AIEC infection triggers modification of gut microbiota composition in genetically predisposed mice, contributing to intestinal inflammation

Bacteriophages targeting adherent invasive Escherichia coli strains as a promising new treatment for Crohn's disease

(2017) Matthieu Galtier et al.   Journal of Crohns & Colitis

The resilience of the intestinal microbiota influences health and disease

(2017) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Activation of the EIF2AK4-EIF2A/eIF2α-ATF4 pathway triggers autophagy response to Crohn disease-associated adherent-invasiveEscherichia coliinfection

(2016) Alexis Bretin et al.   Autophagy

Practical Considerations and the Intestinal Microbiome in Disease: Antibiotics for IBD Therapy

(2016) Richard N. Fedorak et al.   DIGESTIVE DISEASES

Comparative genomics of Crohn's disease-associated adherent-invasive Escherichia coli

(2016) Claire L O'Brien et al.   GUT

Fungal microbiota dysbiosis in IBD

(2016) Harry Sokol et al.   GUT

Acute dextran sulfate sodium (DSS)-induced colitis promotes gut microbial dysbiosis in mice

(2016) Peris Mumbi Munyaka et al.   JOURNAL OF BASIC MICROBIOLOGY

The amino acid sensor GCN2 controls gut inflammation by inhibiting inflammasome activation

(2016) Rajesh Ravindran et al.   NATURE

Western diet induces a shift in microbiota composition enhancing susceptibility to Adherent-Invasive E. coli infection and intestinal inflammation.

(2016) Allison Agus et al.   Scientific Reports

Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence

(2015) Monika Schaubeck et al.   GUT

Use of Germ-Free Animal Models in Microbiota-Related Research

(2015) Maha Al-Asmakh et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

TheATG16L1–T300Aallele impairs clearance of pathosymbionts in the inflamed ileal mucosa of Crohn's disease patients

(2014) Mehdi Sadaghian Sadabad et al.   GUT

The genetics of Crohn’s disease and ulcerative colitis –status quoand beyond

(2014) David Ellinghaus et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Infectious etiopathogenesis of Crohn’s disease

(2014) Jessica Carrière   WORLD JOURNAL OF GASTROENTEROLOGY

Function of the microbiota

(2013) Mirjana Rajilić-Stojanović   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Crohn's Disease–Associated Adherent Invasive Escherichia coli Modulate Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy

(2013) Hang Thi Thu Nguyen et al.   GASTROENTEROLOGY

Western diet induces dysbiosis with increasedE coliin CEABAC10 mice,alters host barrier function favouring AIEC colonisation

(2013) Margarita Martinez-Medina et al.   GUT

AIEC pathobiont instigates chronic colitis in susceptible hosts by altering microbiota composition

(2013) Benoit Chassaing et al.   GUT

Autophagy and Crohn's Disease

(2013) Hang Thi Thu Nguyen et al.   Journal of Innate Immunity

A Modular Organization of the Human Intestinal Mucosal Microbiota and Its Association with Inflammatory Bowel Disease

(2013) Maomeng Tong et al.   PLoS One

Defects in autophagy favour adherent-invasive Escherichia coli persistence within macrophages leading to increased pro-inflammatory response

(2012) Pierre Lapaquette et al.   CELLULAR MICROBIOLOGY

Antibiotic Exposure and IBD Development Among Children: A Population-Based Cohort Study

(2012) M. P. Kronman et al.   PEDIATRICS

Fecal Lipocalin 2, a Sensitive and Broadly Dynamic Non-Invasive Biomarker for Intestinal Inflammation

(2012) Benoit Chassaing et al.   PLoS One

Nod2 is essential for temporal development of intestinal microbial communities

(2011) A. Rehman et al.   GUT

Altered gut microbiota composition in immune-impairedNod2−/−mice

(2011) Stanislas Mondot et al.   GUT

Changes in Human Fecal Microbiota Due to Chemotherapy Analyzed by TaqMan-PCR, 454 Sequencing and PCR-DGGE Fingerprinting

(2011) Jutta Zwielehner et al.   PLoS One

A Pyrosequencing Study in Twins Shows That Gastrointestinal Microbial Profiles Vary With Inflammatory Bowel Disease Phenotypes

(2010) Ben P. Willing et al.   GASTROENTEROLOGY

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

(2010) J. G. Caporaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crohn's disease-associated adherent-invasiveE. coliare selectively favoured by impaired autophagy to replicate intracellularly

(2009) Pierre Lapaquette et al.   CELLULAR MICROBIOLOGY

Molecular diversity of Escherichia coli in the human gut: New ecological evidence supporting the role of adherent-invasive E. coli (AIEC) in Crohnʼs disease

(2009) Margarita Martinez-Medina et al.   INFLAMMATORY BOWEL DISEASES

Crohn's disease adherent-invasiveEscherichia colicolonize and induce strong gut inflammation in transgenic mice expressing human CEACAM

(2009) Frédéric A. Carvalho et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Metagenomic Approaches for Defining the Pathogenesis of Inflammatory Bowel Diseases

(2008) Daniel A. Peterson et al.   Cell Host & Microbe

Functional characterisation of decoy receptor 3 in Crohn's disease

(2008) B Funke et al.   GUT

Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease

(2008) Subra Kugathasan et al.   NATURE GENETICS