Tailored immunity by skin antigen-presenting cells

Development and Function of Dendritic Cell Subsets

(2014) Alexander Mildner et al.   IMMUNITY

Migration of dendritic cells: physical principles, molecular mechanisms, and functional implications

(2014) Mélina L. Heuzé et al.   IMMUNOLOGICAL REVIEWS

Particle-based transcutaneous administration of HIV-1 p24 protein to human skin explants and targeting of epidermal antigen presenting cells

(2014) Fiorenza Rancan et al.   JOURNAL OF CONTROLLED RELEASE

Transcutaneous Anti-Influenza Vaccination Promotes Both CD4 and CD8 T Cell Immune Responses in Humans

(2014) A. Vogt et al.   JOURNAL OF IMMUNOLOGY

Differential Capability of Human Cutaneous Dendritic Cell Subsets to Initiate Th17 Responses

(2014) A. R. Mathers et al.   JOURNAL OF IMMUNOLOGY

Priming of CD8+ and CD4+ T Cells in Experimental Leishmaniasis Is Initiated by Different Dendritic Cell Subtypes

(2014) N. Brewig et al.   JOURNAL OF IMMUNOLOGY

Second-Generation Langerhans Cells Originating from Epidermal Precursors Are Essential for CD8+ T Cell Priming

(2014) M. Elnekave et al.   JOURNAL OF IMMUNOLOGY

The Closely Related CD103+ Dendritic Cells (DCs) and Lymphoid-Resident CD8+ DCs Differ in Their Inflammatory Functions

(2014) Zhijun Jiao et al.   PLoS One

Human Inflammatory Dendritic Cells Induce Th17 Cell Differentiation

(2013) Elodie Segura et al.   IMMUNITY

Origins and Functional Specialization of Macrophages and of Conventional and Monocyte-Derived Dendritic Cells in Mouse Skin

(2013) Samira Tamoutounour et al.   IMMUNITY

DEC-205-mediated antigen targeting to steady-state dendritic cells induces deletion of diabetogenic CD8+ T cells independently of PD-1 and PD-L1

(2013) Gayatri Mukherjee et al.   INTERNATIONAL IMMUNOLOGY

Encapsulation of Nod1 and Nod2 receptor ligands into poly(lactic acid) nanoparticles potentiates their immune properties

(2013) Vincent Pavot et al.   JOURNAL OF CONTROLLED RELEASE

Cutting Edge: Identification of the Thymic Stromal Lymphopoietin-Responsive Dendritic Cell Subset Critical for Initiation of Type 2 Contact Hypersensitivity

(2013) M. Kitajima et al.   JOURNAL OF IMMUNOLOGY

Flt3L Dependence Helps Define an Uncharacterized Subset of Murine Cutaneous Dendritic Cells

(2013) Shamim A. Mollah et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells

(2013) William R Heath et al.   NATURE IMMUNOLOGY

Inflammatory dendritic cells in mice and humans

(2013) Elodie Segura et al.   TRENDS IN IMMUNOLOGY

Biodegradable Particles as Vaccine Delivery Systems: Size Matters

(2012) Vijaya B. Joshi et al.   AAPS Journal

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

The differential production of cytokines by human Langerhans cells and dermal CD14+ DCs controls CTL priming

(2012) J. Banchereau et al.   BLOOD

Inflammatory Monocytes Activate Memory CD8+ T and Innate NK Lymphocytes Independent of Cognate Antigen during Microbial Pathogen Invasion

(2012) Saïdi M'Homa Soudja et al.   IMMUNITY

Two Distinct Types of Langerhans Cells Populate the Skin during Steady State and Inflammation

(2012) Kristin Seré et al.   IMMUNITY

Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells

(2012) Julien Seneschal et al.   IMMUNITY

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

(2012) Muzlifah Haniffa et al.   IMMUNITY

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8+ T cells and activating Foxp3+ regulatory T cells

(2012) Mercedes Gomez de Agüero et al.   JOURNAL OF CLINICAL INVESTIGATION

Characterization of resident and migratory dendritic cells in human lymph nodes

(2012) Elodie Segura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Resident CD141 (BDCA3)+dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation

(2012) Chung-Ching Chu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Zbtb46expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages

(2012) Ansuman T. Satpathy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Decoding dendritic cell function through module and network analysis

(2012) Gaurav Pandey et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Deciphering the transcriptional network of the dendritic cell lineage

(2012) Jennifer C Miller et al.   NATURE IMMUNOLOGY

Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin

(2012) Keisuke Nagao et al.   NATURE IMMUNOLOGY

Re(de)fining the dendritic cell lineage

(2012) Ansuman T Satpathy et al.   NATURE IMMUNOLOGY

The influence of PEG chain length and targeting moiety on antibody-mediated delivery of nanoparticle vaccines to human dendritic cells

(2011) Luis J. Cruz et al.   BIOMATERIALS

Langerhans cells regulate cutaneous injury by licensing CD8 effector cells recruited to the skin

(2011) C. L. Bennett et al.   BLOOD

Transcutaneous and intradermal vaccination

(2011) Behazine Combadiere et al.   Human vaccines & immunotherapeutics

Skin-Resident Murine Dendritic Cell Subsets Promote Distinct and Opposing Antigen-Specific T Helper Cell Responses

(2011) Botond Z. Igyártó et al.   IMMUNITY

The Multitasking Organ: Recent Insights into Skin Immune Function

(2011) Paola Di Meglio et al.   IMMUNITY

Dendritic Cell and Macrophage Heterogeneity In Vivo

(2011) Daigo Hashimoto et al.   IMMUNITY

Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome

(2011) Takeshi Ouchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Langerhans cells are negative regulators of the anti-Leishmaniaresponse

(2011) Kordula Kautz-Neu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Expression of XCR1 Defines Mouse Lymphoid-Tissue Resident and Migratory Dendritic Cells of the CD8 + Type

(2011) K. Crozat et al.   JOURNAL OF IMMUNOLOGY

Intradermal Immunization Triggers Epidermal Langerhans Cell Mobilization Required for CD8 T-Cell Immune Responses

(2011) Christelle Liard et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Langerhans cells are precommitted to immune tolerance induction

(2011) E. Shklovskaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Boosting antibody responses by targeting antigens to dendritic cells

(2011) Irina Caminschi et al.   TRENDS IN IMMUNOLOGY

Targeting of HIV-p24 particle-based vaccine into differential skin layers induces distinct arms of the immune responses

(2011) Christelle Liard et al.   VACCINE

Skin-draining lymph nodes contain dermis-derived CD103- dendritic cells that constitutively produce retinoic acid and induce Foxp3+ regulatory T cells

(2010) M. Guilliams et al.   BLOOD

Langerhans cells and more: langerin-expressing dendritic cell subsets in the skin

(2010) Nikolaus Romani et al.   IMMUNOLOGICAL REVIEWS

Differentiation and function of mouse monocyte-derived dendritic cells in steady state and inflammation

(2010) Pilar M. Domínguez et al.   IMMUNOLOGICAL REVIEWS

Distribution and Function of Macrophage Galactose-type C-type Lectin 2 (MGL2/CD301b)

(2010) Kaori Denda-Nagai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Active targeting of dendritic cells with mannan-decorated PLGA nanoparticles

(2010) Zahra Ghotbi et al.   JOURNAL OF DRUG TARGETING

GM-CSF–dependent, CD103+dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization

(2010) Irah L. King et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons

(2010) Josh Gregorio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Acute Ablation of Langerhans Cells Enhances Skin Immune Responses

(2010) A. Bobr et al.   JOURNAL OF IMMUNOLOGY

TGF-  Is Required To Maintain the Pool of Immature Langerhans Cells in the Epidermis

(2010) J. M. Kel et al.   JOURNAL OF IMMUNOLOGY

Human Langerhans Cells Are More Efficient Than CD14−CD1c+ Dermal Dendritic Cells at Priming Naive CD4+ T Cells

(2010) Laetitia Furio et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Differential expression of pathogen-recognition molecules between dendritic cell subsets revealed by plasma membrane proteomic analysis

(2010) Elodie Segura et al.   MOLECULAR IMMUNOLOGY

Dissolving polymer microneedle patches for influenza vaccination

(2010) Sean P Sullivan et al.   NATURE MEDICINE

Preferential Amplification of CD8 Effector-T Cells after Transcutaneous Application of an Inactivated Influenza Vaccine: A Randomized Phase I Trial

(2010) Behazine Combadière et al.   PLoS One

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response

(2009) Stefan Fischer et al.   JOURNAL OF DRUG TARGETING

CD207+CD103+dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

(2009) Sandrine Henri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Langerhans Cells Suppress Contact Hypersensitivity Responses Via Cognate CD4 Interaction and Langerhans Cell-Derived IL-10

(2009) B. Z. Igyarto et al.   JOURNAL OF IMMUNOLOGY

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Murine epidermal Langerhans cells and langerin-expressing dermal dendritic cells are unrelated and exhibit distinct functions

(2009) K. Nagao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production

(2009) H. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

(2008) I. Caminschi et al.   BLOOD

The skin: an indispensable barrier

(2008) Ehrhardt Proksch et al.   EXPERIMENTAL DERMATOLOGY

Functional Specializations of Human Epidermal Langerhans Cells and CD14+ Dermal Dendritic Cells

(2008) Eynav Klechevsky et al.   IMMUNITY

In Vivo Induction of Immune Responses to Pathogens by Conventional Dendritic Cells

(2008) María López-Bravo et al.   IMMUNITY

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION

Psoriasis Is Characterized by Accumulation of Immunostimulatory and Th1/Th17 Cell-Polarizing Myeloid Dendritic Cells

(2008) Lisa C. Zaba et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nanoparticle-Based Targeting of Vaccine Compounds to Skin Antigen-Presenting Cells By Hair Follicles and their Transport in Mice

(2008) Brice Mahe et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Co-delivery of cancer-associated antigen and Toll-like receptor 4 ligand in PLGA nanoparticles induces potent CD8+ T cell-mediated anti-tumor immunity

(2008) Samar Hamdy et al.   VACCINE

Migration of Dendritic Cell Subsets and their Precursors

(2007) Gwendalyn J. Randolph et al.   Annual Review of Immunology