Broad protective immune responses elicited by bacterium-like particle-based intranasal pneumococcal particle vaccine displaying PspA2 and PspA4 fragments

Elucidating the impact of the pneumococcal conjugate vaccine programme on pneumonia, sepsis and otitis media hospital admissions in England using a composite control

(2018) Dominic Thorrington et al.   BMC Medicine

Rabies post-exposure prophylaxis for a male with severe Henoch Schönlein purpura following rabies vaccination

(2018) Zheng-Gang Zhu et al.   Human Vaccines & Immunotherapeutics

Current status and future directions of invasive pneumococcal diseases and prophylactic approaches to control them

(2018) Paeton L. Wantuch et al.   Human Vaccines & Immunotherapeutics

Systemic and mucosal immune responses elicited by intranasal immunization with a pneumococcal bacterium-like particle-based vaccine displaying pneumolysin mutant Plym2

(2017) Jingcai Lu et al.   IMMUNOLOGY LETTERS

The distribution and annual changes in the Streptococcus pneumoniae serotypes in adult Japanese patients with pneumococcal pneumonia from 2011 to 2015

(2017) Kentaro Akata et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Mucosal vaccines: a paradigm shift in the development of mucosal adjuvants and delivery vehicles

(2015) Atul Srivastava et al.   APMIS

Protective Immune Responses Elicited by Fusion Protein Containing PsaA and PspA Fragments

(2015) Jingcai Lu et al.   IMMUNOLOGICAL INVESTIGATIONS

Detoxified pneumolysin derivative plym2 directly protects against pneumococcal infection via induction of inflammatory cytokines

(2014) Jingcai Lu et al.   IMMUNOLOGICAL INVESTIGATIONS

Protective properties of a fusion pneumococcal surface protein A (PspA) vaccine against pneumococcal challenge by five different PspA clades in mice

(2014) Zhenyu Piao et al.   VACCINE

Inactivated influenza vaccine adjuvanted with Bacterium-like particles induce systemic and mucosal influenza A virus specific T-cell and B-cell responses after nasal administration in a TLR2 dependent fashion

(2014) C. Keijzer et al.   VACCINE

Current status and perspectives on protein-based pneumococcal vaccines

(2013) Michelle Darrieux et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Streptococcus pneumoniaeinfection: a Canadian perspective

(2013) Xianding Deng et al.   Expert Review of Anti-Infective Therapy

Global burden of childhood pneumonia and diarrhoea

(2013) Christa L Fischer Walker et al.   LANCET

Bacterium-Like Particles for Efficient Immune Stimulation of Existing Vaccines and New Subunit Vaccines in Mucosal Applications

(2013) Natalija Van Braeckel-Budimir et al.   Frontiers in Immunology

PspA Family Distribution, unlike Capsular Serotype, Remains Unaltered following Introduction of the Heptavalent Pneumococcal Conjugate Vaccine

(2012) Christina M. Croney et al.   Clinical and Vaccine Immunology

Bacterium-like particles supplemented with inactivated influenza antigen induce cross-protective influenza-specific antibody responses through intranasal administration

(2012) Aalzen de Haan et al.   VACCINE

Next generation pneumococcal vaccines

(2011) Kristin L Moffitt et al.   CURRENT OPINION IN IMMUNOLOGY

Diversity of pneumococcal surface protein A (PspA) and relation to sequence typing in Streptococcus pneumoniae causing invasive disease in Chinese children

(2011) J. Qian et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Intranasal immunization with recombinant PspA fused with a flagellin enhances cross-protective immunity against Streptococcus pneumoniae infection in mice

(2011) Chung Truong Nguyen et al.   VACCINE

A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae

(2011) Philippe Denoël et al.   VACCINE

Selection of family 1 PspA molecules capable of inducing broad-ranging cross-reactivity by complement deposition and opsonophagocytosis by murine peritoneal cells

(2011) Cibelly Goulart et al.   VACCINE

Intranasal Delivery of Influenza Subunit Vaccine Formulated with GEM Particles as an Adjuvant

(2010) Vinay Saluja et al.   AAPS Journal

Immunization of Mice with Single PspA Fragments Induces Antibodies Capable of Mediating Complement Deposition on Different Pneumococcal Strains and Cross-Protection

(2010) A. T. Moreno et al.   Clinical and Vaccine Immunology

Protection against nasal colonization with Streptococcus pneumoniae by parenteral immunization with a DNA vaccine encoding PspA (Pneumococcal surface protein A)

(2010) Daniela M. Ferreira et al.   MICROBIAL PATHOGENESIS

PspA Family Fusion Proteins Delivered by Attenuated Salmonella enterica Serovar Typhimurium Extend and Enhance Protection against Streptococcus pneumoniae

(2009) W. Xin et al.   INFECTION AND IMMUNITY

Neonatal mucosal immunization with a non-living, non-genetically modified Lactococcus lactis vaccine carrier induces systemic and local Th1-type immunity and protects against lethal bacterial infection

(2009) K Ramirez et al.   Mucosal Immunology

Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction

(2008) Helen Marriott et al.   CURRENT MOLECULAR MEDICINE

Recognition of pneumococcal isolates by antisera raised against PspA fragments from different clades

(2008) M. Darrieux et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Serotype Replacement and Multiple Resistance in Streptococcus pneumoniae After the Introduction of the Conjugate Pneumococcal Vaccine

(2008) Robertino Mera et al.   Microbial Drug Resistance