Article
Geriatrics & Gerontology
Matti Hyvarinen, Juha Karvanen, Hanna-Kaarina Juppi, Jari E. Karppinen, Tuija H. Tammelin, Vuokko Kovanen, Pauliina Aukee, Sarianna Sipila, Timo Rantalainen, Eija K. Laakkonen
Summary: The objective of this study was to examine the associations between menopausal symptoms and cardiometabolic risk factors. The authors conducted a cross-sectional and longitudinal study on a representative population sample of women aged 47-55 years. The results showed modest positive associations between menopausal symptoms and cholesterol and fat mass measures, but these associations disappeared after adjusting for confounders. Menopausal symptoms did not predict changes in risk factors during the follow-up period.
Article
Clinical Neurology
Sae Young Jae, Kevin S. Heffernan, Sudhir Kurl, Setor K. Kunutsor, Jari A. Laukkanen
Summary: This study found that estimated pulse wave velocity (ePWV) is independently associated with the risk of stroke in middle-aged men, with higher ePWV values being associated with an increased risk of stroke (including ischemic and hemorrhagic stroke).
INTERNATIONAL JOURNAL OF STROKE
(2021)
Article
Cardiac & Cardiovascular Systems
Xuan Deng, Yongjian Song, Xu Han, Xueyu Chen, Wenyi Yang, Shouling Wu, Yong Zhou
Summary: This study aimed to identify multiple brachial-ankle Pulse Wave Velocity (baPWV) trajectory phenotypes and assess their determinants. Four distinct baPWV trajectories were identified, mainly determined by mean arterial pressure and age. Additionally, several biochemical markers and body mass index were associated with the trajectory.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Environmental Sciences
Liu Han Rui, Li Chen Yang, Xia Xue, Chen Shu Feng, Lu Xiang Feng, Gu Dong Feng, Liu Fang Chao, Huang Jian Feng
Summary: Through a cohort study involving middle-aged and elderly Chinese individuals, we have obtained novel evidence that an increased ePWV or progression of ePWV is independently associated with all-cause mortality, emphasizing the importance of mitigating ePWV progression in clinical practice.
BIOMEDICAL AND ENVIRONMENTAL SCIENCES
(2022)
Article
Geriatrics & Gerontology
Yuanlong Hu, Jiaming Huan, Xiaojie Wang, Lin Lin, Yuan Li, Lei Zhang, Yunlun Li
Summary: This study investigated the association between estimated pulse wave velocity (ePWV) and frailty in middle-aged and older adults with cardiometabolic disease (CMD). The findings revealed that a higher ePWV level was associated with an increased risk of frailty, and the association showed a non-linear relationship. This suggests that ePWV could serve as a viable alternative for assessing frailty.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Multidisciplinary Sciences
Eero A. Haapala, Earric Lee, Jari Karppinen, Hannamari Skog, Maarit Valtonen, Urho M. Kujala, Jari A. Laukkanen, Johanna K. Ihalainen, Eija K. Laakkonen
Summary: This study investigated the relationship between cardiorespiratory fitness, body composition, and arterial stiffness in women. The results showed that higher cardiorespiratory fitness and lower body fat percentage were associated with lower arterial stiffness, while higher mean arterial pressure was associated with higher arterial stiffness.
SCIENTIFIC REPORTS
(2022)
Article
Physiology
Matthew P. Harber, Allison McCurry, Nicholas Carlini, Brandon Kistler, Bradley S. Fleenor
Summary: The study found that in healthy middle-aged men, pre-exercise caffeine ingestion led to higher central and peripheral systolic blood pressures, PWV, and AIx at 30 minutes post-exercise, indicating an increased left ventricular workload which may have implications for cardiovascular event risk.
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Article
Medicine, General & Internal
Qi Zhai, Jing Wen, Meiping Wang, Yingting Zuo, Xin Su, Yibo Zhang, Herbert Gaisano, Yan He
Summary: The study found that isolated GHF was not associated with arterial stiffness, but when GHF coexisted with abnormal metabolism, there was an increased risk of elevated pulse pressure. The interaction between GHF and abnormal metabolism significantly enhanced arterial stiffness, emphasizing the importance of distinguishing even slight changes in renal function to prevent arterial stiffness.
FRONTIERS IN MEDICINE
(2021)
Article
Nutrition & Dietetics
Alma Cypiene, Silvija Gimzauskaite, Egidija Rinkuniene, Eugenijus Jasiunas, Rita Rugiene, Edita Kazenaite, Ligita Ryliskyte, Jolita Badariene
Summary: This study evaluated the influence of water intake on early vascular aging in metabolic middle-aged patients with hyperuricemia. It found that insufficient water intake is associated with increased arterial stiffness and has a negative effect on vascular health in metabolic women with hyperuricemia.
Article
Nutrition & Dietetics
Ria Kwon, Yoosoo Chang, Yejin Kim, Yoosun Cho, Hye Rin Choi, Ga-Young Lim, Jeonggyu Kang, Kye-Hyun Kim, Hoon Kim, Yun Soo Hong, Jihwan Park, Di Zhao, Sanjay Rampal, Juhee Cho, Eliseo Guallar, Hyun-Young Park, Seungho Ryu
Summary: The role of alcohol consumption in the risk of vasomotor symptoms among premenopausal women was examined. Greater alcohol consumption was associated with an increased risk of vasomotor symptoms. Refraining from alcohol consumption may help prevent these symptoms in premenopausal women.
Article
Health Care Sciences & Services
Byung Sik Kim, Yonggu Lee, Jin-Kyu Park, Young-Hyo Lim, Jeong-Hun Shin
Summary: This study investigated the association between ePWV and cardiovascular disease outcomes in Korean adults. The findings suggest that higher ePWV is associated with increased risk of cardiovascular mortality and adverse cardiovascular outcomes.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Geriatrics & Gerontology
Soichiro Nihei, Madoka Ogawa, Yuto Hashimoto, Naoki Kikuchi, Koichi Nakazato, Takanobu Okamoto
Summary: This study examined the relationship between cognitive decline, arterial stiffness, and reduction in physical fitness in middle-aged and older adults. The results showed that increased arterial stiffness and reduced physical fitness are associated with impaired cognitive function.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2023)
Article
Obstetrics & Gynecology
M. Kazama, M. Terauchi, T. Odai, K. Kato, N. Miyasaka
Summary: This cross-sectional study explored the relationship between body composition and physical and mental symptom severity in middle-aged women. The findings showed that higher fat mass index (FMI) was associated with more severe hot flashes, while higher lean mass index (LMI) was associated with less severe insomnia.
Article
Environmental Sciences
Genoa R. Warner, Diana C. Pacyga, Rita S. Strakovsky, Rebecca Smith, Tamarra James-Todd, Paige L. Williams, Russ Hauser, Daryl D. Meling, Zhong Li, Jodi A. Flaws
Summary: The study revealed associations between phthalates and hot flashes in midlife women, suggesting a potential impact on hot flash risk. Factors such as menopause status, BMI, race/ethnicity, and depressive symptoms may influence these associations.
ENVIRONMENTAL RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Max J. van Hout, Ilona A. Dekkers, Jos J. Westenberg, Martin J. Schalij, Ralph L. Widya, Renee de Mutsert, Frits R. Rosendaal, Albert de Roos, J. Wouter Jukema, Arthur J. Scholte, Hildo J. Lamb
Summary: This study provides normal and reference values for CMR-assessed PWV per sex, age and blood pressure category in the general population. The results show that PWV increases with advancing age and blood pressure categories, with women having higher PWV in high blood pressure situations.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2021)