Journal
WORLD NEUROSURGERY
Volume 78, Issue 5, Pages -Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.wneu.2011.12.013
Keywords
DBS; Posterior subthalamic area; Tremor; Vim; Zona incerta
Categories
Funding
- University Hospital of Umea
- Foundation for Clinical Neuroscience at the University Hospital of Umea
- Parkinson Appeal U.K.
- Edmond J Safra philanthropic foundation
Ask authors/readers for more resources
OBJECTIVE: To evaluate the effects of reoperation with deep brain stimulation (DBS) in the caudal zona incerta (cZi) in patients with failed DBS in the ventral intermediate (Vim) nucleus of the thalamus for essential tremor. METHODS: The results of reoperation with cZi DBS in five patients with failed Vim DBS were retrospectively analyzed. RESULTS: Two patients had early failure of Vim DBS, and three after several years of good effect. The mean deviation from the atlas Vim target point was 1.4 mm. Before the reoperation Vim DBS improved hand function and tremor in the treated hand at 25 %, whereas cZi DBS achieved an improvement of 57%. Although cZi was more efficient than Vim DBS, also in the patients with late failure of Vim DBS, they still exhibited a considerable residual tremor on cZi DBS. CONCLUSIONS: The effect on tremor was, in this small sample population, improved by implanting an electrode in the cZi. The effect was modest in those patients suffering a deterioration years after the initial operation.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available