Journal
JOURNAL OF INTEGRATIVE AGRICULTURE
Volume 17, Issue 8, Pages 1822-1832Publisher
ELSEVIER SCI LTD
DOI: 10.1016/S2095-3119(17)61839-2
Keywords
nanospheres; pyraclostrobin; PLGA; physical and chemical properties; slow release
Categories
Funding
- National Key R&D Program of China [2017YFD0200301, 2016YFD0200500]
Ask authors/readers for more resources
We used poly (lactic-co-glycolic acid) (PLGA) as a carrier polymer for pyraclostrobin-loaded nanospheres. Using the ultrasound emulsification-solvent evaporation method, the physicochemical characteristics and release properties of the pyraclostrobin-loaded nanospheres were studied by dialysis. The optimal nanospheres prepared had a diameter of 0.6 mu m, an active ingredient loading of 17.2%, and a loading rate of 89.7%. Infrared spectroscopy data and differential scanning calorimetry revealed that pyraclostrobin was successfully embedded in the carrier PLGA, and photostability tests indicated enhanced ultraviolet resistance of pyraclostrobin-loaded PLGA nanospheres nanospheres. Release property testing indicated that smaller particles had a faster release rate. Nanospheres also had a faster release rate in slightly acidic and slightly basic environments than in a neutral condition. Agitated nanospheres had a faster release rate than immobile nanospheres. The cumulative release kinetics of pyraclostrobin-loaded nanospheres was consistent with the first order kinetic equation and the Weibull equation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available