Drug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1

Transcriptome Sequencing of the Anterior Cingulate in Bipolar Disorder: Dysregulation of G Protein-Coupled Receptors

(2015) Cristiana Cruceanu et al.   AMERICAN JOURNAL OF PSYCHIATRY

Adenosine A2A receptor-mediated control of pilocarpine-induced tremulous jaw movements is Parkinson's disease-associated GPR37 receptor-dependent

(2015) Jorge Gandía et al.   BEHAVIOURAL BRAIN RESEARCH

Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor

(2015) Gina La Sala et al.   FASEB JOURNAL

CASPR2 forms a complex with GPR37 via MUPP1 but not with GPR37(R558Q), an autism spectrum disorder-related mutation

(2015) Yuko Tanabe et al.   JOURNAL OF NEUROCHEMISTRY

The role of parkinson's disease-associated receptor GPR37 in the hippocampus: functional interplay with the adenosinergic system

(2015) João P. Lopes et al.   JOURNAL OF NEUROCHEMISTRY

Endothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12

(2014) J J Maguire et al.   BRITISH JOURNAL OF PHARMACOLOGY

The protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell death

(2014) Priyanka Dutta et al.   JOURNAL OF NEUROCHEMISTRY

A low level of GPR37 is associated with human hepatocellular carcinoma progression and poor patient survival

(2014) Fang Liu et al.   PATHOLOGY RESEARCH AND PRACTICE

The Druggable Genome: Evaluation of Drug Targets in Clinical Trials Suggests Major Shifts in Molecular Class and Indication

(2013) Mathias Rask-Andersen et al.   Annual Review of Pharmacology and Toxicology

Regulation of Fear Responses by Striatal and Extrastriatal Adenosine A2A Receptors in Forebrain

(2013) Catherine J. Wei et al.   BIOLOGICAL PSYCHIATRY

The Concise Guide to PHARMACOLOGY 2013/14: G Protein-Coupled Receptors

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mice lacking the Parkinson's related GPR37/PAEL receptor show non-motor behavioral phenotypes: age and gender effect

(2013) S. Mandillo et al.   GENES BRAIN AND BEHAVIOR

GPR37 Protein Trafficking to the Plasma Membrane Regulated by Prosaposin and GM1 Gangliosides Promotes Cell Viability

(2013) Ebba Gregorsson Lundius et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Parkinson's disease-associated GPR37 receptor-mediated cytotoxicity is controlled by its intracellular cysteine-rich domain

(2013) Jorge Gandía et al.   JOURNAL OF NEUROCHEMISTRY

Precocious cerebellum development and improved motor functions in mice lacking the astrocyte cilium-, patched 1-associated Gpr37l1 receptor

(2013) D. Marazziti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin

(2013) Rebecca C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G protein-linked signaling pathways in bipolar and major depressive disorders

(2013) Hiroaki Tomita et al.   Frontiers in Genetics

Vascular endothelin receptor type B: Structure, function and dysregulation in vascular disease

(2012) Marc Q. Mazzuca et al.   BIOCHEMICAL PHARMACOLOGY

Functional GPR37 trafficking protects against toxicity induced by 6-OHDA, MPP+ or rotenone in a catecholaminergic cell line

(2012) Ebba Gregorsson Lundius et al.   JOURNAL OF NEUROCHEMISTRY

Mutation in Parkinson Disease-Associated, G-Protein-Coupled Receptor 37 (GPR37/PaelR) Is Related to Autism Spectrum Disorder

(2012) Eriko Fujita-Jimbo et al.   PLoS One

Folic acid supplementation dysregulates gene expression in lymphoblastoid cells – Implications in nutrition

(2011) Mohammed A. Junaid et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Absence of the GPR37/PAEL receptor impairs striatal Akt and ERK2 phosphorylation, ΔFosB expression, and conditioned place preference to amphetamine and cocaine

(2011) Daniela Marazziti et al.   FASEB JOURNAL

Extracellular Loop 2 of the Free Fatty Acid Receptor 2 Mediates Allosterism of a Phenylacetamide Ago-Allosteric Modulator

(2011) N. J. Smith et al.   MOLECULAR PHARMACOLOGY

Parkinson's disease tremor: pathophysiology

(2011) Mark Hallett   PARKINSONISM & RELATED DISORDERS

Regulation of Blood Pressure and Salt Homeostasis by Endothelin

(2011) Donald E. Kohan et al.   PHYSIOLOGICAL REVIEWS

Identification of genes related to heart failure using global gene expression profiling of human failing myocardium

(2010) Kyung-Duk Min et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Allostery at G Protein-Coupled Receptor Homo- and Heteromers: Uncharted Pharmacological Landscapes

(2010) N. J. Smith et al.   PHARMACOLOGICAL REVIEWS

Genome-Wide Association Study Identifies GPC5 as a Novel Genetic Locus Protective against Sudden Cardiac Arrest

(2010) Dan E. Arking et al.   PLoS One

GPR37 Surface Expression Enhancement via N-Terminal Truncation or Protein−Protein Interactions

(2009) Jill H. Dunham et al.   BIOCHEMISTRY

Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice

(2009) Junko Ito et al.   CELL AND TISSUE RESEARCH

Induction of macroautophagy by overexpression of the Parkinson’s disease-associated GPR37 receptor

(2009) Daniela Marazziti et al.   FASEB JOURNAL

Anxious and depressive symptoms in Parkinson's disease: The French cross-sectionnal DoPaMiP study

(2009) Laurence Nègre-Pagès et al.   MOVEMENT DISORDERS

Enhancement of the surface expression of G protein-coupled receptors

(2009) Jill H. Dunham et al.   TRENDS IN BIOTECHNOLOGY

Molecular Cytogenetic Analysis and Resequencing of Contactin Associated Protein-Like 2 in Autism Spectrum Disorders

(2008) Betul Bakkaloglu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pael-R transgenic mice crossed with parkin deficient mice displayed progressive and selective catecholaminergic neuronal loss

(2008) Hua-Qin Wang et al.   JOURNAL OF NEUROCHEMISTRY

Structural diversity of G protein-coupled receptors and significance for drug discovery

(2008) Malin C. Lagerström et al.   NATURE REVIEWS DRUG DISCOVERY