Vaccines against invasive Salmonella disease

Re-examination of immune response and estimation of anti-Vi IgG protective threshold against typhoid fever-based on the efficacy trial of Vi conjugate in young children

(2014) Shousun C. Szu et al.   VACCINE

Purification of O-specific polysaccharide from lipopolysaccharide produced by Salmonella enterica serovar Paratyphi A

(2014) Sudeep Kothari et al.   VACCINE

A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on Generalized Modules for Membrane Antigens (GMMA)

(2014) Oliver Koeberling et al.   VACCINE

Immune response variations to Salmonella enterica serovar Typhi recombinant porin proteins in mice

(2013) Hoda Toobak et al.   BIOLOGICALS

Comparing the Roles of Antibodies to Nontyphoidal Salmonella enterica in High- and Low-Income Countries and Implications for Vaccine Development

(2013) Calman A. MacLennan et al.   Clinical and Vaccine Immunology

Immunoproteomic Analysis of Antibody in Lymphocyte Supernatant in Patients with Typhoid Fever in Bangladesh

(2013) Richelle C. Charles et al.   Clinical and Vaccine Immunology

Role of Antilipopolysaccharide Antibodies in Serum Bactericidal Activity against Salmonella enterica Serovar Typhimurium in Healthy Adults and Children in the United States

(2013) Estela Trebicka et al.   Clinical and Vaccine Immunology

Differential timing of antibody-mediated phagocytosis and cell-free killing of invasive AfricanSalmonellaallows immune evasion

(2013) Matthew K. Siggins et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Invasive nontyphoidalSalmonelladisease in Africa: current status

(2013) Calman A MacLennan et al.   Expert Review of Anti-Infective Therapy

Increasing rates ofSalmonellaParatyphi A and the current status of its vaccine development

(2013) Sushant Sahastrabuddhe et al.   Expert Review of Vaccines

Development of Vi conjugate – a new generation of typhoid vaccine

(2013) Shousun Chen Szu   Expert Review of Vaccines

Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

(2013) Karen L Kotloff et al.   LANCET

Immunogenicity and safety of the Vi-CRM197 conjugate vaccine against typhoid fever in adults, children, and infants in south and southeast Asia: results from two randomised, observer-blind, age de-escalation, phase 2 trials

(2013) Zulfiqar A Bhutta et al.   LANCET INFECTIOUS DISEASES

Inherited IL-12p40 Deficiency

(2013) Carolina Prando et al.   MEDICINE

Invasive African Salmonella Typhimurium induces bactericidal antibodies against O-antigens

(2013) Simona Rondini et al.   MICROBIAL PATHOGENESIS

Sustained Protection in Mice Immunized with Fractional Doses of Salmonella Enteritidis Core and O Polysaccharide-Flagellin Glycoconjugates

(2013) Raphael Simon et al.   PLoS One

Head-to-Head Comparison of Humoral Immune Responses to Vi Capsular Polysaccharide and Salmonella Typhi Ty21a Typhoid Vaccines–A Randomized Trial

(2013) Anu Kantele et al.   PLoS One

Enhancement of Host Immune Responses by Oral Vaccination to Salmonella enterica serovar Typhimurium Harboring Both FliC and FljB Flagella

(2013) Jeong Seon Eom et al.   PLoS One

Vaccines for low-income countries

(2013) Calman A. MacLennan   SEMINARS IN IMMUNOLOGY

Developing Countries Vaccine Manufacturers Network: Doing good by making high-quality vaccines affordable for all

(2013) Sonia Pagliusi et al.   VACCINE

Immune profiling with a Salmonella Typhi antigen microarray identifies new diagnostic biomarkers of human typhoid

(2013) Li Liang et al.   Scientific Reports

A scalable method for O-antigen purification applied to various Salmonella serovars

(2012) F. Micoli et al.   ANALYTICAL BIOCHEMISTRY

Live Oral Typhoid Vaccine Ty21a Induces Cross-Reactive Humoral Immune Responses against Salmonella enterica Serovar Paratyphi A andS. Paratyphi B in Humans

(2012) Rezwanul Wahid et al.   Clinical and Vaccine Immunology

Systemic Flagellin Immunization Stimulates Mucosal CD103+ Dendritic Cells and Drives Foxp3+ Regulatory T Cell and IgA Responses in the Mesenteric Lymph Node

(2012) A. Flores-Langarica et al.   JOURNAL OF IMMUNOLOGY

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa

(2012) Nicholas A Feasey et al.   LANCET

Community-acquired bacterial bloodstream infections in developing countries in south and southeast Asia: a systematic review

(2012) Jacqueline Deen et al.   LANCET INFECTIOUS DISEASES

Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa

(2012) Chinyere K Okoro et al.   NATURE GENETICS

Differing Burden and Epidemiology of Non-Typhi Salmonella Bacteremia in Rural and Urban Kenya, 2006–2009

(2012) Collins Tabu et al.   PLoS One

Population-Based Incidence of Typhoid Fever in an Urban Informal Settlement and a Rural Area in Kenya: Implications for Typhoid Vaccine Use in Africa

(2012) Robert F. Breiman et al.   PLoS One

High Yield Production Process for Shigella Outer Membrane Particles

(2012) Francesco Berlanda Scorza et al.   PLoS One

Evaluation of Salmonella enterica Serovar Typhimurium TTSS-2 Deficient fur Mutant as Safe Live-Attenuated Vaccine Candidate for Immunocompromised Mice

(2012) Vikalp Vishwakarma et al.   PLoS One

O:2-CRM197 Conjugates against Salmonella Paratyphi A

(2012) Francesca Micoli et al.   PLoS One

Identification of a common immune signature in murine and human systemic Salmonellosis

(2012) S.-J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live oral typhoid vaccine Salmonella Typhi Ty21a – A surrogate vaccine against non-typhoid salmonella?

(2012) Anu Kantele et al.   VACCINE

A bivalent vaccine to protect against Streptococcus pneumoniae and Salmonella typhi

(2012) Ying-Jie Lu et al.   VACCINE

Cross-reactive gut-directed immune response against Salmonella enterica serovar Paratyphi A and B in typhoid fever and after oral Ty21a typhoid vaccination

(2012) Sari H. Pakkanen et al.   VACCINE

Effectiveness of Vi capsular polysaccharide typhoid vaccine among children: A cluster randomized trial in Karachi, Pakistan

(2012) M. Imran Khan et al.   VACCINE

Preparation and evaluation of immunogenic conjugates ofSalmonella entericaserovar Typhi O-specific polysaccharides with diphtheria toxoid

(2012) Aamir Ali et al.   Human Vaccines & Immunotherapeutics

Glycoconjugate vaccine strategies for protection against invasiveSalmonellainfections

(2012) Raphael Simon et al.   Human Vaccines & Immunotherapeutics

Immunity to Intracellular Salmonella Depends on Surface-associated Antigens

(2012) Somedutta Barat et al.   PLoS Pathogens

Evaluation of the Immunogenicity and Biological Activity of theCitrobacter freundiiVi-CRM197Conjugate as a Vaccine forSalmonella entericaSerovar Typhi

(2011) Simona Rondini et al.   Clinical and Vaccine Immunology

The Vi Conjugate Typhoid Vaccine Is Safe, Elicits Protective Levels of IgG Anti-Vi, and Is Compatible with Routine Infant Vaccines

(2011) Vu Dinh Thiem et al.   Clinical and Vaccine Immunology

Invasive Bacterial and Fungal Infections Among Hospitalized HIV-Infected and HIV-Uninfected Adults and Adolescents in Northern Tanzania

(2011) J. A. Crump et al.   CLINICAL INFECTIOUS DISEASES

Soluble flagellin, FliC, induces an Ag-specific Th2 response, yet promotes T-bet-regulated Th1 clearance of Salmonella typhimurium infection

(2011) Saeeda Bobat et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Salmonellaexpressing detoxified lipopolysaccharide is immunogenic and protective both as an attenuated vaccine and for delivery of foreign antigens

(2011) James E Galen et al.   Expert Review of Vaccines

Hyporesponsiveness and its clinical implications after vaccination with polysaccharide or glycoconjugate vaccines

(2011) Jan Poolman et al.   Expert Review of Vaccines

Engineering and Preclinical Evaluation of Attenuated Nontyphoidal Salmonella Strains Serving as Live Oral Vaccines and as Reagent Strains

(2011) Sharon M. Tennant et al.   INFECTION AND IMMUNITY

Salmonella enterica Serovar Enteritidis Core O Polysaccharide Conjugated to H:g,m Flagellin as a Candidate Vaccine for Protection against Invasive Infection withS.Enteritidis

(2011) Raphael Simon et al.   INFECTION AND IMMUNITY

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Salmonella enterica Serovar Typhimurium Lacking hfq Gene Confers Protective Immunity against Murine Typhoid

(2011) Uday Shankar Allam et al.   PLoS One

Safety, Immunogenicity and Dose Ranging of a New Vi-CRM197 Conjugate Vaccine against Typhoid Fever: Randomized Clinical Testing in Healthy Adults

(2011) Pierre van Damme et al.   PLoS One

Physico-chemical properties of Salmonella typhi Vi polysaccharide–diphtheria toxoid conjugate vaccines affect immunogenicity

(2011) So Jung An et al.   VACCINE

An attenuated Salmonella enterica serovar Typhimurium strain lacking the ZnuABC transporter induces protection in a mouse intestinal model of Salmonella infection

(2011) M. Pesciaroli et al.   VACCINE

Room temperature stabilization of oral, live attenuated Salmonella enterica serovar Typhi-vectored vaccines

(2011) Satoshi Ohtake et al.   VACCINE

Immune suppression induced by Vi capsular polysaccharide is overcome by Vi-DT conjugate vaccine

(2011) So Jung An et al.   VACCINE

Production of a conjugate vaccine for Salmonella enterica serovar Typhi from Citrobacter Vi

(2011) F. Micoli et al.   VACCINE

Cell-Associated Flagella Enhance the Protection Conferred by Mucosally-Administered Attenuated Salmonella Paratyphi A Vaccines

(2011) Orit Gat et al.   PLoS Neglected Tropical Diseases

A Salmonella Typhimurium-Typhi Genomic Chimera: A Model to Study Vi Polysaccharide Capsule Function In Vivo

(2011) Angela M. Jansen et al.   PLoS Pathogens

Oral priming with Salmonella Typhi vaccine strain CVD 909 followed by parenteral boost with the S. Typhi Vi capsular polysaccharide vaccine induces CD27+IgD− S. Typhi-specific IgA and IgG B memory cells in humans

(2010) Rezwanul Wahid et al.   CLINICAL IMMUNOLOGY

Population impact of Vi capsular polysaccharide vaccine

(2010) M Imran Khan et al.   Expert Review of Vaccines

Reverse Vaccinology: Developing Vaccines in the Era of Genomics

(2010) Alessandro Sette et al.   IMMUNITY

Typhoid in Kenya Is Associated with a Dominant Multidrug-Resistant Salmonella enterica Serovar Typhi Haplotype That Is Also Widespread in Southeast Asia

(2010) S. Kariuki et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Community-acquired bloodstream infections in Africa: a systematic review and meta-analysis

(2010) Elizabeth A Reddy et al.   LANCET INFECTIOUS DISEASES

A Randomised Trial Evaluating the Safety and Immunogenicity of the Novel Single Oral Dose Typhoid Vaccine M01ZH09 in Healthy Vietnamese Children

(2010) Tran Tinh Hien et al.   PLoS One

Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in Africans

(2010) E. N. Gondwe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulated Humoral Immunity to Nontyphoidal Salmonella in HIV-Infected African Adults

(2010) C. A. MacLennan et al.   SCIENCE

Salmonella enterica serovar Typhimurium ruvB mutant can confer protection against salmonellosis in mice

(2010) Jeongjoon Choi et al.   VACCINE

In a randomized, double-blinded, placebo-controlled trial, the single oral dose typhoid vaccine, M01ZH09, is safe and immunogenic at doses up to 1.7×1010 colony-forming units

(2010) C.E. Lyon et al.   VACCINE

Vi-CRM197 as a new conjugate vaccine against Salmonella Typhi

(2010) F. Micoli et al.   VACCINE

Identification by PCR of Non-typhoidal Salmonella enterica Serovars Associated with Invasive Infections among Febrile Patients in Mali

(2010) Sharon M. Tennant et al.   PLoS Neglected Tropical Diseases

Physical and Chemical Characterization and Immunologic Properties of Salmonella enterica Serovar Typhi Capsular Polysaccharide-Diphtheria Toxoid Conjugates

(2009) C. Cui et al.   Clinical and Vaccine Immunology

Kinetics of the Natural, Humoral Immune Response to Salmonella enterica Serovar Typhi in Kathmandu, Nepal

(2009) A. S. Pulickal et al.   Clinical and Vaccine Immunology

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

(2009) R. A. Kingsley et al.   GENOME RESEARCH

Non-typhoidal salmonellae: a management challenge for children with community-acquired invasive disease in tropical African countries

(2009) Stephen M Graham et al.   LANCET

A Cluster-Randomized Effectiveness Trial of Vi Typhoid Vaccine in India

(2009) Dipika Sur et al.   NEW ENGLAND JOURNAL OF MEDICINE

The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response

(2009) C. Gil-Cruz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidemics of InvasiveSalmonella entericaSerovar Enteritidis andS. entericaSerovar Typhimurium Infection Associated with Multidrug Resistance among Adults and Children in Malawi

(2008) Melita A. Gordon et al.   CLINICAL INFECTIOUS DISEASES

Novel primary immunodeficiencies revealed by the investigation of paediatric infectious diseases

(2008) Jacinta Bustamante et al.   CURRENT OPINION IN IMMUNOLOGY

Salmonella enterica Serovar Typhimurium Strains with Regulated Delayed Attenuation In Vivo

(2008) R. Curtiss et al.   INFECTION AND IMMUNITY

The neglected role of antibody in protection against bacteremia caused by nontyphoidal strains of Salmonella in African children

(2008) Calman A. MacLennan et al.   JOURNAL OF CLINICAL INVESTIGATION

Generation of specific effector and memory T cells with gut- and secondary lymphoid tissue- homing potential by oral attenuated CVD 909 typhoid vaccine in humans

(2008) R Wahid et al.   Mucosal Immunology

High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi

(2008) Kathryn E Holt et al.   NATURE GENETICS

Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

(2008) Manuela Raffatellu et al.   NATURE MEDICINE

A dynamic view of the spread and intracellular distribution of Salmonella enterica

(2008) Pietro Mastroeni et al.   NATURE REVIEWS MICROBIOLOGY

Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment

(2008) W. Kong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of new generation Salmonella enterica serovar Typhimurium vaccines with regulated delayed attenuation to induce immune responses against PspA

(2008) Y. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA