The Wnt/β-catenin signaling pathway in liver biology and disease

Organogenesis and Development of the Liver

(2010) Karim Si-Tayeb et al.   DEVELOPMENTAL CELL

Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant β-catenin

(2010) Kari N. Nejak-Bowen et al.   HEPATOLOGY

Conditional β-catenin loss in mice promotes chemical hepatocarcinogenesis: Role of oxidative stress and platelet-derived growth factor receptor α/phosphoinositide 3-kinase signaling

(2010) Xu-Feng Zhang et al.   HEPATOLOGY

Liver-specific β-catenin knockout mice have bile canalicular abnormalities, bile secretory defect, and intrahepatic cholestasis

(2010) Tzu-Hsuan Yeh et al.   HEPATOLOGY

Noncanonical Wnt11 Inhibits Hepatocellular Carcinoma Cell Proliferation and Migration

(2010) T. Toyama et al.   MOLECULAR CANCER RESEARCH

Wnt/β-Catenin Signaling Activates and Determines Hepatic Zonal Expression of Glutathione S-Transferases in Mouse Liver

(2010) Stefanie Giera et al.   TOXICOLOGICAL SCIENCES

A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers

(2010) Olivia M. Lucero et al.   Current Oncology Reports

Wnt/β-catenin signaling in hepatic organogenesis

(2010) Kari Nejak-Bowen et al.   Organogenesis

Hepatic glutamate metabolism: a tale of 2 hepatocytes

(2009) Margaret E Brosnan et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Beta-Catenin Activation Promotes Liver Regeneration after Acetaminophen-Induced Injury

(2009) Udayan Apte et al.   AMERICAN JOURNAL OF PATHOLOGY

Liver-Specific β-Catenin Knockout Mice Exhibit Defective Bile Acid and Cholesterol Homeostasis and Increased Susceptibility to Diet-Induced Steatohepatitis

(2009) Jaideep Behari et al.   AMERICAN JOURNAL OF PATHOLOGY

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

Inducibility of Drug-Metabolizing Enzymes by Xenobiotics in Mice with Liver-Specific Knockout of Ctnnb1

(2009) A. Braeuning et al.   DRUG METABOLISM AND DISPOSITION

Liver Zonation Occurs Through a β-Catenin–Dependent, c-Myc–Independent Mechanism

(2009) Zoé D. Burke et al.   GASTROENTEROLOGY

Mechanisms of Liver Development: Concepts for Understanding Liver Disorders and Design of Novel Therapies

(2009) Frédéric P. Lemaigre   GASTROENTEROLOGY

Convergence of Wnt Signaling on the HNF4α-Driven Transcription in Controlling Liver Zonation

(2009) Marta Colletti et al.   GASTROENTEROLOGY

New school in liver development: Lessons from zebrafish

(2009) Jaime Chu et al.   HEPATOLOGY

β-Catenin Regulates Vitamin C Biosynthesis and Cell Survival in Murine Liver

(2009) Kari N. Nejak-Bowen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Over-expression of glutamine synthetase in focal nodular hyperplasia: a novel easy diagnostic tool in surgical pathology

(2009) Paulette Bioulac-Sage et al.   LIVER INTERNATIONAL

Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells

(2009) Haluk Yuzugullu et al.   Molecular Cancer

Cadherin-Bound β-Catenin Feeds into the Wnt Pathway upon Adherens Junctions Dissociation: Evidence for an Intersection between β-Catenin Pools

(2009) Yoonseok Kam et al.   PLoS One

Roles of Noncanonical Wnt/PCP Pathway Genes in Neuronal Migration and Neurulation in Zebrafish

(2009) Hironori Wada et al.   Zebrafish

Noncanonical Wnt/PCP Signaling During Vertebrate Gastrulation

(2009) Masazumi Tada et al.   Zebrafish

Noncanonical Wnt Signaling in Tumor Progression and Metastasis

(2009) Jason R. Jessen   Zebrafish

Coordinate regulation of human drug-metabolizing enzymes, and conjugate transporters by the Ah receptor, pregnane X receptor and constitutive androstane receptor

(2008) Christoph Köhle et al.   BIOCHEMICAL PHARMACOLOGY

Hepatic Stem-like Phenotype and Interplay of Wnt/β-Catenin and Myc Signaling in Aggressive Childhood Liver Cancer

(2008) Stefano Cairo et al.   CANCER CELL

Wnt Signaling in Liver Cancer

(2008) Yutaka Takigawa et al.   CURRENT DRUG TARGETS

Wnt/β-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology

(2008) Catherine Cavard et al.   Future Oncology

Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene

(2008) Benjamin Cieply et al.   HEPATOLOGY

Knockdown of tight junction protein claudin-2 prevents bile canalicular formation in WIF-B9 cells

(2008) Seiichi Son et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Functional interaction between Wnt3 and Frizzled-7 leads to activation of the Wnt/β-catenin signaling pathway in hepatocellular carcinoma cells

(2008) Miran Kim et al.   JOURNAL OF HEPATOLOGY

The β-catenin pathway is activated in focal nodular hyperplasia but not in cirrhotic FNH-like nodules

(2008) Sandra Rebouissou et al.   JOURNAL OF HEPATOLOGY

Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours

(2008) Sandra Rebouissou et al.   NATURE

Wnt antagonism inhibits hepatic stellate cell activation and liver fibrosis

(2007) Jason H. Cheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY