Analyses of the three 1-Cys Peroxiredoxins from Aspergillus fumigatus reveal that cytosolic Prx1 is central to H2O2 metabolism and virulence

Monitoring H2O2 inside Aspergillus fumigatus with an Integrated Microelectrode: The Role of Peroxiredoxin Protein Prx1

(2018) Carla Santana Santos et al.   ANALYTICAL CHEMISTRY

Proteolytic cleavage by the inner membrane peptidase (IMP) complex or Oct1 peptidase controls the localization of the yeast peroxiredoxin Prx1 to distinct mitochondrial compartments

(2017) Fernando Gomes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin-3 impacts Cryptococcus neoformans infection through direct antifungal effects

(2017) Fausto Almeida et al.   Nature Communications

An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins

(2017) Angela F. Harper et al.   PLoS Computational Biology

PrxQ B from Mycobacterium tuberculosis is a monomeric, thioredoxin-dependent and highly efficient fatty acid hydroperoxide reductase

(2016) Aníbal M. Reyes et al.   FREE RADICAL BIOLOGY AND MEDICINE

Entamoeba thiol-based redox metabolism: A potential target for drug development

(2016) Ghulam Jeelani et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Typical 2-Cys peroxiredoxins in human parasites: Several physiological roles for a potential chemotherapy target

(2016) Francesco Angelucci et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Mitogen activated protein kinases SakAHOG1and MpkC collaborate forAspergillus fumigatusvirulence

(2016) Ariane Cristina Mendes de Oliveira Bruder Nascimento et al.   MOLECULAR MICROBIOLOGY

Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite

(2016) Thiago G. P. Alegria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Crystal Structure of Peroxiredoxin Asp f3 Provides Mechanistic Insight into Oxidative Stress Resistance and Virulence of Aspergillus fumigatus

(2016) Falk Hillmann et al.   Scientific Reports

Phenylpyrroles: 30 Years, Two Molecules and (Nearly) No Resistance

(2016) Jaafar Kilani et al.   Frontiers in Microbiology

Catalytic Thr or Ser Residue Modulates Structural Switches in 2-Cys Peroxiredoxin by Distinct Mechanisms

(2016) Carlos A. Tairum et al.   Scientific Reports

The Aspergillus fumigatus sitA Phosphatase Homologue Is Important for Adhesion, Cell Wall Integrity, Biofilm Formation, and Virulence

(2015) Vinícius Leite Pedro Bom et al.   EUKARYOTIC CELL

Mitochondrial dynamics in the pathogenic moldAspergillus fumigatus: therapeutic and evolutionary implications

(2015) Michael Neubauer et al.   MOLECULAR MICROBIOLOGY

The Aspergillus fumigatus pkcAG579R Mutant Is Defective in the Activation of the Cell Wall Integrity Pathway but Is Dispensable for Virulence in a Neutropenic Mouse Infection Model

(2015) Marina Campos Rocha et al.   PLoS One

Republished: The clinical spectrum of pulmonary aspergillosis

(2015) Chris Kosmidis et al.   POSTGRADUATE MEDICAL JOURNAL

Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling

(2015) Arden Perkins et al.   TRENDS IN BIOCHEMICAL SCIENCES

Systematic characterization of the peroxidase gene family provides new insights into fungal pathogenicity in Magnaporthe oryzae

(2015) Albely Afifa Mir et al.   Scientific Reports

Alternative oxidase: Distribution, induction, properties, structure, regulation, and functions

(2015) A. G. Rogov et al.   BIOCHEMISTRY-MOSCOW

Involvement of a 1-Cys Peroxiredoxin in Bacterial Virulence

(2014) Gilberto Hideo Kaihami et al.   PLoS Pathogens

Are Reactive Oxygen Species Always Detrimental to Pathogens?

(2013) Claudia N. Paiva et al.   ANTIOXIDANTS & REDOX SIGNALING

Sulphiredoxin plays peroxiredoxin-dependent and -independent roles via the HOG signalling pathway inCryptococcus neoformansand contributes to fungal virulence

(2013) Rajendra Upadhya et al.   MOLECULAR MICROBIOLOGY

The molecular mechanisms and physiological consequences of oxidative stress: lessons from a model bacterium

(2013) James A. Imlay   NATURE REVIEWS MICROBIOLOGY

NikA/TcsC Histidine Kinase Is Involved in Conidiation, Hyphal Morphology, and Responses to Osmotic Stress and Antifungal Chemicals in Aspergillus fumigatus

(2013) Daisuke Hagiwara et al.   PLoS One

Fungal antioxidant pathways promote survival against neutrophils during infection

(2012) Sixto M. Leal et al.   JOURNAL OF CLINICAL INVESTIGATION

Disulfide Biochemistry in 2-Cys Peroxiredoxin: Requirement of Glu50 and Arg146 for the Reduction of Yeast Tsa1 by Thioredoxin

(2012) Carlos A. Tairum et al.   JOURNAL OF MOLECULAR BIOLOGY

Aspergillus fumigatusmitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses and fungal pathogenesis

(2012) Nora Grahl et al.   MOLECULAR MICROBIOLOGY

The Stress-Activated Protein Kinase FgOS-2 Is a Key Regulator in the Life Cycle of the Cereal Pathogen Fusarium graminearum

(2012) Thuat Van Nguyen et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Characterization of a putative thioredoxin peroxidase prx1 of Candida albicans

(2012) Kavitha Srinivasa et al.   MOLECULES AND CELLS

The Two-Component Sensor Kinase TcsC and Its Role in Stress Resistance of the Human-Pathogenic Mold Aspergillus fumigatus

(2012) Allison McCormick et al.   PLoS One

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Reactive Oxygen Species in Phytopathogenic Fungi: Signaling, Development, and Disease

(2011) Jens Heller et al.   Annual Review of Phytopathology

Horseradish peroxidase compound I as a tool to investigate reactive protein-cysteine residues: from quantification to kinetics

(2011) José Carlos Toledo et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Response to Heat Shock and Oxidative Stress in Saccharomyces cerevisiae

(2011) K. A. Morano et al.   GENETICS

Automated Image Analysis of the Host-Pathogen Interaction between Phagocytes and Aspergillus fumigatus

(2011) Franziska Mech et al.   PLoS One

A Comparison of Thiol Peroxidase Mechanisms

(2010) Leopold Flohé et al.   ANTIOXIDANTS & REDOX SIGNALING

1-Cysteine peroxiredoxin: A dual-function enzyme with peroxidase and acidic Ca2+-independent phospholipase A2 activities

(2010) Timo J. Nevalainen   BIOCHIMIE

Involvement of an Alternative Oxidase in Oxidative Stress and Mycelium-to-Yeast Differentiation in Paracoccidioides brasiliensis

(2010) Vicente P. Martins et al.   EUKARYOTIC CELL

Specialized and shared functions of the histidine kinase- and HOG1 MAP kinase-mediated signaling pathways in Alternaria alternata, a filamentous fungal pathogen of citrus

(2010) Ching-Hsuan Lin et al.   FUNGAL GENETICS AND BIOLOGY

Structural and Biochemical Characterization of Peroxiredoxin Qβ fromXylella fastidiosa

(2010) Bruno Brasil Horta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional analysis of the superoxide dismutase family inAspergillus fumigatus

(2010) Karine Lambou et al.   MOLECULAR MICROBIOLOGY

A Method for Generation of Bone Marrow-Derived Macrophages from Cryopreserved Mouse Bone Marrow Cells

(2010) Fernanda M. Marim et al.   PLoS One

Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling

(2009) Andrew G. Cox et al.   BIOCHEMICAL JOURNAL

Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

(2009) F.-Nora Vögtle et al.   CELL

Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation

(2009) Erich B. Tahara et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phenotypic analysis of genes whose mRNA accumulation is dependent on calcineurin in Aspergillus fumigatus

(2009) Iran Malavazi et al.   FUNGAL GENETICS AND BIOLOGY

Silencing of mitochondrial alternative oxidase gene of Aspergillus fumigatus enhances reactive oxygen species production and killing of the fungus by macrophages

(2009) Taisa Magnani et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus

(2009) Martin Vödisch et al.   PROTEOMICS

Mitochondrial generation of free radicals and hypoxic signaling

(2009) Robert O. Poyton et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Thirty years of protein translocation into mitochondria: Unexpectedly complex and still puzzling

(2008) Dejana Mokranjac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Peroxiredoxins from Trypanosoma cruzi: Virulence factors and drug targets for treatment of Chagas disease?

(2007) María Dolores Piñeyro et al.   GENE