Journal
G3-GENES GENOMES GENETICS
Volume 4, Issue 4, Pages 761-767Publisher
GENETICS SOCIETY AMERICA
DOI: 10.1534/g3.113.010140
Keywords
transcription; yeast; inositol; phospholipid synthesis; regulation
Categories
Funding
- National Science Foundation (NSF) [MCB-1020987]
- Summer Program for Undergraduate Research (SPUR) as part of the Northeast Alliance for Graduate Education and the Professoriate Program (NEAGEP) (NSF grant) [0450339]
- National Institutes of Health PREP grant [R25GM086264]
- Direct For Biological Sciences
- Div Of Molecular and Cellular Bioscience [1020987] Funding Source: National Science Foundation
- Direct For Education and Human Resources
- Division Of Human Resource Development [0450339] Funding Source: National Science Foundation
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The overproduction and secretion of inositol (i.e., Opi(-)) phenotype is associated with defects in regulation of phospholipid biosynthesis in yeast. Here we report a screen of the essential yeast gene set using a conditional-expression library. This screen identified novel functions previously unknown to affect phospholipid synthesis.
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