Molecular and cellular development of spinal cord locomotor circuitry

Probing diversity within subpopulations of locomotor-related V0 interneurons

(2015) Anna Griener et al.   Developmental Neurobiology

Sim1is required for the migration and axonal projections of V3 interneurons in the developing mouse spinal cord

(2015) Jake Blacklaws et al.   Developmental Neurobiology

Msx1 and Msx2 act as essential activators of Atoh1 expression in the murine spinal cord

(2014) N. Duval et al.   DEVELOPMENT

Different combinations of Notch ligands and receptors regulate V2 interneuron progenitor proliferation and V2a/V2b cell fate determination

(2014) Sayumi Okigawa et al.   DEVELOPMENTAL BIOLOGY

Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord

(2014) Min Zou et al.   DEVELOPMENTAL DYNAMICS

Genetic dissection of Gata2 selective functions during specification of V2 interneurons in the developing spinal cord

(2014) Cédric Francius et al.   Developmental Neurobiology

Sox5 controls dorsal progenitor and interneuron specification in the spinal cord

(2014) Alejandra C. Quiroga et al.   Developmental Neurobiology

V1 and V2b Interneurons Secure the Alternating Flexor-Extensor Motor Activity Mice Require for Limbed Locomotion

(2014) Jingming Zhang et al.   NEURON

Motor Axon Synapses on Renshaw Cells Contain Higher Levels of Aspartate than Glutamate

(2014) Dannette S. Richards et al.   PLoS One

Olig3 Is Not Involved in the Ventral Patterning of Spinal Cord

(2014) Zijing Liu et al.   PLoS One

Dorsally derived spinal interneurons in locomotor circuits

(2013) Anna Vallstedt et al.   Annals of the New York Academy of Sciences

Functional Subpopulations of V3 Interneurons in the Mature Mouse Spinal Cord

(2013) J. Borowska et al.   JOURNAL OF NEUROSCIENCE

Circuits for Grasping: Spinal dI3 Interneurons Mediate Cutaneous Control of Motor Behavior

(2013) Tuan V. Bui et al.   NEURON

Identification of Multiple Subsets of Ventral Interneurons and Differential Distribution along the Rostrocaudal Axis of the Developing Spinal Cord

(2013) Cédric Francius et al.   PLoS One

BMP-Smad 1/5/8 signalling in the development of the nervous system

(2013) Shane V. Hegarty et al.   PROGRESS IN NEUROBIOLOGY

The E3 Ligase Mind Bomb-1 (Mib1) Modulates Delta-Notch Signaling to Control Neurogenesis and Gliogenesis in the Developing Spinal Cord

(2012) Kyungjoon Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional characterization of dI6 interneurons in the neonatal mouse spinal cord

(2012) Jason Dyck et al.   JOURNAL OF NEUROPHYSIOLOGY

Renshaw Cells and Ia Inhibitory Interneurons Are Generated at Different Times from p1 Progenitors and Differentiate Shortly after Exiting the Cell Cycle

(2012) A. Benito-Gonzalez et al.   JOURNAL OF NEUROSCIENCE

Wnt7A Identifies Embryonic  -Motor Neurons and Reveals Early Postnatal Dependence of  -Motor Neurons on a Muscle Spindle-Derived Signal

(2012) S. Ashrafi et al.   JOURNAL OF NEUROSCIENCE

Mutations in DMRT3 affect locomotion in horses and spinal circuit function in mice

(2012) Lisa S. Andersson et al.   NATURE

SnapShot: Spinal Cord Development

(2011) William A. Alaynick et al.   CELL

Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program

(2011) F. J. Stam et al.   DEVELOPMENT

Canonical BMP7 activity is required for the generation of discrete neuronal populations in the dorsal spinal cord

(2011) G. Le Dreau et al.   DEVELOPMENT

Regulation of spinal interneuron development by the Olig-related protein Bhlhb5 and Notch signaling

(2011) K. Skaggs et al.   DEVELOPMENT

Functional organization of V2a-related locomotor circuits in the rodent spinal cord

(2010) Kimberly J. Dougherty et al.   Annals of the New York Academy of Sciences

The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance

(2010) A. Holz et al.   DEVELOPMENT

A Cre transgenic line for studying V2 neuronal lineages and functions in the spinal cord

(2010) Shengguo Li et al.   GENESIS

Motor and Dorsal Root Ganglion Axons Serve as Choice Points for the Ipsilateral Turning of dI3 Axons

(2010) O. Avraham et al.   JOURNAL OF NEUROSCIENCE

Sox1 Is Required for the Specification of a Novel p2-Derived Interneuron Subtype in the Mouse Ventral Spinal Cord

(2010) H. Panayi et al.   JOURNAL OF NEUROSCIENCE

Electrophysiological Characterization of V2a Interneurons and Their Locomotor-Related Activity in the Neonatal Mouse Spinal Cord

(2010) G. Zhong et al.   JOURNAL OF NEUROSCIENCE

Firing and Cellular Properties of V2a Interneurons in the Rodent Spinal Cord

(2010) K. J. Dougherty et al.   JOURNAL OF NEUROSCIENCE

Global Control of Motor Neuron Topography Mediated by the Repressive Actions of a Single Hox Gene

(2010) Heekyung Jung et al.   NEURON

Monosynaptic Rabies Virus Reveals Premotor Network Organization and Synaptic Specificity of Cholinergic Partition Cells

(2010) Anna E. Stepien et al.   NEURON

Two Notch Ligands, Dll1 and Jag1, Are Differently Restricted in Their Range of Action to Control Neurogenesis in the Mammalian Spinal Cord

(2010) Catarina Ramos et al.   PLoS One

Measured motion: searching for simplicity in spinal locomotor networks

(2009) Sten Grillner et al.   CURRENT OPINION IN NEUROBIOLOGY

Neurog2 is a direct downstream target of the Ptf1a-Rbpj transcription complex in dorsal spinal cord

(2009) R. M. Henke et al.   DEVELOPMENT

Restricted patterns of Hoxd10 and Hoxd11 set segmental differences in motoneuron subtype complement in the lumbosacral spinal cord

(2009) Mala Misra et al.   DEVELOPMENTAL BIOLOGY

Activity of Hb9 Interneurons during Fictive Locomotion in Mouse Spinal Cord

(2009) A. C. Kwan et al.   JOURNAL OF NEUROSCIENCE

Multiple Transcriptional Mechanisms Control Ptf1a Levels during Neural Development Including Autoregulation by the PTF1-J Complex

(2009) D. M. Meredith et al.   JOURNAL OF NEUROSCIENCE

In Mice Lacking V2a Interneurons, Gait Depends on Speed of Locomotion

(2009) S. A. Crone et al.   JOURNAL OF NEUROSCIENCE

Circuits controlling vertebrate locomotion: moving in a new direction

(2009) Martyn Goulding   NATURE REVIEWS NEUROSCIENCE

Transcriptional control of axonal guidance and sorting in dorsal interneurons by the Lim-HD proteins Lhx9 and Lhx1

(2009) Oshri Avraham et al.   Neural Development

Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival

(2009) Neil A Shneider et al.   Neural Development

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

A Cluster of Cholinergic Premotor Interneurons Modulates Mouse Locomotor Activity

(2009) Laskaro Zagoraiou et al.   NEURON

Characterization of Foxp2-expressing cells in the developing spinal cord

(2009) Y. Morikawa et al.   NEUROSCIENCE

Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development

(2009) C. Francius et al.   NEUROSCIENCE

Gamma and alpha motor neurons distinguished by expression of transcription factor Err3

(2009) A. Friese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hox Repertoires for Motor Neuron Diversity and Connectivity Gated by a Single Accessory Factor, FoxP1

(2008) Jeremy S. Dasen et al.   CELL

V2a and V2b neurons are generated by the final divisions of pair-producing progenitors in the zebrafish spinal cord

(2008) Y. Kimura et al.   DEVELOPMENT

Identification and subclassification of new Atoh1 derived cell populations during mouse spinal cord development

(2008) George R. Miesegaes et al.   DEVELOPMENTAL BIOLOGY

A Regulatory Network to Segregate the Identity of Neuronal Subtypes

(2008) Seunghee Lee et al.   DEVELOPMENTAL CELL

Early Postnatal Development of Reciprocal Ia Inhibition in the Murine Spinal Cord

(2008) Zhi Wang et al.   JOURNAL OF NEUROPHYSIOLOGY

The Neurotrophic Effects of Glial Cell Line-Derived Neurotrophic Factor on Spinal Motoneurons Are Restricted to Fusimotor Subtypes

(2008) T. W. Gould et al.   JOURNAL OF NEUROSCIENCE

Continuous shifts in the active set of spinal interneurons during changes in locomotor speed

(2008) David L McLean et al.   NATURE NEUROSCIENCE

Early Motor Neuron Pool Identity and Muscle Nerve Trajectory Defined by Postmitotic Restrictions in Nkx6.1 Activity

(2008) Natalia V. De Marco Garcia et al.   NEURON

Probing the Locomotor Conundrum: Descending the ‘V’ Interneuron Ladder

(2008) Anna E. Stepien et al.   NEURON

A Molecular Program for Contralateral Trajectory: Rig-1 Control by LIM Homeodomain Transcription Factors

(2008) Sara I. Wilson et al.   NEURON

Genetic Ablation of V2a Ipsilateral Interneurons Disrupts Left-Right Locomotor Coordination in Mammalian Spinal Cord

(2008) Steven A. Crone et al.   NEURON

V3 Spinal Neurons Establish a Robust and Balanced Locomotor Rhythm during Walking

(2008) Ying Zhang et al.   NEURON