Immunity, immunopathology, and human vaccine development against sexually transmittedChlamydia trachomatis

Signaling via Tumor Necrosis Factor Receptor 1 but Not Toll-Like Receptor 2 Contributes Significantly to Hydrosalpinx Development following Chlamydia muridarum Infection

(2014) Xiaohua Dong et al.   INFECTION AND IMMUNITY

In vivo targeting of human DC-SIGN drastically enhances CD8+T-cell-mediated protective immunity

(2013) Christina Hesse et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Reduced Live Organism Recovery and Lack of Hydrosalpinx in Mice Infected with Plasmid-Free Chlamydia muridarum

(2013) Lei Lei et al.   INFECTION AND IMMUNITY

Human Female Genital Tract Infection by the Obligate Intracellular Bacterium Chlamydia trachomatis Elicits Robust Type 2 Immunity

(2013) Rodolfo D. Vicetti Miguel et al.   PLoS One

Targeting Leishmania major Antigens to Dendritic Cells In Vivo Induces Protective Immunity

(2013) Ines Matos et al.   PLoS One

Development status and future prospects for a vaccine against Chlamydia trachomatis infection

(2013) Louise M. Hafner et al.   VACCINE

Phase I Trial of Overlapping Long Peptides from a Tumor Self-Antigen and Poly-ICLC Shows Rapid Induction of Integrated Immune Response in Ovarian Cancer Patients

(2012) P. Sabbatini et al.   CLINICAL CANCER RESEARCH

CD4+ T Cells Are Necessary and Sufficient To Confer Protection against Chlamydia trachomatis Infection in the Murine Upper Genital Tract

(2012) D. C. Gondek et al.   JOURNAL OF IMMUNOLOGY

A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates

(2011) Laszlo Kari et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Partial protection against chlamydial reproductive tract infection by a recombinant major outer membrane protein/CpG/cholera toxin intranasal vaccine in the guinea pig Chlamydia caviae model

(2011) Dean W. Andrew et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

(2011) J. Idoyaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of a broadly protective Chlamydia–cholera combination vaccine candidate

(2011) F.O. Eko et al.   VACCINE

Targeting of DEC-205 on human dendritic cells results in efficient MHC class II-restricted antigen presentation

(2010) K. Birkholz et al.   BLOOD

C-type lectin DC-SIGN: An adhesion, signalling and antigen-uptake molecule that guides dendritic cells in immunity

(2010) Urban Švajger et al.   CELLULAR SIGNALLING

Vaccination againstChlamydiaGenital Infection Utilizing the MurineC. muridarumModel

(2010) Christina M. Farris et al.   INFECTION AND IMMUNITY

Interleukin-17 Contributes to Generation of Th1 Immunity and Neutrophil Recruitment duringChlamydia muridarumGenital Tract Infection but Is Not Required for Macrophage Influx or Normal Resolution of Infection

(2010) Amy M. Scurlock et al.   INFECTION AND IMMUNITY

Exploiting Antigenic Diversity for Vaccine Design

(2010) Marco Soriani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chlamydia-Specific CD4 T Cell Clones Control Chlamydia muridarum Replication in Epithelial Cells by Nitric Oxide-Dependent and -Independent Mechanisms

(2010) K. Jayarapu et al.   JOURNAL OF IMMUNOLOGY

Duration of Untreated, UncomplicatedChlamydia trachomatisGenital Infection and Factors Associated with Chlamydia Resolution: A Review of Human Studies

(2010) William M. Geisler   JOURNAL OF INFECTIOUS DISEASES

Summary: The Natural History and Immunobiology ofChlamydia trachomatisGenital Infection and Implications for Chlamydia Control

(2010) Sami L. Gottlieb et al.   JOURNAL OF INFECTIOUS DISEASES

Protective Immunity to Chlamydial Genital Infection: Evidence from Animal Studies

(2010) Roger G. Rank et al.   JOURNAL OF INFECTIOUS DISEASES

Pathogenesis of Genital Tract Disease Due toChlamydia trachomatis

(2010) Toni Darville et al.   JOURNAL OF INFECTIOUS DISEASES

Phase I trial of a Toll-like receptor 9 agonist, PF-3512676 (CPG 7909), in patients with treatment-refractory, cutaneous T-cell lymphoma

(2010) Youn H. Kim et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Heat denatured enzymatically inactive recombinant chlamydial protease-like activity factor induces robust protective immunity against genital chlamydial challenge

(2010) Bharat K.R. Chaganty et al.   VACCINE

HIV gag protein is efficiently cross-presented when targeted with an antibody towards the DEC-205 receptor in Flt3 ligand-mobilized murine DC

(2009) Leonia Bozzacco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Determination of chlamydial load and immune parameters in asymptomatic, symptomatic and infertile women

(2009) Tanvi Agrawal et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Identification and characterization of novel recombinant vaccine antigens for immunization against genitalChlamydia trachomatis

(2009) Rhea N. Coler et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

CT043, a Protective Antigen That Induces a CD4+ Th1 Response during Chlamydia trachomatis Infection in Mice and Humans

(2009) E. Meoni et al.   INFECTION AND IMMUNITY

Superior Protective Immunity against Murine Listeriosis by Combined Vaccination with CpG DNA and Recombinant Salmonella enterica Serovar Typhimurium

(2009) C. Berchtold et al.   INFECTION AND IMMUNITY

Role of T Lymphocytes in the Pathogenesis ofChlamydiaDisease

(2009) Joseph U. Igietseme et al.   JOURNAL OF INFECTIOUS DISEASES

ISCOMs and ISCOMATRIX™

(2009) Hong-Xiang Sun et al.   VACCINE

A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice

(2009) Jie Wang et al.   VACCINE

Transcutaneous immunization with a novel lipid-based adjuvant protects against Chlamydia genital and respiratory infections

(2009) Danica K. Hickey et al.   VACCINE

ORIGINAL ARTICLE: A Distinct Cellular Profile Is Seen in the Human Endocervix During Chlamydia trachomatis Infection

(2008) Mercedes Ficarra et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

(2008) I. Caminschi et al.   BLOOD

Targeting DCIR on human plasmacytoid dendritic cells results in antigen presentation and inhibits IFN-  production

(2008) F. Meyer-Wentrup et al.   BLOOD

Protective or pathogenic immune response to genital chlamydial infection in women—A possible role of cytokine secretion profile of cervical mucosal cells

(2008) T. Agrawal et al.   CLINICAL IMMUNOLOGY

Recruitment of myeloid and plasmacytoid dendritic cells in cervical mucosa during Chlamydia trachomatis infection

(2008) T. Agrawal et al.   CLINICAL MICROBIOLOGY AND INFECTION

Dendritic Cells In Vivo: A Key Target for a New Vaccine Science

(2008) Ralph M. Steinman   IMMUNITY

A North American brain tumor consortium phase II study of poly-ICLC for adult patients with recurrent anaplastic gliomas

(2008) Nicholas Butowski et al.   JOURNAL OF NEURO-ONCOLOGY

Access to Care Issues for African American Communities: Implications for STD Disparities

(2008) Deidra D. Parrish et al.   SEXUALLY TRANSMITTED DISEASES

In silico identification and in vivo analysis of a novel T-cell antigen from Chlamydia, NrdB

(2008) Christopher J. Barker et al.   VACCINE