Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cells

Regulatory T Cells Promote Apelin-Mediated Sprouting Angiogenesis in Type 2 Diabetes

(2018) Oscar M. Leung et al.   Cell Reports

Autoimmune diseases surface after cancer treatment

(2017) Jennifer Couzin-Frankel   SCIENCE

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Regulatory T cells in cancer immunotherapy

(2016) Atsushi Tanaka et al.   CELL RESEARCH

Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice

(2016) Arturo J Vegas et al.   NATURE MEDICINE

TGFβ-dependent expression of PD-1 and PD-L1 controls CD8+ T cell anergy in transplant tolerance

(2016) Marije Baas et al.   eLife

Tetraspanin CD81 Promotes Tumor Growth and Metastasis by Modulating the Functions of T Regulatory and Myeloid-Derived Suppressor Cells

(2015) Felipe Vences-Catalán et al.   CANCER RESEARCH

Tolerance Induction and Reversal of Diabetes in Mice Transplanted with Human Embryonic Stem Cell-Derived Pancreatic Endoderm

(2015) Gregory L. Szot et al.   Cell Stem Cell

Anti–PD-1/PD-L1 therapy of human cancer: past, present, and future

(2015) Lieping Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies

(2015) Steven D Schwartz et al.   LANCET

PD-1/PD-L1 Costimulatory Pathway-induced Mouse Islet Transplantation Immune Tolerance

(2015) T. Li et al.   TRANSPLANTATION PROCEEDINGS

Concise Review: Manufacturing of Pancreatic Endoderm Cells for Clinical Trials in Type 1 Diabetes

(2015) Thomas C. Schulz   Stem Cells Translational Medicine

Insulin-Producing Endocrine Cells Differentiated In Vitro From Human Embryonic Stem Cells Function in Macroencapsulation Devices In Vivo

(2015) Alan D. Agulnick et al.   Stem Cells Translational Medicine

Regulatory T cells influence blood flow recovery in experimental hindlimb ischaemia in an IL-10-dependent manner

(2014) R. Sharir et al.   CARDIOVASCULAR RESEARCH

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

An Effective Approach to Prevent Immune Rejection of Human ESC-Derived Allografts

(2014) Zhili Rong et al.   Cell Stem Cell

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Tolerance induction to human stem cell transplants with extension to their differentiated progeny

(2014) Kathy O. Lui et al.   Nature Communications

Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq experiments with small sample size

(2013) Danni Yu et al.   BIOINFORMATICS

Strength of PD-1 signaling differentially affects T-cell effector functions

(2013) F. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Potent Induction Immunotherapy Promotes Long-Term Insulin Independence After Islet Transplantation in Type 1 Diabetes

(2012) M. D. Bellin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Pluripotent stem cell-based heart regeneration: From the developmental and immunological perspectives

(2012) Kathy O. Lui et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Long-Term Remission of Diabetes in NOD Mice Is Induced by Nondepleting Anti-CD4 and Anti-CD8 Antibodies

(2012) Z. Yi et al.   DIABETES

Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells

(2012) Takahisa Miyao et al.   IMMUNITY

Embryonic stem cell trials for macular degeneration: a preliminary report

(2012) Steven D Schwartz et al.   LANCET

Short-Term Immunosuppression Promotes Engraftment of Embryonic and Induced Pluripotent Stem Cells

(2011) Jeremy I. Pearl et al.   Cell Stem Cell

Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts: Four cases

(2011) G. Basta et al.   DIABETES CARE

Sustained suppression by Foxp3+regulatory T cells is vital for infectious transplantation tolerance

(2011) Adrian R. Kendal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The PDL1-PD1 Axis Converts Human TH1 Cells into Regulatory T Cells

(2011) S. Amarnath et al.   Science Translational Medicine

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

A Role for Regulatory T Cells in Acceptance of ESC-Derived Tissues Transplanted Across an Major Histocompatibility Complex Barrier

(2010) Kathy O. Lui et al.   STEM CELLS

Safety and Viability of Microencapsulated Human Islets Transplanted Into Diabetic Humans

(2009) B. E. Tuch et al.   DIABETES CARE

Insulin use and increased risk of mortality in type 2 diabetes: a cohort study

(2009) J.-M. Gamble et al.   DIABETES OBESITY & METABOLISM

PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV

(2009) Debora Franceschini et al.   JOURNAL OF CLINICAL INVESTIGATION

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

(2009) Loise M. Francisco et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Embryonic Stem Cells: Overcoming the Immunological Barriers to Cell Replacement Therapy

(2009) Kathy Lui et al.   Current Stem Cell Research & Therapy

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Programmed death 1 ligand signaling regulates the generation of adaptive Foxp3+CD4+ regulatory T cells

(2008) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA