Imaging as a biomarker in drug discovery for Alzheimer’s disease: is MRI a suitable technology?

Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease

(2014) Stephen Salloway et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

(2013) Michael W. Weiner et al.   Alzheimers & Dementia

An MRI Rating Scale for Amyloid-Related Imaging Abnormalities with Edema or Effusion

(2013) F. Barkhof et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Visual-Statistical Interpretation of 18F-FDG-PET Images for Characteristic Alzheimer Patterns in a Multicenter Study: Inter-Rater Concordance and Relationship to Automated Quantitative Evaluation

(2013) T. Yamane et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Fluorine-18 Radiolabeled Heterocycles as PET Tracers for Imaging β - Amyloid Plaques in Alzheimer’s Disease

(2013) Fanxing Zeng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

[11C]PBB3—a new PET ligand that identifies tau pathology in the brains of patients with AD

(2013) Heather Wood   Nature Reviews Neurology

Imaging markers for Alzheimer disease: Which vs how

(2013) G. B. Frisoni et al.   NEUROLOGY

Impaired default network functional connectivity in autosomal dominant Alzheimer disease

(2013) J. P. Chhatwal et al.   NEUROLOGY

Robust Automated Detection of Microstructural White Matter Degeneration in Alzheimer’s Disease Using Machine Learning Classification of Multicenter DTI Data

(2013) Martin Dyrba et al.   PLoS One

Dominantly Inherited Alzheimer Network: facilitating research and clinical trials

(2013) Krista L Moulder et al.   Alzheimers Research & Therapy

Generative FDG-PET and MRI Model of Aging and Disease Progression in Alzheimer's Disease

(2013) Juergen Dukart et al.   PLoS Computational Biology

Arterial spin labeling MRI

(2012) David A. Wolk et al.   CURRENT OPINION IN NEUROLOGY

Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis

(2012) Reisa Sperling et al.   LANCET NEUROLOGY

Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

(2012) Christopher M Clark et al.   LANCET NEUROLOGY

Changes in regional cerebral blood flow and functional connectivity in the cholinergic pathway associated with cognitive performance in subjects with mild Alzheimer's disease after 12-week donepezil treatment

(2012) Wenjun Li et al.   NEUROIMAGE

Cerebral Blood Flow Measured with 3D Pseudocontinuous Arterial Spin-labeling MR Imaging in Alzheimer Disease and Mild Cognitive Impairment: A Marker for Disease Severity

(2012) Maja A. A. Binnewijzend et al.   RADIOLOGY

Harmonization of magnetic resonance-based manual hippocampal segmentation: A mandatory step for wide clinical use

(2011) Giovanni B. Frisoni et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

(2011) Guy M. McKhann et al.   Alzheimers & Dementia

Mechanism of Amyloid Removal in Patients With Alzheimer Disease Treated With Gantenerumab

(2011) Susanne Ostrowitzki   ARCHIVES OF NEUROLOGY

Effect of Memantine on Resting State Default Mode Network Activity in Alzheimerʼs Disease

(2011) Marco Lorenzi et al.   DRUGS & AGING

Unbiased comparison of sample size estimates from longitudinal structural measures in ADNI

(2011) Dominic Holland et al.   HUMAN BRAIN MAPPING

Quantitative structural MRI for early detection of Alzheimer’s disease

(2010) Linda K McEvoy et al.   Expert Review of Neurotherapeutics

The clinical use of structural MRI in Alzheimer disease

(2010) Giovanni B. Frisoni et al.   Nature Reviews Neurology

Distinct cerebral perfusion patterns in FTLD and AD

(2010) W. T. Hu et al.   NEUROLOGY

Resting-state BOLD networks versus task-associated functional MRI for distinguishing Alzheimer's disease risk groups

(2009) Adam S. Fleisher et al.   NEUROIMAGE

Distinct patterns of brain activity in young carriers of the APOE- 4 allele

(2009) N. Filippini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain structure and function related to cognitive reserve variables in normal aging, mild cognitive impairment and Alzheimer's disease

(2007) Cristina Solé-Padullés et al.   NEUROBIOLOGY OF AGING