Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma

On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies

(2012) Ann-Kristin Petersen et al.   BMC BIOINFORMATICS

Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution But No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits

(2012) Kati Kristiansson et al.   Circulation-Cardiovascular Genetics

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

(2012) Johannes Kettunen et al.   NATURE GENETICS

Mining the Unknown: A Systems Approach to Metabolite Identification Combining Genetic and Metabolic Information

(2012) Jan Krumsiek et al.   PLoS Genetics

Ratio Analysis Nuclear Magnetic Resonance Spectroscopy for Selective Metabolite Identification in Complex Samples

(2011) Siwei Wei et al.   ANALYTICAL CHEMISTRY

Functional glucokinase regulator gene variants have inverse effects on triglyceride and glucose levels, and decrease the risk of obesity in children

(2011) K. Horvatovich et al.   DIABETES & METABOLISM

Genetic associations with lipoprotein subfractions provide information on their biological nature

(2011) Ann-Kristin Petersen et al.   HUMAN MOLECULAR GENETICS

FADS1 Genetic Variability Interacts with Dietary α-Linolenic Acid Intake to Affect Serum Non-HDL–Cholesterol Concentrations in European Adolescents

(2011) Julie Dumont et al.   JOURNAL OF NUTRITION

Human metabolic individuality in biomedical and pharmaceutical research

(2011) Karsten Suhre et al.   NATURE

A genome-wide association study of metabolic traits in human urine

(2011) Karsten Suhre et al.   NATURE GENETICS

A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection

(2011) George Nicholson et al.   PLoS Genetics

Dietary n−3 and n−6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study

(2010) Yingchang Lu et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

An inter-laboratory comparison demonstrates that [1H]-NMR metabolite fingerprinting is a robust technique for collaborative plant metabolomic data collection

(2010) Jane L. Ward et al.   Metabolomics

New loci associated with kidney function and chronic kidney disease

(2010) Anna Köttgen et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Highly variable clinical phenotype of carbamylphosphate synthetase 1 deficiency in one family: an effect of allelic variation in gene expression?

(2009) V Klaus et al.   CLINICAL GENETICS

A genome-wide perspective of genetic variation in human metabolism

(2009) Thomas Illig et al.   NATURE GENETICS

The Common P446L Polymorphism in GCKR Inversely Modulates Fasting Glucose and Triglyceride Levels and Reduces Type 2 Diabetes Risk in the DESIR Prospective General French Population

(2008) M. Vaxillaire et al.   DIABETES

International NMR-Based Environmental Metabolomics Intercomparison Exercise

(2008) Mark R. Viant et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Common variants at 30 loci contribute to polygenic dyslipidemia

(2008) Sekar Kathiresan et al.   NATURE GENETICS

HMDB: a knowledgebase for the human metabolome

(2008) D. S. Wishart et al.   NUCLEIC ACIDS RESEARCH

Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum

(2008) Christian Gieger et al.   PLoS Genetics