- Home
- Publications
- Publication Search
- Publication Details
Title
Role of TET2 Mutations in Myeloproliferative Neoplasms
Authors
Keywords
-
Journal
Current Hematologic Malignancy Reports
Volume 7, Issue 1, Pages 57-64
Publisher
Springer Nature
Online
2011-12-27
DOI
10.1007/s11899-011-0108-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The presence of 5-hydroxymethylcytosine at the gene promoter and not in the gene body negatively regulates gene expression
- (2011) Julia Robertson et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia
- (2011) Y. Shen et al. BLOOD
- CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia
- (2011) H. Makishima et al. BLOOD
- New mutations and pathogenesis of myeloproliferative neoplasms
- (2011) W. Vainchenker et al. BLOOD
- Inhibition of TET2-mediated conversion of 5-methylcytosine to 5-hydroxymethylcytosine disturbs erythroid and granulomonocytic differentiation of human hematopoietic progenitors
- (2011) E. Pronier et al. BLOOD
- Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
- (2011) Z. Li et al. BLOOD
- TET2 mutation is an unfavorable prognostic factor in acute myeloid leukemia patients with intermediate-risk cytogenetics
- (2011) W.-C. Chou et al. BLOOD
- TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis
- (2011) Cyril Quivoron et al. CANCER CELL
- Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation
- (2011) Kelly Moran-Crusio et al. CANCER CELL
- Thymine DNA Glycosylase Is Essential for Active DNA Demethylation by Linked Deamination-Base Excision Repair
- (2011) Salvatore Cortellino et al. CELL
- Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain
- (2011) Junjie U. Guo et al. CELL
- Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells
- (2011) Kian Peng Koh et al. Cell Stem Cell
- TET2Mutations Improve the New European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study
- (2011) Klaus H. Metzeler et al. JOURNAL OF CLINICAL ONCOLOGY
- Myeloproliferative Neoplasms: Molecular Pathophysiology, Essential Clinical Understanding, and Treatment Strategies
- (2011) Ayalew Tefferi et al. JOURNAL OF CLINICAL ONCOLOGY
- Mutation analysis of TET2, IDH1, IDH2 and ASXL1 in chronic myeloid leukemia
- (2011) C Roche-Lestienne et al. LEUKEMIA
- Molecular profiling of chronic myelomonocytic leukemia reveals diverse mutations in >80% of patients with TET2 and EZH2 being of high prognostic relevance
- (2011) V Grossmann et al. LEUKEMIA
- TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
- (2011) Kristine Williams et al. NATURE
- Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
- (2011) William A. Pastor et al. NATURE
- Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
- (2011) Gabriella Ficz et al. NATURE
- Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
- (2011) M. Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
- (2011) S. Ito et al. SCIENCE
- Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells
- (2011) Keith E. Szulwach et al. PLoS Genetics
- 5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells
- (2011) Hume Stroud et al. GENOME BIOLOGY
- Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms
- (2010) F. X. Schaub et al. BLOOD
- Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
- (2010) S. T. Oh et al. BLOOD
- Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value
- (2010) A. E. Smith et al. BLOOD
- Incidence and prognostic value of TET2 alterations in de novo acute myeloid leukemia achieving complete remission
- (2010) O. Nibourel et al. BLOOD
- The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
- (2010) Patrick S. Ward et al. CANCER CELL
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- Genetic Analysis of Transforming Events That Convert Chronic Myeloproliferative Neoplasms to Leukemias
- (2010) O. Abdel-Wahab et al. CANCER RESEARCH
- Chromosomal abnormalities in transformed Ph-negative myeloproliferative neoplasms are associated to the transformation subtype and independent of JAK2 and the TET2 mutations
- (2010) Florence Nguyen-Khac et al. GENES CHROMOSOMES & CANCER
- The role of the JAK2 GGCC haplotype and the TET2 gene in familial myeloproliferative neoplasms
- (2010) D. Olcaydu et al. HAEMATOLOGICA
- Clonal analysis of erythroid progenitors suggests that pegylated interferon α-2a treatment targets JAK2 V617F clones without affecting TET2 mutant cells
- (2010) J-J Kiladjian et al. LEUKEMIA
- Deletions of the transcription factor Ikaros in myeloproliferative neoplasms
- (2010) R Jäger et al. LEUKEMIA
- Mutational analysis inBCR-ABL-negative classic myeloproliferative neoplasms: impact on prognosis and therapeutic choices
- (2010) Ayalew Tefferi LEUKEMIA & LYMPHOMA
- Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
- (2010) Myunggon Ko et al. NATURE
- Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
- (2010) Shinsuke Ito et al. NATURE
- Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
- (2010) Thomas Ernst et al. NATURE GENETICS
- Somatic Mutations ofIDH1andIDH2in the Leukemic Transformation of Myeloproliferative Neoplasms
- (2010) Anthony Green et al. NEW ENGLAND JOURNAL OF MEDICINE
- Recruitment of MBD1 to target genes requires sequence-specific interaction of the MBD domain with methylated DNA
- (2010) Thomas Clouaire et al. NUCLEIC ACIDS RESEARCH
- Examination of the specificity of DNA methylation profiling techniques towards 5-methylcytosine and 5-hydroxymethylcytosine
- (2010) Seung-Gi Jin et al. NUCLEIC ACIDS RESEARCH
- Chronic Myelogenous Leukemia,BCR-ABL1+
- (2009) James W. Vardiman AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Analysis of the Ten-Eleven Translocation 2 (TET2) gene in familial myeloproliferative neoplasms
- (2009) C. Saint-Martin et al. BLOOD
- Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
- (2009) O. Abdel-Wahab et al. BLOOD
- Two routes to leukemic transformation after a JAK2 mutation-positive myeloproliferative neoplasm
- (2009) P. A. Beer et al. BLOOD
- Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms
- (2009) F. H. Grand et al. BLOOD
- The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
- (2009) J. W. Vardiman et al. BLOOD
- Analyses of TET2 mutations in post-myeloproliferative neoplasm acute myeloid leukemias
- (2009) L Couronné et al. LEUKEMIA
- Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates
- (2009) A Tefferi et al. LEUKEMIA
- Mutations of ASXL1 gene in myeloproliferative neoplasms
- (2009) N Carbuccia et al. LEUKEMIA
- TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis
- (2009) A Tefferi et al. LEUKEMIA
- Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
- (2009) A Tefferi et al. LEUKEMIA
- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- (2009) Lenny Dang et al. NATURE
- Acquired mutations in TET2 are common in myelodysplastic syndromes
- (2009) Saskia M C Langemeijer et al. NATURE GENETICS
- Mutation inTET2in Myeloid Cancers
- (2009) François Delhommeau et al. NEW ENGLAND JOURNAL OF MEDICINE
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
- (2009) S. Kriaucionis et al. SCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started