Article
Medicine, General & Internal
Amy S. Paller, Eric L. Simpson, Elaine C. Siegfried, Michael J. Cork, Andreas Wollenberg, Peter D. Arkwright, Weily Soong, Mercedes E. Gonzalez, Lynda C. Schneider, Robert Sidbury, Benjamin Lockshin, Steven Meltzer, Zhixiao Wang, Leda P. Mannent, Nikhil Amin, Yiping Sun, Elizabeth Laws, Bolanle Akinlade, Myles Dillon, Matthew P. Kosloski, Mohamed A. Kamal, Ariane Dubost-Brama, Naimish Patel, David M. Weinreich, George D. Yancopoulos, John T. O'Malley, Ashish Bansal
Summary: This study aimed to evaluate the efficacy and safety of dupilumab with low-potency topical corticosteroids in children aged 6 months to younger than 6 years with moderate-to-severe atopic dermatitis. The results showed that dupilumab significantly improved atopic dermatitis signs and symptoms versus placebo in children younger than 6 years, with well tolerated and acceptable safety profile similar to older children and adults.
Article
Medicine, General & Internal
Flor M. Munoz, Lawrence D. Sher, Charu Sabharwal, Alejandra Gurtman, Xia Xu, Nicholas Kitchin, Stephen Lockhart, Robert Riesenberg, Joanna M. Sexter, Hanna Czajka, Grant C. Paulsen, Yvonne Maldonado, Emmanuel B. Walter, Kawsar R. Talaat, Janet A. Englund, Uzma N. Sarwar, Caitlin Hansen, Martha Iwamoto, Chris Webber, Luke Cunliffe, Benita Ukkonen, Silvina N. Martinez, Barbara A. Pahud, Iona Munjal, Joseph B. Domachowske, Kena A. Swanson, Hua Ma, Kenneth Koury, Susan Mather, Claire Lu, Jing Zou, Xuping Xie, Pei-Yong Shi, David Cooper, Oezlem Tuereci, Ugur Sahin, Kathrin U. Jansen, William C. Gruber
Summary: This study investigated the safety, immunogenicity, and efficacy of the BNT162b2 vaccine in children aged 6 months to 11 years. The results demonstrated that a three-dose series of 3-μg BNT162b2 was safe, immunogenic, and effective in children aged 6 months to 4 years.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Medicine, General & Internal
Nicole Toepfner, Wolfgang C. G. von Meissner, Christoph Strumann, Denisa Drinka, David Stuppe, Maximilian Jorczyk, Jeanne Moor, Johannes Puschel, Melanie Liss, Emilie von Poblotzki, Reinhard Berner, Matthias B. Moor, Cho-Ming Chao
Summary: This retrospective cohort study evaluated the safety of off-label BNT162b2 vaccine use in children younger than 5 years. The study found that the reported symptoms after BNT162b2 administration were comparable to those for non-SARS-CoV-2 vaccines in this age group.
Article
Microbiology
Zhengyi Zhu, Qi Yu, Ganggang Qi, Jufei Yang, Yinghua Ni, Wenhua Ruan, Luo Fang
Summary: This study assessed tooth discoloration in patients <8 years old after exposure to tigecycline, a derivative of tetracycline. It found that two patients developed yellow discoloration. However, due to the small sample size and inadequate follow-up period, the incidence and extent of tigecycline-associated dental adverse events remain unclear.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Medicine, General & Internal
Erika Trapl, Stephanie Pike Moore, Catherine Osborn, Neha Gupta, Thomas E. Love, Tyler G. Kinzy, Audrey Kinsella, Scott Frank
Summary: This study evaluates the association of T21 policy with the prevalence of high school youth tobacco use. The implementation of T21 policy is found to be associated with a decline in youth tobacco use, and it also reduces the disparity among different racial and ethnic groups.
Article
Medicine, General & Internal
Benjamin Koh, Darren Jun Hao Tan, Cheng Han Ng, Clarissa Elysia Fu, Wen Hui Lim, Rebecca Wenling Zeng, Jie Ning Yong, Jia Hong Koh, Nicholas Syn, Wang Meng, Karn Wijarnpreecha, Ken Liu, Choon Seng Chong, Mark Muthiah, Hung N. Luu, Arndt Vogel, Siddharth Singh, Khay Guan Yeoh, Rohit Loomba, Daniel Q. Huang
Summary: Emerging data suggest that the incidence of early-onset cancers is increasing in the US, particularly among females, while decreasing in males. Breast cancer has the highest number of incident cases, but gastrointestinal cancers have the fastest-growing incidence rates among early-onset cancers. These findings are important for developing surveillance strategies and allocating funding priorities.
Letter
Medicine, General & Internal
Michael Fang, Elizabeth Selvin
Summary: This study utilizes 2021 National Health Interview Survey data to investigate the extent to which insulin rationing is prevalent among adults under the age of 65 in the United States, focusing on demographic characteristics.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Medicine, General & Internal
Daniela Penz, Elisabeth Waldmann, Monika Hackl, Lena Jiricka, Lisa-Maria Rockenbauer, Irina Gessl, Jasmin Zessner-Spitzenberg, Arnulf Ferlitsch, Michael Trauner, Monika Ferlitsch
Summary: The incidence of colorectal cancer is increasing among younger adults. This study analyzed data from a national screening colonoscopy registry in Austria to examine the prevalence of precursor lesions and the incidence of colorectal cancer in different age groups. The results showed an increase in the prevalence of adenomas and advanced adenomas in all age groups, while the incidence of colorectal cancer decreased among individuals older than 50 years.
Article
Pediatrics
Eleana Tse, Katerina Plakitsi, Spyridon Voulgaris, George A. Alexiou
Summary: The objective of this pilot study was to determine the effectiveness of teaching first aid to 6-8-year-old children in their primary school. The study aimed to answer two key research questions: (1) Can children in this age group acquire first aid and trauma management skills from their schoolteachers? (2) How long do children retain the acquired first aid knowledge?
Article
Gastroenterology & Hepatology
Dominic King, Tom Thomas, Joht Singh Chandan, Nij Bhala, Nicola J. Adderley, Krishnarajah Nirantharakumar, Nigel Trudgill
Summary: The study indicates that there is an association between achalasia and autoimmune conditions as well as atopic conditions, particularly in patients under 40 years of age. These findings support an autoimmune etiology in achalasia and also suggest a potential atopic etiology, especially in younger subjects.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
R. Edward Hendrick, Mark A. Helvie, Debra L. Monticciolo
Summary: Breast cancer mortality rates among U.S. women have been declining since 1989, but the decline has stopped for women under 40 since 2010. The rapid increase in distant-stage breast cancer rates may be a contributing factor to the change in mortality trends for women under 40.
Review
Medicine, General & Internal
Karina W. Davidson, Michael J. Barry, Carol M. Mangione, Michael Cabana, Aaron B. Caughey, Esa M. Davis, Katrina E. Donahue, Chyke A. Doubeni, Martha Kubik, Li Li, Gbenga Ogedegbe, Lori Pbert, Michael Silverstein, James Stevermer, Chien-Wen Tseng, John B. Wong
Summary: Dental caries is the most common chronic disease in children in the US, with higher prevalence in Mexican American children and non-Hispanic Black children. Early childhood caries can lead to various negative impacts, such as pain, tooth loss, and poor school performance. The US Preventive Services Task Force recommends oral fluoride supplementation and fluoride varnish application for preventing future dental caries in children younger than 5 years.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Letter
Medicine, General & Internal
Sara Y. Tartof, Timothy B. Frankland, Jeff M. Slezak, Laura Puzniak, Bradley K. Ackerson, Luis Jodar, John M. Mclaughlin
Summary: This study investigates the relationship between the administration of wild-type BNT162b2 vaccine and medically attended COVID-19 outcomes in children under the age of 5 in the US.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Medicine, General & Internal
Matthew Castelo, Lawrence Paszat, Bettina E. Hansen, Adena S. Scheer, Neil Faught, Lena Nguyen, Nancy N. Baxter
Summary: This study found no association between the time from presentation to treatment and advanced disease or poor survival in younger adults with colorectal cancer.
Review
Oncology
Sergio M. Lucchini, Agustin Esteban, Mariana A. Nigra, Ana T. Palacios, Juan P. Alzate-Granados, Hernan F. Borla
Summary: A systematic review of 661 patients from 38 studies found that patients with endometrial cancer who underwent hysteroscopic resection followed by progestogens agent treatment had better complete response, higher pregnancy rates, and lower rates of hysterectomies.
GYNECOLOGIC ONCOLOGY
(2021)
Letter
Surgery
Maxime Gignon
PLASTIC AND RECONSTRUCTIVE SURGERY
(2016)
Article
Public, Environmental & Occupational Health
Pascale Lafitte, Michel Bridot, Luis Semedo, Remi Gagnayre
Article
Health Care Sciences & Services
Xavier Gomez-Batiste, Scott A. Murray, Keri Thomas, Carles Blay, Kirsty Boyd, Sebastien Moine, Maxime Gignon, Bart Van den Eynden, Bert Leysen, Johan Wens, Yvonne Engels, Marianne Dees, Massimo Costantini
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT
(2017)
Article
Medicine, General & Internal
Maxime Morsa, Pierre Lombrail, Bernard Boudailliez, Cecile Godot, Vincent Jeantils, Remi Gagnayre
PATIENT PREFERENCE AND ADHERENCE
(2018)
Review
Medicine, General & Internal
O. Jarde, S. Delescluse, T. Yzet, T. Binda, M. Gignon, C. Manaouil
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE
(2019)
Article
Health Care Sciences & Services
Christelle Pennecot, Remi Gagnayre, Christine Ammirati, Eric Bertin, Delphine Capelle, Elisabeth Cheraitia, Gilles Chiniara, Valerie David, Xavier De La Tribonniere, Beatrice Decelle, Philippe Derambure, Maxime Gignon, Catherine Greffier, Olivia Gross, Anne Lalande, Patrick Lartiguet, Claire Letallec, Claude Mahe, Yannette Mero, Roland Mohammed, Benoit Petre, Patricia Picchiottino, Dominique Pougheon-Bertrand, Thierry Secheresse, Genevieve Vaillant, Marie Van der Schueren-Eteve, Jocelyne Verdier, Dalila Benhaberou-Brun, Marc Bardou, Claire Marchand
SIMULATION IN HEALTHCARE-JOURNAL OF THE SOCIETY FOR SIMULATION IN HEALTHCARE
(2020)
Editorial Material
Nursing
Sebastien Colson, Anne Muller, Laurent Visier, Brigitte Vennat, Elisabeth Noel-Hureaux, Remi Gagnayre
JOURNAL OF ADVANCED NURSING
(2021)
Article
Medicine, General & Internal
Benoit Petre, Delphine Kirkove, Vincent de Andrade, Cyril Crozet, Daniela Toro-Arrocet, Aurore Margat, Remi Gagnayre
Summary: During the COVID-19 pandemic, understanding people's behavior changes, the impact of public health measures, and their knowledge, motivations, and beliefs is crucial for adapting management approaches to the crisis.
PATIENT PREFERENCE AND ADHERENCE
(2021)
Article
Health Care Sciences & Services
Maxime Morsa, Amelie Perrin, Valerie David, Gilles Rault, Enora Le Roux, Corinne Alberti, Remi Gagnayre, Dominique Pougheon Bertrand
Summary: This qualitative study aimed to assess the feasibility and appropriate conditions of a new PEx management process by analyzing patients' and CF center teams' experiences regarding education, CD use, and patient-care team relationship during PEx management.
JMIR RESEARCH PROTOCOLS
(2021)
Article
Medicine, General & Internal
Marion Pierson-Marchandise, Sandrine Castelain, Cassandra Chevalier, Etienne Brochot, Jean-Luc Schmit, Momar Diouf, Olivier Ganry, Maxime Gignon
Summary: This study investigated the infection rate of healthcare professionals with SARS-CoV-2 in a University Medical Center in France. Results showed that 9.7% of the professionals were infected. Contact with confirmed cases, age, gender, profession, and symptoms were associated with the infection rate.
News Item
Education, Scientific Disciplines
Julie De Wever, Maxime Gignon, Mathieu Hainselin
Proceedings Paper
Computer Science, Interdisciplinary Applications
Mahmoud Elbattah, Emilien Arnaud, Maxime Gignon, Gilles Dequen
Summary: The implementation of Data Analytics has made significant progress in various domains, with Text Analytics solutions playing a crucial role, particularly in the healthcare sector. The study aims to discuss how healthcare providers can utilize Text Analytics for different purposes and contexts, reviewing key studies published over the past 6 years.
HEALTHINF: PROCEEDINGS OF THE 14TH INTERNATIONAL JOINT CONFERENCE ON BIOMEDICAL ENGINEERING SYSTEMS AND TECHNOLOGIES - VOL. 5: HEALTHINF
(2021)
Proceedings Paper
Computer Science, Artificial Intelligence
Emilien Arnaud, Mahmoud Elbattah, Maxime Gignon, Gilles Dequen
2020 IEEE INTERNATIONAL CONFERENCE ON BIG DATA (BIG DATA)
(2020)
Article
Ergonomics
Maxime Gignon, Carole Amsallem, Christine Ammirati
INTERNATIONAL JOURNAL OF OCCUPATIONAL SAFETY AND ERGONOMICS
(2017)
Article
Education & Educational Research
Thomas Lefevre, Remi Gagnayre, Maxime Gignon
ADVANCES IN HEALTH SCIENCES EDUCATION
(2017)