3.9 Article

Complete genome sequence of Streptococcus agalactiae strain SA20-06, a fish pathogen associated to meningoencephalitis outbreaks

Journal

STANDARDS IN GENOMIC SCIENCES
Volume 8, Issue 2, Pages 188-197

Publisher

BMC
DOI: 10.4056/sigs.3687314

Keywords

Streptococcus agalactiae; fish pathogen; genome sequencing

Funding

  1. Ministerio da Pesca e Aquicultura
  2. Furnas Centrais Eletricas
  3. Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
  4. Fundacao de Amparo a Pesquisa do Estado de Minas Gerais (FAPEMIG)
  5. Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)
  6. Rede Paraense de Genomica e Proteomica

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Streptococcus agalactiae (Lancefield group B; GBS) is the causative agent of meningoencephalitis in fish, mastitis in cows, and neonatal sepsis in humans. Meningoencephalitis is a major health problem for tilapia farming and is responsible for high economic losses worldwide. Despite its importance, the genomic characteristics and the main molecular mechanisms involved in virulence of S. agalactiae isolated from fish are still poorly understood. Here, we present the genomic features of the 1,820,886 bp long complete genome sequence of S. agalactiae SA20-06 isolated from a meningoencephalitis outbreak in Nile tilapia (Oreochromis niloticus) from Brazil, and its annotation, consisting of 1,710 protein-coding genes (excluding pseudogenes), 7 rRNA operons, 79 tRNA genes and 62 pseudogenes.

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