Inflammation modulation and cardiovascular disease prevention

2012 Update of the Canadian Cardiovascular Society Guidelines for the Diagnosis and Treatment of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult

(2013) Todd J. Anderson et al.   CANADIAN JOURNAL OF CARDIOLOGY

Statins in cardiometabolic disease: what makes pitavastatin different?

(2013) Henry Ginsberg   Cardiovascular Diabetology

HPS2-THRIVE randomized placebo-controlled trial in 25 673 high-risk patients of ER niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment

(2013) et al.   EUROPEAN HEART JOURNAL

Cardiovascular effects of tumour necrosis factor α antagonism in patients with acute myocardial infarction: a first in human study

(2013) Gareth J Padfield et al.   HEART

Immune Effector Mechanisms Implicated in Atherosclerosis: From Mice to Humans

(2013) Peter Libby et al.   IMMUNITY

High-sensitivity C-reactive protein and atherosclerotic disease: From improved risk prediction to risk-guided therapy

(2013) Wolfgang Koenig   INTERNATIONAL JOURNAL OF CARDIOLOGY

Hypercortisolism Is Associated With Increased Coronary Arterial Atherosclerosis: Analysis of Noninvasive Coronary Angiography Using Multidetector Computerized Tomography

(2013) Nicola M. Neary et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis

(2012) Shawn Rose et al.   ANNALS OF THE RHEUMATIC DISEASES

Interleukin 6 destabilizes atherosclerotic plaques by downregulating prolyl-4-hydroxylase α1 via a mitogen-activated protein kinase and c-Jun pathway

(2012) Ke Zhang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Effect of a monoclonal antibody to PCSK9, REGN727/SAR236553, to reduce low-density lipoprotein cholesterol in patients with heterozygous familial hypercholesterolaemia on stable statin dose with or without ezetimibe therapy: a phase 2 randomised controlled trial

(2012) Evan A Stein et al.   LANCET

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

(2012) Benjamin F Voight et al.   LANCET

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

(2012)   LANCET

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

(2012)   LANCET

Interleukin-1β modulates smooth muscle cell phenotype to a distinct inflammatory state relative to PDGF-DD via NF-κB-dependent mechanisms

(2012) Matthew R. Alexander et al.   PHYSIOLOGICAL GENOMICS

The role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study

(2012) Aamer Sandoo et al.   ARTHRITIS RESEARCH & THERAPY

Systematic Review and Meta-Analysis of Methotrexate Use and Risk of Cardiovascular Disease

(2011) Renata Micha et al.   AMERICAN JOURNAL OF CARDIOLOGY

A pilot study of endothelial dysfunction and aortic stiffness after interleukin-6 receptor inhibition in rheumatoid arthritis

(2011) A.D. Protogerou et al.   ATHEROSCLEROSIS

Chronic Inflammatory Diseases and Cardiovascular Risk: A Systematic Review

(2011) Idan Roifman et al.   CANADIAN JOURNAL OF CARDIOLOGY

Clinical trials roundup in idiopathic inflammatory myopathies

(2011) Heřman F. Mann et al.   CURRENT OPINION IN RHEUMATOLOGY

Tocilizumab Monotherapy Reduces Arterial Stiffness as Effectively as Etanercept or Adalimumab Monotherapy in Rheumatoid Arthritis: An Open-label Randomized Controlled Trial

(2011) KENSUKE KUME et al.   JOURNAL OF RHEUMATOLOGY

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Vaccination strategies in atherosclerosis

(2011) Johan Kuiper et al.   THROMBOSIS AND HAEMOSTASIS

Interleukin-1 Blockade With Anakinra to Prevent Adverse Cardiac Remodeling After Acute Myocardial Infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot Study)

(2010) Antonio Abbate et al.   AMERICAN JOURNAL OF CARDIOLOGY

Tumour necrosis factor antagonist use and associated risk reduction of cardiovascular events among patients with rheumatoid arthritis

(2010) J. D. Greenberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Lipoprotein-associated phospholipase A2 and risk of coronary disease, stroke, and mortality: collaborative analysis of 32 prospective studies

(2010)   LANCET

Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis

(2010) Min Jun et al.   LANCET

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Cholesterol Crystals Activate the NLRP3 Inflammasome in Human Macrophages: A Novel Link between Cholesterol Metabolism and Inflammation

(2010) Kristiina Rajamäki et al.   PLoS One

BSR and BHPR rheumatoid arthritis guidelines on safety of anti-TNF therapies

(2010) T. Ding et al.   RHEUMATOLOGY

Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population

(2009) Ruth Frikke-Schmidt   ATHEROSCLEROSIS

Does TNF-alpha blockade play any role in cardiovascular risk among rheumatoid arthritis (RA) patients?

(2009) Raquel Cuchacovich et al.   CLINICAL RHEUMATOLOGY

Major Lipids, Apolipoproteins, and Risk of Vascular Disease

(2009) The Emerging Risk Factors Collaboration*   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The effect of methotrexate on cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review

(2009) S. L. Westlake et al.   RHEUMATOLOGY

Effects of the anti-interleukin-6 receptor antibody, tocilizumab, on serum lipid levels in patients with rheumatoid arthritis

(2009) Shin-ya Kawashiri et al.   RHEUMATOLOGY INTERNATIONAL

Mobile ventricular thrombus arising from the mitral annulus in patients with dense mitral annular calcification

(2009) Ying T. SIA et al.   European Heart Journal-Cardiovascular Imaging

The risk of myocardial infarction and pharmacologic and nonpharmacologic myocardial infarction predictors in rheumatoid arthritis: A cohort and nested case-control analysis

(2008) Frederick Wolfe et al.   ARTHRITIS AND RHEUMATISM

Prospective Study of Inhaled Corticosteroid Use, Cardiovascular Mortality, and All-Cause Mortality in Asthmatic Women

(2008) Carlos A. Camargo et al.   CHEST

Inflammation and Cardiovascular Disease

(2008) William F. Fearon et al.   CIRCULATION

Inhibition of Interleukin-1 by Anakinra Improves Vascular and Left Ventricular Function in Patients With Rheumatoid Arthritis

(2008) Ignatios Ikonomidis et al.   CIRCULATION

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Primer: inflammasomes and interleukin 1β in inflammatory disorders

(2008) Leigh D Church et al.   Nature clinical practice. Rheumatology