Article
Economics
Bob G. Schultz, Jessica Tilton, Julie Jun, Tiffany Scott-Horton, Danny Quach, Daniel R. Touchette
Summary: The study investigated the cost-effectiveness of a pharmacist-led MTM clinic compared to no clinic for primary prevention of stroke and cardiovascular disease events in patients with hypertension over 10 years. Results showed that the MTM clinic was cost-effective and suggested the need for new reimbursement models to allow pharmacists to provide cost-effective clinical services.
Article
Pharmacology & Pharmacy
Xikui Lu, Lu Zhang, Hangxing Huang, Xiangping Wu, Zhenting Wang, Ling Huang, Jingyang Li, Huimin Yu, Hongyan Zhang, Jian Xiao
Summary: This study aimed to evaluate the economic advantages of joint management of cancer pain by physicians and pharmacists in clinics from the perspective of the Chinese healthcare system. The results demonstrated that the participation of pharmacists in joint cancer pain clinic services led to improved pain management for patients and showed clear cost-effectiveness advantages.
FRONTIERS IN PHARMACOLOGY
(2023)
Article
Infectious Diseases
Bushra Salman, Amna Al-Hashar, Athar Al-Khirbash, Ibrahim Al-Zakwani
Summary: In 2018, clinical pharmacists' interventions on antimicrobial use at Sultan Qaboos University Hospital in Oman had a positive impact on both clinical and financial outcomes. The most common intervention types were adjusting dosing regimens and deletion of antimicrobial orders.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Medicine, General & Internal
Dave L. Dixon, Karissa Johnston, Julie Patterson, Carlo A. Marra, Ross T. Tsuyuki
Summary: Pharmacist-led interventions can significantly improve blood pressure control, and implementing such interventions in the US may provide high economic value.
Article
Health Care Sciences & Services
Ali Ahmed, Juman Abdulelah Dujaili, Lay Hong Chuah, Furqan Khurshid Hashmi, Long Khanh Dao Le, Zeenat Fatima Chatha, Saval Khanal, Ahmed Awaisu, Nathorn Chaiyakunapruk, Hideo Kato
Summary: This study assesses the cost-effectiveness of pharmacist interventions in HIV care in Pakistan, and finds that involving pharmacists could be a cost-effective approach. The analysis shows that pharmacist intervention increases quality-adjusted life years (QALY) and intervention costs, but the incremental cost-effectiveness ratio (ICER) is well below the recommended threshold. Sensitivity analysis indicates that intervention cost is the most influential parameter affecting the ICER. The study could inform healthcare policies and make pharmacist interventions a regular part of HIV care in Pakistan.
Article
Public, Environmental & Occupational Health
Guillermo Salinas-Escudero, Daniela De la Rosa-Zamboni, Maria Fernanda Carrillo-Vega, Ana Estela Gamino-Arroyo, Filiberto Toledano-Toledano, Fernando Ortega-Riosvelasco, Victor Granados-Garcia, Monica Villa-Guillen, Juan Garduno-Espinosa
Summary: This study evaluated the impact of an automated hand-hygiene monitoring system on HAIs at a pediatric hospital in Mexico and concluded that the AHHMS is a cost-saving alternative, recommending its implementation in other areas of the hospital.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Dina Abushanab, Mounir Atchan, Reem Elajez, Mohamed Elshafei, Ahmed Abdelbari, Moza Al Hail, Palli Valapila Abdulrouf, Wessam El-Kassem, Zanfina Ademi, Abdalla Fadul, Elmustafa Abdalla, Mohammad Issam Diab, Daoud Al-Badriyeh
Summary: This study evaluated the economic impact of interventions initiated by clinical pharmacists in a general tertiary hospital. The results showed that although the pharmacist intervention increased resource use costs, it generated significant economic savings by reducing adverse drug events.
Article
Medicine, General & Internal
John T. Schousboe, Brian L. Sprague, Linn Abraham, Ellen S. O'Meara, Tracy Onega, Shailesh Advani, Louise M. Henderson, Karen J. Wernli, Dongyu Zhang, Diana L. Miglioretti, Dejana Braithwaite, Karla Kerlikowske
Summary: The study found that extending screening mammography to age 80 may have benefits for some women, but the absolute reduction in death rates is small for women with comorbidities. Therefore, women over 75 should weigh the risks and benefits when considering screening mammography.
ANNALS OF INTERNAL MEDICINE
(2022)
Article
Medicine, General & Internal
John T. Schousboe, Brian L. Sprague, Linn Abraham, Ellen S. O'Meara, Tracy Onega, Shailesh Advani, Louise M. Henderson, Karen J. Wernli, Dongyu Zhang, Diana L. Miglioretti, Dejana Braithwaite, Karla Kerlikowske
Summary: Extending mammography screening to age 80 appears to be cost-effective in certain scenarios, but the absolute number of deaths averted is small, especially for women with comorbidities. Women considering screening beyond age 75 should carefully weigh the potential harms of overdiagnosis against the potential benefits of averting breast cancer death.
ANNALS OF INTERNAL MEDICINE
(2022)
Review
Endocrinology & Metabolism
Jiejin Zhu, Ying Zhou, Gang Wang
Summary: Pharmacist involvement in diabetes management is cost-effective compared to standard care, but the reporting quality needs improvement.
Article
Public, Environmental & Occupational Health
Katelyn E. Flaherty, Molly B. Klarman, Youseline Cajusma, Justin Schon, Lerby Exantus, Valery M. Beau de Rochars, Chantale Baril, Torben K. Becker, Eric J. Nelson
Summary: This study compares the costs of nighttime pediatric telemedicine and medication delivery service with hospital emergency care in terms of economic investment and disability-adjusted life years (DALYs). The research findings suggest that the nighttime pediatric telemedicine and medication delivery service could be a cost-effective alternative for pre-emergency conditions in Haiti and similar lower-middle-income countries.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2022)
Article
Pharmacology & Pharmacy
Dina Mohamed Ibrahim, May Ahmed Shawki, Mohamed Hassan Solayman, Nagwa Ali Sabri
Summary: This study evaluated the impact of a clinical pharmacist implemented dispensing protocol on albumin use optimization in an intensive care unit (ICU). The results showed that clinical pharmacist interventions significantly reduced inappropriate albumin use and led to cost savings.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Tingting Qin, Qianying Jin, Xingming Li, Xinyuan Bai, Kun Qiao, Mingyu Gu, Yao Wang
Summary: Comprehensive smoking cessation interventions based in hospitals and communities in China are more cost-effective than pharmacological interventions alone.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Multidisciplinary Sciences
Matej Stuhec, Valentina Tement
Summary: The study found that including a clinical pharmacist in interdisciplinary ward rounds at psychiatric hospitals can significantly reduce both expressed and potential drug-related issues, with a high rate of recommendation acceptance.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Yun-Kyoung Song, Sohyun Jeong, Nayoung Han, Heejin Na, Ha Young Jang, Minji Sohn, Yon Su Kim, Kwon-Wook Joo, Kook-Hwan Oh, Dong Ki Kim, Hajeong Lee, Jung Mi Oh
Summary: The study aimed to analyze the effectiveness of clinical pharmacist services on drug-related problems and patient outcomes in inpatients with chronic kidney disease. Results showed that the pharmacist intervention group had a lower number of DRPs at discharge compared to the control group, indicating the significant role of hospital pharmacists in preventing DRPs and medication discrepancies in CKD inpatients.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Health Care Sciences & Services
Ingrid Sperre Saunes, Karsten Vrangbek, Haldor Byrkjeflot, Signe Smith Jervelund, Hans Okkels Birk, Liina-Kaisa Tynkkynen, Ilmo Keskimaki, Sigurbjorg Sigurgeirsdottir, Nils Janlov, Joakim Ramsberg, Cristina Hernandez-Quevedo, Sherry Merkur, Anna Sagan, Marina Karanikolos
Summary: This paper explores and compares health system responses to the COVID-19 pandemic in Denmark, Finland, Iceland, Norway, and Sweden. The findings suggest differences in implementation and outcomes despite similar policy measures adopted by these countries. Factors such as migrant populations and working conditions may play a role in the variations in outcomes. Additionally, the paper highlights the potential impact of the COVID-19 epidemic on legislation and governance principles in the Nordic countries.
Review
Cardiac & Cardiovascular Systems
Niklas Bergh, Anna Myredal, Per Nivedahl, Max Petzold, Sultan Zarin, Constanze Wartenberg, Susanna M. Wallerstedt
Summary: This review compares the efficacy and safety of clopidogrel and ticagrelor as part of dual antiplatelet therapy in patients with acute coronary syndrome and older patients. The results show that there is little or no difference in all-cause mortality between the two drugs. Although not evident in older patients, it cannot be excluded that clopidogrel may be slightly less efficient in reducing the risk of cardiovascular mortality and myocardial infarction, whereas ticagrelor is probably more efficacious in reducing the risk of stent thrombosis. Clopidogrel results in a reduced risk of dyspnea and clinically significant bleeding, and in older people probably in a reduced risk of major bleeding.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
(2022)
Article
Pharmacology & Pharmacy
Carina Tukukino, Naldy Parodi Lopez, Staffan A. Svensson, Susanna M. Wallerstedt
Summary: This study described the interaction alerts in older patients and evaluated whether these alerts required further medical action or had already been addressed. The results showed that most alerts had already been addressed or were not relevant in the clinical setting, but some patients still needed medical action.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Pharmacology & Pharmacy
Naldy Parodi Lopez, Staffan A. Svensson, Susanna M. Wallerstedt
Summary: This study investigates the clinical relevance of potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs), and finds that a fraction of them are clinically relevant. The study shows that the number of PIMs/PPOs and the number of drugs are associated with inadequate drug treatment.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Pharmacology & Pharmacy
Helena Sundvall, Sigurd Vitols, Susanna M. Wallerstedt, Johan Fastbom
Summary: The prevalence and initiation of statin therapy are increasing among the oldest old, despite the lack of randomized controlled trials focusing on this age group and the difficulty in detecting safety signals.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Article
Pharmacology & Pharmacy
Naldy Parodi Lopez, Bjorn Belfrage, Anders Koldestam, Johan Lonnbro, Staffan A. Svensson, Susanna M. Wallerstedt
Summary: This study aimed to revisit the inter-rater reliability of drug treatment assessments according to the STOPP/START criteria. The findings showed issues with reliability and highlighted methodological factors that may contribute to inconsistency.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Medicine, General & Internal
Susanna M. Wallerstedt, Staffan A. Svensson, Johan Lonnbro, Fredrik Hieronymus, Johan Fastbom, Mikael Hoffmann, Naldy Parodi Lopez
Summary: In this diagnostic study, the evaluated PIM/PPO sets had poor to fair performance as diagnostic tools to identify inadequate drug treatment, suggesting the need for reconsideration of using PIMs/PPOs as indicators of drug treatment quality.
Article
Pharmacology & Pharmacy
Carina Tukukino, Anna L. Eriksson, Walaa Hamdan, Frida Wallin Hybelius, Susanna M. Wallerstedt
Summary: Classifications of drug interaction alerts vary between knowledge resources, but there is limited exploration of agreement in recommendations for clinical management. A study analyzed medication lists of 274 older patients and found that while many drug pairs triggered alerts of similar significance in different resources, the recommendations provided varied considerably. The findings highlight the need for medical and pharmaceutical reflection on prescribing decisions as the recommendations cannot be considered definitive.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
(2023)
Article
Pharmacology & Pharmacy
Pia Seidel, Bo Rolander, Anna L. Eriksson, Ulf Lindahl, Susanna M. Wallerstedt, Staffan Haegg, Anders Kling
Summary: This study aimed to investigate the use of drug information by physicians in their professional work, particularly those working in primary care. A web-based questionnaire was distributed to physicians in Sweden, addressing drug-related queries, sources used, and factors influencing source choice. The study found that physicians frequently use drug information sources, especially those in primary care. Credibility and easy access were key factors influencing source choice, and personal characteristics also influenced the choice of drug information sources in primary care.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Article
Clinical Neurology
Daniel von Below, Susanna M. Wallerstedt, Filip Bergquist
Summary: This study aimed to validate the Patient-Reported Outcomes in Parkinson's Disease (PRO-PD) scale for monitoring symptoms in PD patients. The results showed that PRO-PD exhibited good reliability and validity in monitoring symptoms in a representative sample of outpatients with PD.
MOVEMENT DISORDERS
(2023)
Meeting Abstract
Public, Environmental & Occupational Health
Staffan A. Svensson, Carina Tukukino, Naldy Parodi Lopez, Susanna M. Wallerstedt
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2022)
Meeting Abstract
Public, Environmental & Occupational Health
Carina Tukukino, Walaa Hamdan, Frida Wallin Hybelius, Anna L. Eriksson, Susanna M. Wallerstedt
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2022)
Meeting Abstract
Public, Environmental & Occupational Health
Susanna M. Wallerstedt, Johan Lonnbro, Staffan A. Svensson, Fredrik Hieronymus, Johan Fastbom, Mikael Hoffmann, Naldy Parodi Lopez
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2022)
Meeting Abstract
Public, Environmental & Occupational Health
Johan Lonnbro, Lina Holmqvist, Elisabeth Persson, Per Thyzell, N. David Aberg, Susanna M. Wallerstedt
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2022)
Meeting Abstract
Public, Environmental & Occupational Health
Naldy Parodi Lopez, Staffan A. Svensson, Susanna M. Wallerstedt
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
(2022)