Article
Infectious Diseases
Benjamin Perlitz, Anna Slagman, Jennifer Hitzek, Dorothee Riedlinger, Martin Moeckel
Summary: The study shows that using point-of-care PCR testing in the emergency department can reduce staff sick days, improve diagnostic and therapeutic procedures, provide more timely and effective treatment options, especially for patients with respiratory symptoms. Patients with on-site testing were more frequently treated with antibiotics and transferred to external hospitals.
INFLUENZA AND OTHER RESPIRATORY VIRUSES
(2021)
Review
Pathology
Larissa May, Nam Tran, Nathan A. Ledeboer
Summary: Despite advances in SARS-CoV-2 point-of-care testing, challenges remain in implementing these technologies in the emergency department. A shift in paradigm is necessary to enhance diagnosis and clinical outcomes.
EXPERT REVIEW OF MOLECULAR DIAGNOSTICS
(2021)
Article
Medicine, Research & Experimental
Eugenia-Maria Muresan, Adela Golea, Stefan Cristian Vesa, Manuela Lenghel, Csaba Csutak, Lacramioara Perju-Dumbrava
Summary: Spontaneous intracerebral hemorrhage (sICH) is associated with high morbidity and mortality rates. This study investigated the relationship between emergency department point-of-care blood biomarkers and day 90 functional outcome in patients with acute sICH. The results showed that admission D-dimer levels were associated with functional outcome, severity, and early neurological worsening.
EXPERIMENTAL AND THERAPEUTIC MEDICINE
(2022)
Article
Medical Laboratory Technology
Vitali Koch, Christian Booz, Leon D. Gruenewald, Moritz H. Albrecht, Tatjana Gruber-Rouh, Katrin Eichler, Ibrahim Yel, Scherwin Mahmoudi, Jan-Erik Scholtz, Simon S. Martin, Christiana Graf, Thomas J. Vogl, Christophe Weber, Stefan E. Hardt, Norbert Frey, Evangelos Giannitsis
Summary: The study assessed the performance of D-dimer testing for ACS diagnosis and prediction of MI outcomes. The results showed that D-dimer concentrations were significantly different in patients with different levels of hs-cTnT. Higher D-dimer levels were associated with an increased risk of recurrent MI and all-cause mortality. D-dimer was an independent predictor of all-cause mortality and subsequent MI events. However, D-dimer did not significantly improve diagnostic performance unless values exceeded the 95th percentile.
CLINICAL BIOCHEMISTRY
(2022)
Review
Hematology
David A. Fitzmaurice, Geert-Jan Geersing, Xavier Armoiry, Sam Machin, Steve Kitchen, Ian Mackie
Summary: This guideline, written on behalf of ICSH, focuses on two point of care haematology tests, INR and D-dimer, used in primary care settings. The recommendations are based on published literature and expert opinions and should supplement regional requirements and standards.
INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY
(2023)
Article
Geriatrics & Gerontology
Elizabeth Kunkel, Peter Tanuseputro, Amy Hsu, Robert Talarico, Julie Lapenskie, Samantha Calder-Sprackman, Daniel Kobewka
Summary: Rapid access to diagnostic testing and IV therapy in long-term care facilities has been found to reduce potentially preventable emergency department visits, suggesting that improving access to these resources may help residents stay at home rather than seeking ED care.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2021)
Article
Medicine, General & Internal
Emanuele Pivetta, Irene Cara, Giulia Paglietta, Virginia Scategni, Giulia Labarile, Maria Tizzani, Giulio Porrino, Stefania Locatelli, Gilberto Calzolari, Fulvio Morello, Milena Maria Maule, Enrico Lupia
Summary: This study aimed to assess the feasibility of LUS and DUS in the ED during the COVID-19 pandemic, and the results showed that DUS can be performed in this setting and is associated with the 30-day outcome.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Microbiology
Audrey Baron, Olivier Peyrony, Maud Salmona, Nadia Mahjoub, Sami Ellouze, Maud Anastassiou, Constance Delaugerre, Jean-Paul Fontaine, Sylvie Chevret, Jerome LeGoff, Linda Feghoul
Summary: The use of the ID NOW COVID-19 system in an emergency department was found to significantly reduce the length of stay for patients. The implementation of molecular point-of-care testing for SARS-CoV-2 resulted in faster results and decreased overcrowding in the emergency department. This study emphasizes the importance and benefits of COVID-19 molecular point-of-care testing in preventing overcrowding and facilitating patient care and isolation.
MICROBIOLOGY SPECTRUM
(2022)
Article
Cardiac & Cardiovascular Systems
Daniel A. Korevaar, Ilayda Aydemir, Maartje W. Minnema, Kaoutar Azijli, Ludo F. Beenen, Jarom Heijmans, Nick van Es, Mohanad al Masoudi, Lilian J. Meijboom, Saskia Middeldorp, Prabath W. Nanayakkara, Rick I. Meijer, Peter I. Bonta, Josien van Es
Summary: COVID-19 patients have an increased risk of pulmonary embolism (PE), but there is a lack of screening algorithms for PE in these patients. A study found that patients with higher D-dimer levels were more likely to have PE, with a recommendation to perform CT pulmonary angiography (CTPA) for patients with D-dimer >= 1.00 mg/L.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2021)
Article
Medical Laboratory Technology
Pablo Leiva-Salinas, Emilio Flores, Alvaro Blasco, Ruth Torreblanca, Irene Gutierrez, Maite Lopez-Garrigos, Carlos Leiva-Salinas
Summary: This study compared the diagnostic performance of D-dimer for the diagnosis of VTE in the emergency department (ED) using conventional cut-off values versus age-adjusted values. It also investigated the ordering pattern of Doppler ultrasound (US) and computerized tomographic pulmonary angiogram (CTPA) before and after reporting the age-adjusted cut-off value.
CLINICAL BIOCHEMISTRY
(2023)
Article
Public, Environmental & Occupational Health
T. K. Teoh, J. Powell, J. Kelly, C. McDonnell, R. Whelan, N. H. O'Connell, C. P. Dunne
Summary: POCT for influenza has high sensitivity and specificity, reducing incidence of hospital-acquired influenza and admission rates compared to laboratory testing. This method may be a feasible strategy for testing patients during peak influenza seasons, benefiting clinical management in emergency departments.
JOURNAL OF HOSPITAL INFECTION
(2021)
Article
Medicine, General & Internal
Reza Rasti, Johanna Brannstrom, Andreas Martensson, Ingela Zenk, Jesper Gantelius, Giulia Gaudenzi, Helle Molsted Alvesson, Tobias Alfven
Summary: In a pediatric emergency department in Sweden, healthcare providers have a double-edged view on the utility of point-of-care tests (POCTs). While they are considered to have clinical and social value, local routines for their use were seen as distracting clinicians from patient care. Requests were made for ideal POCTs and their implementation.
Article
Medical Laboratory Technology
Marta Jimenez-Barragan, Manuel Rodriguez-Oliva, Catalina Sanchez-Mora, Carmen Navarro-Bustos, Sandra Fuentes-Cantero, Salomon Martin-Perez, Jose M. Garrido-Castilla, Luisa Undabeytia-Lopez, Antonio Luque-Cid, Juan de Miguel-Melendez, Antonio Leon-Justel
Summary: The study showed that a new patient flow based on Point-of-Care Testing (POCT) can significantly reduce Emergency Department length of stay, time to disposition decision, and laboratory turnaround time. This strategy did not lead to an increase in readmission rates, indicating it as a promising approach to optimize patient flow in the Emergency Department.
CLINICA CHIMICA ACTA
(2021)
Review
Medicine, General & Internal
Christos Verras, Ioannis Ventoulis, Sofia Bezati, Dionysis Matsiras, John Parissis, Effie Polyzogopoulou
Summary: Point-of-care ultrasound (POCUS) has been effectively used in intensive care units for managing septic patients. Its use in the emergency department (ED) has been advocated due to its cost-effectiveness and non-invasive nature. This review summarizes the existing literature on the use of POCUS as a supplementary tool in the comprehensive management of septic patients in the ED setting, highlighting its efficiency in differential diagnosis, faster identification of sepsis causes, and accurate diagnosis and management in rare and complicated cases.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Infectious Diseases
Jessica Jennifer Wentworth, Anne Lindebo Holm Ovrehus, Janne Fulgsang Hansen, Peter Biesenbach, Peer Brehm Christensen
Summary: In Denmark, a risk-based, point-of-care screening strategy in an emergency department revealed that injecting drug use was the highest risk factor for HCV-Ab positivity. Despite its feasibility, this screening strategy was ineffective, highlighting the need for further testing strategies to identify remaining hepatitis C patients.
INFECTIOUS DISEASES
(2021)
