New generation of dendritic cell vaccines

Selection of an Antibody Library Identifies a Pathway to Induce Immunity by Targeting CD36 on Steady-State CD8 + Dendritic Cells

(2014) E. Tagliani et al.   JOURNAL OF IMMUNOLOGY

DNGR-1 is a specific and universal marker of mouse and human Batf3-dependent dendritic cells in lymphoid and nonlymphoid tissues

(2012) L. F. Poulin et al.   BLOOD

Human CD1c (BDCA-1)+ myeloid dendritic cells secrete IL-10 and display an immuno-regulatory phenotype and function in response to Escherichia coli

(2012) Andrew J. Kassianos et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human Tissues Contain CD141hi Cross-Presenting Dendritic Cells with Functional Homology to Mouse CD103+ Nonlymphoid Dendritic Cells

(2012) Muzlifah Haniffa et al.   IMMUNITY

F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells

(2012) Susan Ahrens et al.   IMMUNITY

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

(2012) Jian-Guo Zhang et al.   IMMUNITY

Cutting Edge: Clec9A+ Dendritic Cells Mediate the Development of Experimental Cerebral Malaria

(2012) L. Piva et al.   JOURNAL OF IMMUNOLOGY

Compensatory dendritic cell development mediated by BATF–IRF interactions

(2012) Roxane Tussiwand et al.   NATURE

The secret ally: immunostimulation by anticancer drugs

(2012) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting Dendritic Cells in vivo for Cancer Therapy

(2012) Irina Caminschi et al.   Frontiers in Immunology

The Role of XCR1 and its Ligand XCL1 in Antigen Cross-Presentation by Murine and Human Dendritic Cells

(2012) Richard A. Kroczek et al.   Frontiers in Immunology

Expression of XCR1 Characterizes the Batf3-Dependent Lineage of Dendritic Cells Capable of Antigen Cross-Presentation

(2012) Annabell Bachem et al.   Frontiers in Immunology

CD8α+ Dendritic Cells Are the Critical Source of Interleukin-12 that Controls Acute Infection by Toxoplasma gondii Tachyzoites

(2011) Mona Mashayekhi et al.   IMMUNITY

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets

(2011) Kathrin Kastenmüller et al.   JOURNAL OF CLINICAL INVESTIGATION

Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans

(2011) Marina Caskey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Dendritic Cell Subsets from Spleen and Blood Are Similar in Phenotype and Function but Modified by Donor Health Status

(2011) D. Mittag et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Expression of XCR1 Defines Mouse Lymphoid-Tissue Resident and Migratory Dendritic Cells of the CD8 + Type

(2011) K. Crozat et al.   JOURNAL OF IMMUNOLOGY

Targeting Antigen to Mouse Dendritic Cells via Clec9A Induces Potent CD4 T Cell Responses Biased toward a Follicular Helper Phenotype

(2011) M. H. Lahoud et al.   JOURNAL OF IMMUNOLOGY

Dendritic cell-targeted protein vaccines: a novel approach to induce T-cell immunity

(2011) C. Trumpfheller et al.   JOURNAL OF INTERNAL MEDICINE

Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3−/− mice

(2011) Irina Caminschi et al.   MOLECULAR IMMUNOLOGY

Batf3-Dependent CD11blow/− Peripheral Dendritic Cells Are GM-CSF-Independent and Are Not Required for Th Cell Priming after Subcutaneous Immunization

(2011) Brian T. Edelson et al.   PLoS One

Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates

(2011) B. J. Flynn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A

(2011) J. Idoyaga et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A

(2010) Olivier P. Joffre et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The CD8+dendritic cell subset

(2010) Ken Shortman et al.   IMMUNOLOGICAL REVIEWS

The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+dendritic cells

(2010) Karine Crozat et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human CD141+(BDCA-3)+dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens

(2010) Sarah L. Jongbloed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Superior antigen cross-presentation and XCR1 expression define human CD11c+CD141+cells as homologues of mouse CD8+dendritic cells

(2010) Annabell Bachem et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peripheral CD103+dendritic cells form a unified subset developmentally related to CD8α+conventional dendritic cells

(2010) Brian T. Edelson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mouse CD8α+DCs and human BDCA3+DCs are major producers of IFN-λ in response to poly IC

(2010) Henning Lauterbach et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Characterization of human DNGR-1+BDCA3+leukocytes as putative equivalents of mouse CD8α+dendritic cells

(2010) Lionel Franz Poulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Route of Antigen Uptake Differentially Impacts Presentation by Dendritic Cells and Activated Monocytes

(2010) A. O. Kamphorst et al.   JOURNAL OF IMMUNOLOGY

Targeted Delivery of Tumor Antigens to Activated Dendritic Cells via CD11c Molecules Induces Potent Antitumor Immunity in Mice

(2009) H. Wei et al.   CLINICAL CANCER RESEARCH

Selective Expression of the Chemokine Receptor XCR1 on Cross-presenting Dendritic Cells Determines Cooperation with CD8+ T Cells

(2009) Brigitte G. Dorner et al.   IMMUNITY

The origin and development of nonlymphoid tissue CD103+DCs

(2009) Florent Ginhoux et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD207+CD103+dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

(2009) Sandrine Henri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

What Role Does the Route of Immunization Play in the Generation of Protective Immunity against Mucosal Pathogens?

(2009) I. M. Belyakov et al.   JOURNAL OF IMMUNOLOGY

The C-Type Lectin Clec12A Present on Mouse and Human Dendritic Cells Can Serve as a Target for Antigen Delivery and Enhancement of Antibody Responses

(2009) M. H. Lahoud et al.   JOURNAL OF IMMUNOLOGY

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

Dendritic cell subsets in primary and secondary T cell responses at body surfaces

(2009) William R Heath et al.   NATURE IMMUNOLOGY

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement

(2008) I. Caminschi et al.   BLOOD

Dendritic cell vaccines in melanoma: From promise to proof?

(2008) W.J. Lesterhuis et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms

(2008) Baidong Hou et al.   IMMUNITY

CLEC9A Is a Novel Activation C-type Lectin-like Receptor Expressed on BDCA3+Dendritic Cells and a Subset of Monocytes

(2008) Cristal Huysamen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin

(2008) David Sancho et al.   JOURNAL OF CLINICAL INVESTIGATION

The efficacy of DNA vaccination is enhanced in mice by targeting the encoded protein to dendritic cells

(2008) Godwin Nchinda et al.   JOURNAL OF CLINICAL INVESTIGATION

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

(2008) Sven Burgdorf et al.   NATURE IMMUNOLOGY

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

(2008) K. Hildner et al.   SCIENCE

Intradermal vaccine delivery: Will new delivery systems transform vaccine administration?

(2008) Paul Henri Lambert et al.   VACCINE

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

(2008) Scott H Robbins et al.   GENOME BIOLOGY