Insulin therapy improves islet functions by restoring pancreatic vasculature in high-fat diet-fed streptozotocin-diabetic rats (胰岛素治疗通过恢复胰腺血管提高高脂饮食联合链脲佐菌素诱导的糖尿病大鼠的胰岛功能)

Infusion of Mesenchymal Stem Cells Ameliorates Hyperglycemia in Type 2 Diabetic Rats: Identification of a Novel Role in Improving Insulin Sensitivity

(2012) Y. Si et al.   DIABETES

Effects of Exercise on AMPK Signaling and Downstream Components to PI3K in Rat with Type 2 Diabetes

(2012) Shicheng Cao et al.   PLoS One

High glucose-induced apoptosis in human coronary artery endothelial cells involves up-regulation of death receptors

(2011) Shun-ichiro Kageyama et al.   Cardiovascular Diabetology

Glucose and Inflammation Control Islet Vascular Density and β-Cell Function in NOD Mice

(2011) Eitan M. Akirav et al.   DIABETES

Progression of Carotid Artery Intima-Media Thickness During 12 Years in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study

(2011) J. F. Polak et al.   DIABETES

Short-Term Intensive Therapy in Newly Diagnosed Type 2 Diabetes Partially Restores Both Insulin Sensitivity and β-Cell Function in Subjects With Long-Term Remission

(2011) Yun Hu et al.   DIABETES CARE

Berberine Improves Glucose Metabolism in Diabetic Rats by Inhibition of Hepatic Gluconeogenesis

(2011) Xuan Xia et al.   PLoS One

PI3K and ERK-Induced Rac1 Activation Mediates Hypoxia-Induced HIF-1α Expression in MCF-7 Breast Cancer Cells

(2011) Jun Du et al.   PLoS One

DCCT and EDIC Studies in Type 1 Diabetes: Lessons for Diabetic Neuropathy Regarding Metabolic Memory and Natural History

(2010) Rodica Pop-Busui et al.   Current Diabetes Reports

Changes in islet microvasculature following streptozotocin-induced β-cell loss and subsequent replacement in the neonatal rat

(2010) J Michael Nicholson et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Conversion of adult pancreatic α-cells to β-cells after extreme β-cell loss

(2010) Fabrizio Thorel et al.   NATURE

Beta-cell selective KATP-channel activation protects beta-cells and human islets from human islet amyloid polypeptide induced toxicity

(2010) Robert A. Ritzel et al.   REGULATORY PEPTIDES

Increased carnitine palmitoyl transferase 1 expression and decreased sterol regulatory element–binding protein 1c expression are associated with reduced intramuscular triglyceride accumulation after insulin therapy in high-fat–diet and streptozotocin-induced diabetic rats

(2009) Yan Bi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Insulin Signaling in the Pancreatic β-Cell

(2008) Ingo B. Leibiger et al.   Annual Review of Nutrition

Hyperglycemia-Induced Reactive Oxygen Species Toxicity to Endothelial Cells Is Dependent on Paracrine Mediators

(2008) J. V. Busik et al.   DIABETES

Acute Modulation of Toll-Like Receptors by Insulin

(2008) H. Ghanim et al.   DIABETES CARE

Beneficial Effects of Insulin on Glycemic Control and  -Cell Function in Newly Diagnosed Type 2 Diabetes With Severe Hyperglycemia After Short-Term Intensive Insulin Therapy

(2008) H.-S. Chen et al.   DIABETES CARE

Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction

(2008) Vincent Poitout et al.   ENDOCRINE REVIEWS

Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial

(2008) Jianping Weng et al.   LANCET

Effects of beta-cell rest on beta-cell function: a review of clinical and preclinical data

(2008) Rebecca J Brown et al.   PEDIATRIC DIABETES