Article
Engineering, Biomedical
Guangrui Chai, Deming Zhang, Weijian Hua, Jun Yin, Yifei Jin, Ming Chen
Summary: The study proposed a personalized 3D printing-assisted approach for surgical treatment of pediatric orbital trapdoor fractures, based on numerical simulations and clinical data. Tailor-made absorbable implants and 3D-printed models were used during surgical repairs, resulting in low incidence of diplopia and enophthalmos among patients at 12 months post-op, verifying the efficacy of the novel strategy.
BIOACTIVE MATERIALS
(2021)
Article
Oncology
Max Wilkat, Norbert Kuebler, Majeed Rana
Summary: Curatively intended oncologic surgery in the midface relies on the principle of residual-free tumor excision. Computer assisted surgery (CAS) plays a crucial role in enhancing the accuracy and safety of tumor removal and reconstruction, leading to positive changes in quality of life for patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Medicine, General & Internal
Rasmus Holm Hansen, Jan Duedal Rolfing, Christian Lind Nielsen, Ole Brink, Per Hviid Gundtoft
Summary: The aim of this study was to evaluate if the ADAPT system reduces the number of outliers with a TAD > 20 mm. Unfortunately, the results showed that the use of the ADAPT system did not meet the expectation, as there were still outliers with a TAD > 20 mm. Therefore, the use of the ADAPT system was discontinued.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Shengchi Fan, Gustavo Saenz-Ravello, Leonardo Diaz, Yiqun Wu, Ruben Davo, Feng Wang, Marko Magic, Bilal Al-Nawas, Peer W. Kaemmerer
Summary: The study aimed to evaluate the accuracy of different approaches for zygomatic implant (ZI) placement in patients with severe maxillary problems. The results showed that dynamic computer-aided surgery (d-CAIS) and modified static computer-aided surgery (s-CAIS) had clinically acceptable outcomes, while the conventional s-CAIS had the highest deviation values. Surgeons should be aware of potential deviations and complications regardless of the selected approach.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Long Xia, Chunli Gao, Xi Gong, Yi Zhang, Yang He, Jingang An
Summary: This study compared postoperative enophthalmos between fresh and delayed unilateral orbital fractures after orbital reconstruction with titanium mesh using computer-assisted navigation. The findings showed that postoperative enophthalmos decreased after surgery but increased significantly from 1 week to 6 months postoperatively in both groups. Delta E (difference in the degree of enophthalmos between 1 week and 6 months postoperatively) was similar between patients with fresh and delayed fractures. There was a significant difference in Delta E between patients with single-wall orbital fractures and those with two-wall orbital fractures.
JOURNAL OF CRANIOFACIAL SURGERY
(2023)
Review
Medicine, General & Internal
Sigmar Schnutenhaus, Cornelia Edelmann, Anne Knipper, Ralph G. Luthardt
Summary: This systematic review and meta-analysis aimed to analyze the accuracy of implant placement using computer-assisted dynamic navigation procedures. The results showed that the clinical accuracy of dynamic navigation is comparable to static navigation, but there is great heterogeneity in dynamic navigation systems, indicating a need for further research to validate their feasibility.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Orthopedics
Houyi Sun, Haifeng Zhang, Tianhao Wang, Kai Zheng, Weicheng Zhang, Wenming Li, Wen Zhang, Yaozeng Xu, Dechun Geng
Summary: The drilling location is an important factor in femoral pin-site fracture during navigation-assisted total knee arthroplasty (TKA). Biomechanical analysis and finite-element analysis showed that severely eccentric drilling significantly reduced the biomechanical strength of the femur and increased the risk of pin-site fracture.
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME
(2022)
Article
Dentistry, Oral Surgery & Medicine
Tobias Graf, Christine Keul, Daniel Wismeijer, Jan Frederik Gueth
Summary: The study compared computer-assisted implant planning and surgery (CAIPS) with non-computer-assisted methods, finding that the former had higher time and costs involved. Time was identified as the main driving factor for economic considerations in this context.
CLINICAL ORAL IMPLANTS RESEARCH
(2021)
Review
Health Care Sciences & Services
Ikaasa Suri, Mehr Suri, James Hu, Siddarth Ketan Dedhia, Kurt Yaeger
Summary: This study aims to develop a model that weighs the cost and clinical benefits of a typical 3D navigation platform to determine the number of cases required to justify its purchase. The study found that most US healthcare facilities cannot justify the cost of 3D navigation at current reimbursement levels, highlighting the need for greater pricing flexibility.
JOURNAL OF MEDICAL SYSTEMS
(2023)
Article
Health Care Sciences & Services
Marcel Ebeling, Andreas Sakkas, Alexander Schramm, Frank Wilde, Mario Scheurer, Karsten Winter, Sebastian Pietzka
Summary: The aim of this study was to investigate the precision of implantation on a phantom head according to preliminary planning and the influence of participants' knowledge and experience. Implants were scanned and compared to the 3D-planned placement to measure deviations. The results showed that both implantologists and students had deviations less than 1.78 mm on average from 3D planning, demonstrating the predictability and reproducibility of guided implantology in dental implantology.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Oncology
Iacopo Dallan, Lodovica Cristofani-Mencacci, Giacomo Fiacchini, Mario Turri-Zanoni, Wouter van Furth, Matteo de Notaris, Miriana Picariello, Enrico Alexandre, Christos Georgalas, Luca Bruschini
Summary: Transorbital approaches have shown promising potentials in skull base surgery as versatile surgical routes. They can be a valuable adjunct or even an alternative to traditional routes, providing opportunities for selected patients with intraorbital, skull base, and intra-axial lesions. However, their relatively recent development and unfamiliarity in the skull base community underline the importance of personalized training, adequate case volume, and a dedicated setting for achieving proficiency. Genetic, omics, and biological features should guide the selection of current and future applications in a multidisciplinary environment.
FRONTIERS IN ONCOLOGY
(2022)
Review
Health Care Sciences & Services
Hang-Nga Mai, Van Viet Dam, Du-Hyeong Lee
Summary: This study is the first systematic review and meta-analysis that evaluates the accuracy of dental implant placements using AR navigation. The results indicate that AR navigation is more accurate than the freehand method and conventional navigation, and comparable to template-guided surgery. This review highlights the potential of AR navigation as an effective and accurate surgical guide for dental implant placement.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Multidisciplinary Sciences
D. Zhu, Z. P. Cian, C. Noel, A. Risinger, D. Biswas, L. Egan, Y. Zhu, A. M. Green, C. Huerta Alderete, N. H. Nguyen, Q. Wang, A. Maksymov, Y. Nam, M. Cetina, N. M. Linke, M. Hafezi, C. Monroe
Summary: This paper discusses the importance of cross-platform quantum computing comparisons using randomized and correlated measurements, highlighting the significance of performance validation and comparison of quantum states across different quantum computing platforms.
NATURE COMMUNICATIONS
(2022)
Article
Surgery
Chia-Ying Lin, Chao-Chun Chang, Yi-Sheng Liu, Ying-Yuan Chen, Wu-Wei Lai, Yau-Lin Tseng, Yi-Ting Yen
Summary: This study compared stapled segmentectomy (SS) and non-stapled segmentectomy (NSS) techniques in terms of perioperative outcomes, lung volume preservation, and postoperative lung function, finding that lung volume preservation was not significantly influenced by different segmentectomy techniques. Surgeons should consider individual patient characteristics when choosing a segmentectomy technique.
ASIAN JOURNAL OF SURGERY
(2021)
Article
Medicine, General & Internal
Cornelia Edelmann, Martin Wetzel, Anne Knipper, Ralph G. Luthardt, Sigmar Schnutenhaus
Summary: The study found that precise implantation was possible with the dynamic navigation system used, which can improve the quality of implant positioning, especially in minimally invasive procedures. The clinical trial demonstrated a clinical benefit and effectiveness of dynamic navigation in implant surgery.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Dentistry, Oral Surgery & Medicine
Lara Schorn, Madiha Rana, Anna Madry, Ramin Ipaktchi, Henriette Moellmann, Nils Claudius Gellrich, Majeed Rana
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
(2020)
Article
Otorhinolaryngology
Franziska Sisolefsky, Madiha Rana, Majeed Rana, Philipp Y. Herzberg
Summary: The study demonstrates that a trait-based approach to identifying the level of psychological distress in cancer patients can purposefully and safely assess their stress levels, leading to a new approach in psycho-oncology screening.
Article
Dentistry, Oral Surgery & Medicine
Franziska Sisolefsky, Madiha Rana, Majeed Rana
Summary: The study aimed to identify factors influencing quality of life and psychological stress in oral cancer patients from their perspective. Results showed that patients value their own personality and social support, and desire psycho-oncological assistance. It is important for healthcare providers to understand and address these factors to better support patients.
JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
(2021)
Article
Oncology
Max Wilkat, Norbert Kuebler, Majeed Rana
Summary: Curatively intended oncologic surgery in the midface relies on the principle of residual-free tumor excision. Computer assisted surgery (CAS) plays a crucial role in enhancing the accuracy and safety of tumor removal and reconstruction, leading to positive changes in quality of life for patients.
FRONTIERS IN ONCOLOGY
(2021)
Article
Oncology
Henriette L. Moellmann, Laura Apeltrath, Nadia Karnatz, Max Wilkat, Erik Riedel, Daman Deep Singh, Majeed Rana
Summary: This study compared the accuracy of mandibular reconstruction and clinical outcomes between conventional reconstruction plates (CR) and patient-specific implants (PSI). The results showed no significant differences in reconstruction accuracy and postoperative complications between the two methods, but there were some discrepancies at specific measurement points.
FRONTIERS IN ONCOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Julian Lommen, Lara Schorn, Christoph Sproll, Jan Haussmann, Norbert R. Kubber, Wilfried Budach, Majeed Rana, Balint Tamaskovics
Summary: This study evaluated the CT artifacts and image quality of four polymer plate materials in mandible reconstruction. It found that the polymer plates significantly reduced CT artifacts and improved image quality, facilitating the radiological interpretation of implant surrounding tissues.
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
(2022)
Article
Medicine, General & Internal
Henriette L. Moellmann, Vanessa N. Mehr, Nadia Karnatz, Max Wilkat, Erik Riedel, Majeed Rana
Summary: This study investigates the relationship between the fitting accuracy of patient-specific implants made from polyetheretherketone (PEEK) and the incidence of postoperative complications. It found that while the fitting accuracy was generally high, there was still a considerable complication rate. The focus should be on exploring other risk factors to optimize surgical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Chemistry, Physical
Lara Schorn, Anna Sine, Karin Berr, Jorg Handschel, Rita Depprich, Norbert R. Kuebler, Christoph Sproll, Majeed Rana, Julian Lommen
Summary: The effect of alloplastic and xenogeneic bone grafting materials on the growth rates and viability of human unrestricted somatic stem cells was investigated in vitro. The results showed that xenogeneic materials promoted the greatest proliferation and improved viability of the cells. Furthermore, the pore size and bioactive characteristics of the scaffolds influenced the proliferation and attachment of the stem cells.
Article
Medicine, General & Internal
Julian Lommen, Lara Schorn, Christoph Sproll, Norbert R. Kuebler, Luis Fernando Nicolini, Ricarda Merfort, Ayimire Dilimulati, Frank Hildebrand, Majeed Rana, Johannes Greven
Summary: This study evaluated the mechanical fatigue of different polymer plates for mandible reconstruction. The results showed that fiber-reinforced polyetheretherketone, polyetheretherketone, and polyetherketoneketone were able to withstand expected bite forces and had sufficient mechanical strength for mandible reconstruction.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Nadia Karnatz, Henriette L. Moellmann, Max Wilkat, Aida Parviz, Majeed Rana
Summary: The benefit of computer-assisted planning in head and neck surgery has been well-documented. However, the integration of mixed reality systems into clinical settings remains a challenge. This paper presents a novel and user-friendly 3D planning and mixed reality software for head and neck surgery.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Majeed Rana, Henriette L. Moellmann, Lara Schorn, Julian Lommen, Madiha Rana, Max Wilkat, Karsten Hufendiek
Summary: This study demonstrates that a high degree of accuracy can be achieved in the primary reconstruction of complex orbital wall fractures using selective laser melted patient-specific implants (PSIs) and navigation.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Max Wilkat, Karsten Hufendiek, Merve Karahisarlioglu, Maria Borrelli, Christoph Sproll, Majeed Rana
Summary: The proper treatment of two-wall fractured orbits is still a controversial topic, particularly regarding the necessity of medial orbital wall repair. Emerging technologies such as patient-specific implants (PSI) offer reliable and anatomically correct reconstruction options. This study aimed to evaluate the outcome of full orbital reconstruction using PSIs compared to only orbital floor repair using PDS foils, and the results suggest that complex orbital fractures can be reconstructed more accurately with PSI.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Correction
Dentistry, Oral Surgery & Medicine
A. N. Zeller, M. T. Neuhaus, L. V. M. Weissbach, M. Rana, A. Dhawan, F. M. Eckstein, N. C. Gellrich, R. M. Zimmerer
JOURNAL OF MAXILLOFACIAL & ORAL SURGERY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Lara Schorn, Christoph Sproll, Rita Depprich, Norbert R. Kuebler, Majeed Rana, Daman D. Singh, Julian Lommen
Summary: This study evaluated the use of 3D navigation for recovering a dislocated fractured needle. It was found that navigational planning should be conducted immediately before surgery and other tools, such as ultrasound, should also be considered. Additionally, a treatment approach for pandemic crises like COVID-19 was suggested.
CASE REPORTS IN DENTISTRY
(2021)
Article
Oncology
Lara Schorn, Julian Lommen, Rita Depprich, Norbert Kubler, Majeed Rana, Carina Heydt, Philipp Lohneis, Peter Kaiser, Christoph Sproll
MOLECULAR AND CLINICAL ONCOLOGY
(2020)