Cerebral metabolism following traumatic brain injury: new discoveries with implications for treatment

Endogenous Nutritive Support after Traumatic Brain Injury: Peripheral Lactate Production for Glucose Supply via Gluconeogenesis

(2015) Thomas C. Glenn et al.   JOURNAL OF NEUROTRAUMA

Lactate: Brain Fuel in Human Traumatic Brain Injury: A Comparison with Normal Healthy Control Subjects

(2015) Thomas C. Glenn et al.   JOURNAL OF NEUROTRAUMA

Lactate Clearance Is a Useful Biomarker for the Prediction of All-Cause Mortality in Critically Ill Patients

(2014) Zhongheng Zhang et al.   CRITICAL CARE MEDICINE

Cerebral metabolic effects of exogenous lactate supplementation on the injured human brain

(2014) Pierre Bouzat et al.   INTENSIVE CARE MEDICINE

Cerebral glycolysis: a century of persistent misunderstanding and misconception

(2014) Avital Schurr   Frontiers in Neuroscience

Half-molar sodium lactate infusion to prevent intracranial hypertensive episodes in severe traumatic brain injured patients: a randomized controlled trial

(2013) Carole Ichai et al.   INTENSIVE CARE MEDICINE

Lactate kinetics at the lactate threshold in trained and untrained men

(2013) Laurent A. Messonnier et al.   JOURNAL OF APPLIED PHYSIOLOGY

Direct and indirect lactate oxidation in trained and untrained men

(2013) Chi-An W. Emhoff et al.   JOURNAL OF APPLIED PHYSIOLOGY

Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia

(2013) Raimund I. Herzog et al.   JOURNAL OF CLINICAL INVESTIGATION

Lactate Uptake by the Injured Human Brain: Evidence from an Arteriovenous Gradient and Cerebral Microdialysis Study

(2013) Ibrahim Jalloh et al.   JOURNAL OF NEUROTRAUMA

Nutritional Support for Patients Sustaining Traumatic Brain Injury: A Systematic Review and Meta-Analysis of Prospective Studies

(2013) Xiang Wang et al.   PLoS One

Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier

(2013) A. S. Divakaruni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tight glycemic control increases metabolic distress in traumatic brain injury

(2012) Paul Vespa et al.   CRITICAL CARE MEDICINE

The Neuroprotective Effect of Lactate Is Not Due to Improved Glutamate Uptake after Controlled Cortical Impact in Rats

(2012) Beat Alessandri et al.   JOURNAL OF NEUROTRAUMA

Early Cerebral Metabolic Crisis After TBI Influences Outcome Despite Adequate Hemodynamic Resuscitation

(2012) Nathan R. Stein et al.   Neurocritical Care

Identification and Functional Expression of the Mitochondrial Pyruvate Carrier

(2012) S. Herzig et al.   SCIENCE

A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans

(2012) D. K. Bricker et al.   SCIENCE

Brain Lactate Metabolism in Humans With Subarachnoid Hemorrhage

(2012) Mauro Oddo et al.   STROKE

Pyruvate Protects the Brain Against Ischemia–Reperfusion Injury by Activating the Erythropoietin Signaling Pathway

(2012) Myoung-Gwi Ryou et al.   STROKE

Aerobic production and utilization of lactate satisfy increased energy demands upon neuronal activation in hippocampal slices and provide neuroprotection against oxidative stress

(2012) Schurr   Frontiers in Pharmacology

Transpulmonary pyruvate kinetics

(2011) Matthew L. Johnson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Transpulmonary lactate shuttle

(2011) Matthew L. Johnson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Cerebral ketone metabolism during development and injury

(2011) Mayumi L. Prins   EPILEPSY RESEARCH

In Vivo Evidence for Lactate as a Neuronal Energy Source

(2011) M. T. Wyss et al.   JOURNAL OF NEUROSCIENCE

Early versus Late Parenteral Nutrition in Critically Ill Adults

(2011) Michael P. Casaer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Impact of early parenteral nutrition completing enteral nutrition in adult critically ill patients (EPaNIC trial): a study protocol and statistical analysis plan for a randomized controlled trial

(2011) Michaël P Casaer et al.   Trials

Pyruvate-Enriched Cardioplegia Suppresses Cardiopulmonary Bypass-Induced Myocardial Inflammation

(2010) Myoung-Gwi Ryou et al.   ANNALS OF THORACIC SURGERY

Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass

(2009) Myoung-Gwi Ryou et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The human brain utilizes lactate via the tricarboxylic acid cycle: a 13C-labelled microdialysis and high-resolution nuclear magnetic resonance study

(2009) Clare N. Gallagher et al.   BRAIN

Blood Lactate is an Important Energy Source for the Human Brain

(2009) Gerrit van Hall et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The Effects of Age and Ketogenic Diet on Local Cerebral Metabolic Rates of Glucose after Controlled Cortical Impact Injury in Rats

(2009) Mayumi L. Prins et al.   JOURNAL OF NEUROTRAUMA

Myocardial glucose and lactate metabolism during rest and atrial pacing in humans

(2009) Bryan C. Bergman et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cell-cell and intracellular lactate shuttles

(2009) George A. Brooks   JOURNAL OF PHYSIOLOGY-LONDON

Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc–Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

(2008) Jianxia Guo et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients

(2008) Carole Ichai et al.   INTENSIVE CARE MEDICINE

Lactate: a major and crucial player in normal function of both muscle and brain

(2008) Avital Schurr   JOURNAL OF PHYSIOLOGY-LONDON

Evidence for the Mitochondrial Lactate Oxidation Complex in Rat Neurons: Demonstration of an Essential Component of Brain Lactate Shuttles

(2008) Takeshi Hashimoto et al.   PLoS One

Pyruvate enhances neurological recovery following cardiopulmonary arrest and resuscitation

(2007) Arti B. Sharma et al.   RESUSCITATION