Primary sclerosing cholangitis: a review and update on therapeutic developments

Cordycepin as a sensitizer to tumour necrosis factor (TNF)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-κB

(2012) M. Kadomatsu et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Primary Sclerosing Cholangitis: The Gut-Liver Axis

(2012) James H. Tabibian et al.   Clinical Gastroenterology and Hepatology

Molecular Targets for the Treatment of Fibrosing Cholangiopathies

(2012) L J Maillette de Buy Wenniger et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Fueling fibrosis in chronic hepatitis C

(2012) R. Bataller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The safety and efficacy of oral docosahexaenoic acid supplementation for the treatment of primary sclerosing cholangitis - a pilot study

(2011) C. R. Martin et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Meta-analysis: ursodeoxycholic acid for primary sclerosing cholangitis

(2011) C. K. Triantos et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Pathogenesis of primary sclerosing cholangitis

(2011) Marion J. Pollheimer et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Live donor liver transplantation for primary sclerosing cholangitis: is disease recurrence increased?

(2011) Ivo W Graziadei   CURRENT OPINION IN GASTROENTEROLOGY

Alkaline phosphatase normalization is associated with better prognosis in primary sclerosing cholangitis

(2011) Peter P. Stanich et al.   DIGESTIVE AND LIVER DISEASE

New Treatment Strategies for Primary Sclerosing Cholangitis

(2011) Keith D. Lindor   DIGESTIVE DISEASES

The role of the renin–angiotensin system in liver fibrosis

(2011) M Kamruzzman Munshi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Nuclear Receptors CAR and PXR; therapeutic targets for cholestatic liver disease

(2011) Satoru Kakizaki   Frontiers in Bioscience-Landmark

The Utility of Biomarkers in the Diagnosis and Therapy of Inflammatory Bowel Disease

(2011) James D. Lewis   GASTROENTEROLOGY

Cancer surveillance in patients with primary sclerosing cholangitis

(2011) Nataliya Razumilava et al.   HEPATOLOGY

Inflammatory bowel disease-associated thromboembolism: A systematic review of outcomes with anticoagulation versus catheter-directed thrombolysis

(2011) James H. Tabibian et al.   INFLAMMATORY BOWEL DISEASES

Cholangiocyte N-Ras Protein Mediates Lipopolysaccharide-induced Interleukin 6 Secretion and Proliferation

(2011) Steven P. O'Hara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Safety evaluation of self-expanding metallic biliary stents eluting gemcitabine in a porcine model

(2011) Moon Jae Chung et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Enhanced innate immune responsiveness and intolerance to intestinal endotoxins in human biliary epithelial cells contributes to chronic cholangitis

(2011) Tobias Mueller et al.   LIVER INTERNATIONAL

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Will we ever model PSC? – “It's hard to be a PSC model!”

(2011) Marion J. Pollheimer et al.   Clinics and Research in Hepatology and Gastroenterology

Antibiotics for the Treatment of Primary Sclerosing Cholangitis

(2010) Diaa Aldin H Elfaki et al.   AMERICAN JOURNAL OF THERAPEUTICS

Rapamycin sensitizes Akt inhibition in malignant human breast epithelial cells

(2010) Jie Zheng et al.   CANCER LETTERS

The cholangiographic features of severe forms of ABCB4/MDR3 deficiency-associated cholangiopathy in adults

(2010) R. Poupon et al.   GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE

Endoscopic treatment of postorthotopic liver transplantation anastomotic biliary strictures with maximal stent therapy (with video)

(2010) James H. Tabibian et al.   GASTROINTESTINAL ENDOSCOPY

Bile proteomic profiles differentiate cholangiocarcinoma from primary sclerosing cholangitis and choledocholithiasis

(2010) Tim O. Lankisch et al.   HEPATOLOGY

Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis

(2010) Ling Gu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci

(2010) Espen Melum et al.   NATURE GENETICS

Primary Sclerosing Cholangitis: Meta-Analysis of Diagnostic Performance of MR Cholangiopancreatography

(2010) Maneesh Dave et al.   RADIOLOGY

IgG4+ Plasma Cell Infiltrates in Liver Explants With Primary Sclerosing Cholangitis

(2009) Lizhi Zhang et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Nuclear receptors as therapeutic targets in cholestatic liver diseases

(2009) Gernot Zollner et al.   BRITISH JOURNAL OF PHARMACOLOGY

Gut Homing Receptors on CD8 T Cells Are Retinoic Acid Dependent and Not Maintained by Liver Dendritic or Stellate Cells

(2009) Bertus Eksteen et al.   GASTROENTEROLOGY

Improved Prognosis of Patients With Primary Biliary Cirrhosis That Have a Biochemical Response to Ursodeoxycholic Acid

(2009) Edith M.M. Kuiper et al.   GASTROENTEROLOGY

Endoscopic treatment with multiple stents for post–liver-transplantation nonanastomotic biliary strictures

(2009) James H. Tabibian et al.   GASTROINTESTINAL ENDOSCOPY

Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2−/− mice

(2009) Emina Halilbasic et al.   HEPATOLOGY

Diagnosis and management of primary sclerosing cholangitis

(2009) Roger Chapman et al.   HEPATOLOGY

NFκB p50-CCAAT/Enhancer-binding Protein β (C/EBPβ)-mediated Transcriptional Repression of MicroRNA let-7i following Microbial Infection

(2009) Steven P. O'Hara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EASL Clinical Practice Guidelines: Management of cholestatic liver diseases

(2009)   JOURNAL OF HEPATOLOGY

Long-term Treatment of Primary Sclerosing Cholangitis in Children With Oral Vancomycin: An Immunomodulating Antibiotic

(2009) Yinka K Davies et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

A re-evaluation of the risk factors for the recurrence of primary sclerosing cholangitis in liver allografts

(2009) Edward Alabraba et al.   LIVER TRANSPLANTATION

The immunobiology of primary sclerosing cholangitis

(2009) Jonathan H. Aron et al.   Seminars in Immunopathology

Minocycline in the Treatment of Patients With Primary Sclerosing Cholangitis: Results of a Pilot Study

(2008) Marina G Silveira et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Inhibition of mTOR enhances chemosensitivity in hepatocellular carcinoma

(2008) Ka Ho Tam et al.   CANCER LETTERS

Elastography for Detecting Hepatic Fibrosis: Options and Considerations

(2008) Jayant A. Talwalkar   GASTROENTEROLOGY

A Double-blind, Placebo-controlled, Randomized Study of Infliximab in Primary Sclerosing Cholangitis

(2008) Daan W. Hommes et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Lung Cancer

(2008) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE