4.1 Article

Magnetophoretic Velocity Determined by Space- and Time-Resolved Extinction Profiles

Journal

IEEE MAGNETICS LETTERS
Volume 6, Issue -, Pages -

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/LMAG.2015.2474306

Keywords

Biomagnetic particles; nanomagnetics; magnetophoretic velocity; nanoobject suspension; extinction profiles

Funding

  1. German Ministry of Economics and Energy (ZIM) [KF 3090401NT2]
  2. German Research Foundation [PL 281/3-1]

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Magnetophoretic velocity of magnetic nano-objects for biomedical applications was characterized by measuring space-and time-resolved extinction profiles (STEP-Technology) using a customized LUMiReader device equipped with a set of permanent magnets (STEP-MAG). The resulting magnetic fields and gradients in a sample volume enable the operator to choose measurement conditions for magnetic micro-and nanoparticles and their assemblies. The dependence of magnetophoretic velocity on concentration and optical wavelengths indicated assembly of the nano-objects upon magnetophoresis. The method has potential applications in biomedicine to develop advanced materials and protocols for cell separation, tissue engineering, and drug/nucleic acid targeting.

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