Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy

Inhibition of Kupffer Cell Autophagy Abrogates Nanoparticle-Induced Liver Injury

(2017) Shasha Zhu et al.   Advanced Healthcare Materials

Fibroblast growth factor 21, fibroblast growth factor receptor 1, and β-Klotho expression in bovine growth hormone transgenic and growth hormone receptor knockout mice

(2016) Nicole E. Brooks et al.   GROWTH HORMONE & IGF RESEARCH

Diabetic Nephropathy: Perspective on Novel Molecular Mechanisms

(2016) Luigi Gnudi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Prolyl hydroxylase 2 (PHD2) inhibition protects human renal epithelial cells and mice kidney from hypoxia injury

(2016) Yi Fang et al.   Oncotarget

Novel inducers of BECN1-independent autophagy:cis-unsaturated fatty acids

(2015) Mireia Niso-Santano et al.   Autophagy

Acetyl-CoA carboxylase 2 suppression rescues human proximal tubular cells from palmitic acid induced lipotoxicity via autophagy

(2015) Wei Xin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR–YY1–PGC1α pathway

(2015) Kunqian Ji et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy regulates insulin resistance following endoplasmic reticulum stress in diabetes

(2015) Ning Zhang et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

The role of fatty acids in insulin resistance

(2015) Barry Sears et al.   Lipids in Health and Disease

Decreased exposure of simvastatin and simvastatin acid in a rat model of type 2 diabetes

(2014) Dan Xu et al.   ACTA PHARMACOLOGICA SINICA

Therapeutic Effect of Alprostadil in Diabetic Nephropathy: Possible Roles of Angiopoietin-2 and IL-18

(2014) Changqing Luo et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Liraglutide inhibits autophagy and apoptosis induced by high glucose through GLP-1R in renal tubular epithelial cells

(2014) X ZHAO et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Effect of Candesartan on Microalbuminuria and Albumin Excretion Rate in Diabetes

(2013) Rudy Bilous   ANNALS OF INTERNAL MEDICINE

Autophagy protects kidney proximal tubule epithelial cells from mitochondrial metabolic stress

(2013) Tomonori Kimura et al.   Autophagy

Enhancement of Autophagy by Simvastatin through Inhibition of Rac1-mTOR Signaling Pathway in Coronary Arterial Myocytes

(2013) Yu-Miao Wei et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Fibroblast Growth Factor 21 Improves Insulin Resistance and Ameliorates Renal Injury indb/dbMice

(2013) H. W. Kim et al.   ENDOCRINOLOGY

Prostaglandin E1 Increases the Blood Flow Rate of Saphenous Vein Grafts in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting

(2013) LiYun Zhao et al.   JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA

Obesity-Mediated Autophagy Insufficiency Exacerbates Proteinuria-induced Tubulointerstitial Lesions

(2013) K. Yamahara et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Attenuation of Hyperlipidemia- and Diabetes-Induced Early-Stage Apoptosis and Late-Stage Renal Dysfunction via Administration of Fibroblast Growth Factor-21 Is Associated with Suppression of Renal Inflammation

(2013) Chi Zhang et al.   PLoS One

The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy

(2013) Kosuke Yamahara et al.   Journal of Diabetes Research

Homeostasis model assessment of insulin resistance for evaluating insulin sensitivity in patients with type 2 diabetes on insulin therapy

(2012) Kohei Okita et al.   ENDOCRINE JOURNAL

Inhibition of Autophagy Rescues Palmitic Acid-induced Necroptosis of Endothelial Cells

(2012) Muhammad Jadoon Khan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

(2012) Kook Hwan Kim et al.   NATURE MEDICINE

Long-term observation of renal function on combination therapy with prostaglandin and angiotensin-converting enzyme inhibitor for chronic kidney disease

(2011) Y. Nakayama et al.   CLINICAL NEPHROLOGY

The effects of fibroblast growth factor-21 knockdown and over-expression on its signaling pathway and glucose–lipid metabolism in vitro

(2011) Ke Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Protective Effect of Prostaglandin E1 on Renal Microvascular Injury in Rats of Acute Aristolochic Acid Nephropathy

(2011) Dong Sun et al.   RENAL FAILURE

Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice

(2010) Björn Hartleben et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Insulin resistance, microalbuminuria, and chronic kidney disease

(2008) Pantelis A. Sarafidis et al.   CURRENT HYPERTENSION REPORTS

Insulin Sensitivity Measured With Euglycemic Clamp Is Independently Associated With Glomerular Filtration Rate in a Community-Based Cohort

(2008) E. Nerpin et al.   DIABETES CARE

Protective Role of Autophagy in Palmitate-Induced INS-1 β-Cell Death

(2008) Sung-E Choi et al.   ENDOCRINOLOGY

Obesity and Free Fatty Acids

(2008) Guenther Boden   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA