Article
Dentistry, Oral Surgery & Medicine
Aaron N. Colamarino, Thomas M. Johnson, Daniel M. Boudreaux, Joseph M. Dutner, Brian W. Stancoven, Adam R. Lincicum, Joshua A. Akers
Summary: This study evaluated the influence of probiotic bacteria supplementation, along with prebiotic inulin, on biofilm composition using an ex vivo model. The results showed that inulin supplementation increased the relative abundances of Lactobacillus and Bifidobacterium species, while decreasing the abundances of Streptococcus, Veillonella, Fusobacterium, Parvimonas, and Prevotella species. Inoculation with L. reuteri or B. animalis subsp. lactis only increased the relative abundance of the supplemented probiotic genera. Additionally, inulin supplementation led to decreased biofilm diversity.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Ying-Wu Chen, Ming-Lun Lee, Cheng-Yang Chiang, Earl Fu
Summary: This study examined the effects of Bifidobacterium and Lactobacillus on periodontitis using a rat model. The results showed that the combination of these probiotics enhanced IL-10 levels and ameliorated the symptoms of periodontitis. Single-use of probiotics also had some alleviating effects.
JOURNAL OF DENTAL SCIENCES
(2023)
Article
Pharmacology & Pharmacy
Natali Shimabukuro, Amalia C. de S. Cataruci, Karin H. Ishikawa, Bruna E. de Oliveira, Dione Kawamoto, Ellen S. Ando-Suguimoto, Emmanuel Albuquerque-Souza, Jacques R. Nicoli, Caroline M. Ferreira, Jean de Lima, Manuela R. Bueno, Leandro B. R. da Silva, Pedro H. F. Silva, Michel R. Messora, Niels O. S. Camara, Maria Regina L. Simionato, Marcia P. A. Mayer
Summary: Bifidobacterium can control periodontitis by modulating immune response and bone destruction, with B. bifidum 162(2A) being more effective than B. breve 110(1A). Both strains showed different effects in the mouse model, with B. bifidum 162(2A) demonstrating potential in controlling periodontitis.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Dentistry, Oral Surgery & Medicine
Andre L. G. Moreira, Giselle A. Silva, Pedro H. F. Silva, Sergio L. Salvador, Raphael M. Vicente, Graziele C. Ferreira, Jose E. Tanus-Santos, Marcia P. A. Mayer, Karin H. Ishikawa, Sergio Luis Scombatti de Souza, Flavia A. C. Furlaneto, Michel R. Messora
Summary: This study found that Bifidobacterium animalis subspecies lactis HN019 can reduce the sequelae of experimental periodontitis in rats by modulating systemic parameters. Bifidobacterium lactis HN019 can decrease dyslipidemia, insulin resistance, proteinuria levels, systolic blood pressure, hepatic steatosis, and expression of adipokines, as well as improve intestinal microbiota imbalance and prevent alveolar bone loss. These findings highlight the importance of Bifidobacterium lactis HN019 in preventing the damage caused by periodontitis.
JOURNAL OF PERIODONTAL RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Luciana Prado Maia, Yara Loyanne de Almeida Silva Levi, Pedro Henrique Felix Silva, Luana Carla Wons, Livia Pizzo Pitelli, Jessica Goulart de Castro, Eder da Silva Dolens, Danielle Gregorio, Fabiana Gouveia Straioto, Carolina dos Santos Santinoni, Renato Casarin, Edilson Ervolino, Flavia Aparecida Chaves Furlaneto, Michel Reis Messora
Summary: This study evaluated the effects of the probiotic Bifidobacterium animalis subsp. lactis HN019 (HN019) on the development of experimental periodontitis in rats submitted to chemotherapy. The results showed that the EP-5FU-HN019 group had less bone and connective tissue loss compared to the EP-5FU group, while the EP-HN019 and EP-5FU-HN019 groups had greater bone volume than the EP and EP-5FU groups, respectively. Probiotic therapy also led to an increase in the proportions of B. lactis in the feces and reduced the expression of periodontopathogens in the biofilm of rats submitted to chemotherapy.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Nutrition & Dietetics
Su-Jin Jung, Ji-Hyun Hwang, Eun-Ock Park, Seung-Ok Lee, Yun-Jo Chung, Myung-Jun Chung, Sanghyun Lim, Tae-Joong Lim, Yunhi Ha, Byung-Hyun Park, Soo-Wan Chae
Summary: Excessive alcohol consumption is a significant cause of morbidity and mortality worldwide. This study investigated the effects of a probiotic mixture on alcohol and acetaldehyde metabolism, finding that probiotic supplementation can significantly downregulate the blood levels of alcohol and acetaldehyde in individuals with a specific ALDH2 genotype. However, there were no significant improvements in hangover symptoms between the probiotic and placebo groups.
Article
Dentistry, Oral Surgery & Medicine
Davi N. A. Silva, Natalia T. S. Cruz, Agnes A. Martins, Regia C. M. Silva, Hursula C. Almeida, Heloisa E. S. Costa, Karina M. O. Santos, Basilio R. Vieira, Frederico B. Sousa, S. Junior Francisco, Raimundo F. A. Junior, Gerlane C. B. Guerra, Flavia Q. Pirih, Aurigena A. Araujo, Ana R. L. A. Martins
Summary: This study evaluated the antihyperglycemic, anti-bone-resorptive, and anti-inflammatory efficacy of the probiotic Lactobacillus rhamnosus EM1107 in an experimental model of ligature-induced periodontitis in diabetic rats treated with metformin. The results showed that Lactobacillus significantly reduced IL-1 beta and TNF-alpha levels, decreased blood glucose levels, and alleviated inflammation and bone loss. This suggests that Lactobacillus has immunoinflammatory effects in type 1 diabetes mellitus associated with periodontitis.
JOURNAL OF PERIODONTOLOGY
(2023)
Review
Nutrition & Dietetics
Minghui Sun, Jing Luo, Hanmei Liu, Yue Xi, Qian Lin
Summary: The mixed strain of Lactobacillus and Bifidobacterium can effectively prevent eczema in infants under three years old, regardless of family history. Factors such as probiotic dosage and timing of intervention also play a role in the preventive effects.
Article
Nutrition & Dietetics
Jui-Fen Chen, Mei-Chen Ou-Yang, Ko-Chiang Hsia, Ching-Min Li, Yao-Tsung Yeh, Hsieh-Hsun Ho
Summary: This study examined the safety of long-term oral administration of L. salivarius AP-32 and B. animalis CP-9 in healthy infants and found that they have a positive impact on the maintenance of a healthy gut flora. The use of L. salivarius AP-32 or B. animalis CP-9 for infants from 7 days to 6 months of age is safe.
Article
Dentistry, Oral Surgery & Medicine
Hafize Ozturk Ozener, Leyla Kuru, Tanju Kadir, Bahar Kuru
Summary: The objective of this study was to investigate the clinical and microbiological effects of Bifidobacterium animalis subsp. lactis DN-173010 containing yogurt as an adjunct to non-surgical periodontal treatment in periodontitis patients. The results showed that the test group, which consumed the yogurt with Bifidobacterium animalis subsp. lactis DN-173010, had significant improvements in plaque index, gingival index, and bleeding on probing compared to the control group. However, there were no significant differences in probing depth and clinical attachment level changes between the study groups.
CLINICAL ORAL INVESTIGATIONS
(2023)
Article
Immunology
Longxian Lv, Deguang Mu, Yiling Du, Ren Yan, Huiyong Jiang
Summary: CBLEB treatment alleviates cyclophosphamide-induced immunosuppression and dysbiosis of gut microbiota, corrects alterations in metabolome profiles, and induces recovery of altered carbohydrate metabolism and signal transduction pathways. The study provides a basis for utilizing CBLEB in the treatment of immunodeficiency.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Food Science & Technology
Yukyung Choi, Eunyoung Park, Sejeong Kim, Jimyeong Ha, Hyemin Oh, Yujin Kim, Yewon Lee, Yeongeun Seo, Joohyun Kang, Soomin Lee, Heeyoung Lee, Yohan Yoon, Kyoung-Hee Choi
Summary: The study focused on the effects of Lactobacillus curvatus SMFM2016-NK on periodontal disease, noting its ability to alleviate tissue damage, decrease osteoclast cells, and increase osteoblast cells. Additionally, the probiotic was found to alter the composition of gut microbiome and was deemed safe for consumption, suggesting it as a beneficial probiotic for alleviating symptoms of periodontal disease.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Review
Food Science & Technology
Yue Xiao, Qixiao Zhai, Hao Zhang, Wei Chen, Colin Hill
Summary: Lactobacillus and Bifidobacterium colonization in the gut is influenced by various factors, including species and strain specificity, natural history, genomic adaptability, metabolic interactions, microbiome structure, host genotype, diet, and host-microbe coadaptation. Under these influences, a customized colonization can be achieved through a machine learning prediction model.
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 12, 2021
(2021)
Article
Agriculture, Multidisciplinary
Meng-Xin Hu, Fei He, Ya-Xin Guo, Li-Zhen Mo, Xuan Zhu
Summary: This study compares the differences between probiotic biofilms and planktonic cells in pathogen inhibition and microbiota remodeling. The results show that probiotic biofilms are more effective in modulating the microbiota and producing short-chain fatty acids than planktonic cells.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Irina-Georgeta Sufaru, Luminita Lazar, Dorina-Cerasella Sincar, Maria-Alexandra Martu, Liliana Pasarin, Elena-Odette Luca, Ada Stefanescu, Eliza-Maria Froicu, Sorina-Mihaela Solomon
Summary: This study evaluated the clinical effects of L.reuteri DSM 17938 as an adjunctive therapy and found that it significantly improved the clinical parameters of severe periodontitis patients.
APPLIED SCIENCES-BASEL
(2022)