentation on CFP or hyperreflectivity on IR images. The results showed that less than two-thirds of IHRF manifest as hyperpigmentation on colour photos, and IHRF with posterior shadowing are more likely to be evident as pigment.
ACTA OPHTHALMOLOGICA
(2023)
Article
Engineering, Biomedical
Mark Draelos, Pablo Ortiz, Ruobing Qian, Christian Viehland, Ryan McNabb, Kris Hauser, Anthony N. Kuo, Joseph A. Izatt
Summary: A robot-mounted scanner enables autonomous contactless imaging of the eyes at safe distances, without the need for operator intervention or head stabilization. The robotic OCT scanner can capture high-quality OCT volumetric datasets and may facilitate the diagnosis and monitoring of eye conditions in non-specialist clinics.
NATURE BIOMEDICAL ENGINEERING
(2021)
Article
Ophthalmology
Jochen Straub, Robert A. Sprowl
Summary: This study aims to help readers understand the technical and optical aspects of fundus photography and evaluate the different options available for traditional fundus cameras and smartphone-based adapters. It discusses the technical and optical principles of fundus photography, including illumination, imaging, image capture and alignment. It also highlights the importance of field of view, pupil size, mydriasis and image quality in fundus photography.
Article
Biochemistry & Molecular Biology
Hetian Lei, Cynthia X. Qian, Jinghu Lei, Luis J. Haddock, Shizuo Mukai, Andrius Kazlauskas
MOLECULAR AND CELLULAR BIOLOGY
(2015)
Editorial Material
Ophthalmology
Yoshihiro Yonekawa, Luis J. Haddock, Dean Eliott
JAMA OPHTHALMOLOGY
(2015)
Article
Ophthalmology
Ellen H. Koo, Luis J. Haddock, Namita Bhardwaj, Jorge A. Fortun
BRITISH JOURNAL OF OPHTHALMOLOGY
(2017)
Review
Ophthalmology
Molly Orban, Yasmin Florence Khodeja Islam, Luis J. Haddock
JOURNAL OF OPHTHALMOLOGY
(2016)
Article
Ophthalmology
Molly W. Orban, Luis J. Haddock
OPHTHALMIC SURGERY LASERS & IMAGING RETINA
(2016)
Article
Ophthalmology
Parth Shah, Jill S. Zaveri, Luis J. Haddock
OPHTHALMIC SURGERY LASERS & IMAGING RETINA
(2018)
Article
Ophthalmology
Hasenin Al-Khersan, Jonathan F. Russell, Thomas A. Lazzarini, Nathan L. Scott, John W. Hinkle, Nimesh A. Patel, Nicolas A. Yannuzzi, Benjamin J. Fowler, Rehan M. Hussain, Anita Barikian, Jayanth Sridhar, Stephen R. Russell, Luis J. Haddock, William E. Smiddy, Seenu M. Hariprasad, Yingying Shi, Liang Wang, William Feuer, Giovanni Gregori, Philip J. Rosenfeld
Summary: Ophthalmologists across different training levels showed equal accuracy in identifying diabetic neovascularization using swept-source optical coherence tomography angiography (SS-OCTA) and fluorescein angiography (FA). This suggests that SS-OCTA may be a suitable standalone modality for diagnosing diabetic neovascularization.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Karen R. Brown, Nicolas A. Yannuzzi, William E. Smiddy, Ninel Z. Gregori, Audina M. Berrocal, Luis J. Haddock, Stephen G. Schwartz, Wen-Hsiang Lee, Jayanth Sridhar, David M. Wu, Harry W. Flynn, Justin H. Townsend
Summary: This study aimed to describe the clinical features and outcomes in patients with rhegmatogenous retinal detachment (RRD) after intravitreal injection of pharmacologic agents. The results showed that although RRD after intravitreal injection is rare, prior retinal surgery and alternate risk factors may predispose to RRD after intravitreal injection. Surgical outcomes were generally favorable, but visual acuity outcomes were limited by macula-off RRD and underlying macular disease.
OPHTHALMOLOGY RETINA
(2021)
Article
Ophthalmology
Jose J. Echegaray, Elizabeth A. Vanner, Lily Zhang, Jorge A. Fortun, Thomas A. Albini, Audina M. Berrocal, William E. Smiddy, Harry W. Flynn, Jayanth Sridhar, Ninel Z. Gregori, Justin H. Townsend, Janet L. Davis, Luis J. Haddock
Summary: This study compared the effectiveness of different surgical approaches for repairing primary uncomplicated rhegmatogenous retinal detachment and found that scleral buckling plus PPV resulted in better single-operation anatomic success compared to PPV alone. Retinal redetachments often occurred within the early postoperative period, and achieving single-operation anatomic success was associated with significant improvement in visual acuity.
OPHTHALMOLOGY RETINA
(2021)
Article
Ophthalmology
Nimesh A. Patel, Kenneth C. Fan, Nicolas A. Yannuzzi, Jorge A. Fortun, Luis J. Haddock, Sonia H. Yoo, Patrice J. Persad, Elizabeth A. Vanner, Sarah P. Read, Basil K. Williams, Jayanth Sridhar, Thomas A. Albini, Harry W. Flynn, Kendall Donaldson, Justin H. Townsend
CLINICAL OPHTHALMOLOGY
(2020)
Article
Ophthalmology
Nimesh A. Patel, Parth Shah, Nicolas A. Yannuzzi, Zubair Ansari, Jill S. Zaveri, Nidhi Relhan, Basil K. Williams, Ajay E. Kuriyan, Christopher R. Henry, Jayanth Sridhar, Luis Haddock, Jorge A. Fortun, Thomas A. Albini, Janet L. Davis, Harry W. Flynn
CLINICAL OPHTHALMOLOGY
(2018)
Article
Ophthalmology
Allister Gibbons, Ella H. Leung, Luis J. Haddock, Carlos A. Medina, Viviana Fernandez, Jean-Marie A. Parel, Heather A. Durkee, Guillermo Amescua, Eduardo C. Alfonso, Victor L. Perez
CLINICAL OPHTHALMOLOGY
(2018)
Article
Humanities, Multidisciplinary
Rajni Singh, Seema K. Ladsaria
TRAMES-JOURNAL OF THE HUMANITIES AND SOCIAL SCIENCES
(2017)
Article
Humanities, Multidisciplinary
Yan Zi-Ling
SUN YAT-SEN JOURNAL OF HUMANITIES
(2016)
Article
Computer Science, Information Systems
W. G. C. W. Kumara, Timothy K. Shih, Shih-Ming Chang
JOURNAL OF INFORMATION SCIENCE AND ENGINEERING
(2015)