Differential T Cell Signaling Pathway Activation by Tacrolimus and Belatacept after Kidney Transplantation: Post Hoc Analysis of a Randomised-Controlled Trial

A Randomized Controlled Clinical Trial Comparing Belatacept With Tacrolimus After De Novo Kidney Transplantation

(2017) Gretchen N. de Graav et al.   TRANSPLANTATION

High Intrapatient Tacrolimus Variability Is Associated With Worse Outcomes in Renal Transplantation Using a Low-Dose Tacrolimus Immunosuppressive Regime

(2017) Henry R. Whalen et al.   TRANSPLANTATION

The Effect of Tacrolimus and Mycophenolic Acid on CD14+ Monocyte Activation and Function

(2017) Nynke M. Kannegieter et al.   PLoS One

Costimulation Blockade in Kidney Transplantation

(2016) Lionel Rostaing et al.   TRANSPLANTATION

An Acute Cellular Rejection With Detrimental Outcome Occurring Under Belatacept-Based Immunosuppressive Therapy

(2016) Gretchen N. de Graav et al.   TRANSPLANTATION

Down-Regulation of Surface CD28 under Belatacept Treatment: An Escape Mechanism for Antigen-Reactive T-Cells

(2016) Gretchen N. de Graav et al.   PLoS One

Relationship between pharmacokinetics and pharmacodynamics of calcineurin inhibitors in renal transplant patients

(2015) Antje Albring et al.   CLINICAL TRANSPLANTATION

Phosphorylated S6 kinase and S6 ribosomal protein are diagnostic markers of antibody-mediated rejection in heart allografts

(2015) Fang Li et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Therapeutic Drug Monitoring of Belatacept in Kidney Transplantation

(2015) Gretchen N. de Graav et al.   THERAPEUTIC DRUG MONITORING

T cells Exhibit Reduced Signal Transducer and Activator of Transcription 5 Phosphorylation and Upregulated Coinhibitory Molecule Expression After Kidney Transplantation

(2015) Anne P. Bouvy et al.   TRANSPLANTATION

Alloreactive CD154-expressing T-cell subsets with differential sensitivity to the immunosuppressant, belatacept: potential targets of novel belatacept-based regimens

(2015) Chethan Ashokkumar et al.   Scientific Reports

Intra-patient variability in tacrolimus exposure: Causes, consequences for clinical management

(2015) Nauras Shuker et al.   Transplantation Reviews

Flow Cytometry and Solid Organ Transplantation: A Perfect Match

(2014) Orla Maguire et al.   IMMUNOLOGICAL INVESTIGATIONS

Tacrolimus Predose Concentrations Do Not Predict the Risk of Acute Rejection After Renal Transplantation: A Pooled Analysis From Three Randomized-Controlled Clinical Trials†

(2013) R. Bouamar et al.   AMERICAN JOURNAL OF TRANSPLANTATION

OPTN/SRTR 2012 Annual Data Report: Kidney

(2013) A. J. Matas et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Nuclear translocation of nuclear factor of activated T cells (NFAT) as a quantitative pharmacodynamic parameter for tacrolimus

(2013) Orla Maguire et al.   CYTOMETRY PART A

Mycophenolic acid attenuates the tumour necrosis factor-α-mediated proinflammatory response in endothelial cells by blocking the MAPK/NF-κB and ROS pathways

(2013) Wioletta Olejarz et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Lessons From Routine Dose Adjustment of Tacrolimus in Renal Transplant Patients Based on Global Exposure

(2013) Franck Saint-Marcoux et al.   THERAPEUTIC DRUG MONITORING

Phosphospecific flow cytometry for pharmacodynamic drug monitoring: Analysis of the JAK-STAT signaling pathway

(2012) Ramin Vafadari et al.   CLINICA CHIMICA ACTA

Belatacept in kidney transplantation

(2012) David Wojciechowski et al.   Current Opinion in Organ Transplantation

Inhibitory Effect of Tacrolimus on p38 Mitogen-Activated Protein Kinase Signaling in Kidney Transplant Recipients Measured by Whole-Blood Phosphospecific Flow Cytometry

(2012) Ramin Vafadari et al.   TRANSPLANTATION

Calcineurin inhibitors and NFAT-regulated gene expression

(2011) Claudia Sommerer et al.   CLINICA CHIMICA ACTA

MEKK3 Regulates IFN-  Production in T Cells through the Rac1/2-Dependent MAPK Cascades

(2011) X. Wang et al.   JOURNAL OF IMMUNOLOGY

A Phase III Study of Belatacept-based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study)

(2010) F. Vincenti et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The TCR-mediated signaling pathways that control the direction of helper T cell differentiation

(2010) Toshinori Nakayama et al.   SEMINARS IN IMMUNOLOGY

T Cell Activation

(2009) Jennifer E. Smith-Garvin et al.   Annual Review of Immunology

Evaluation of tacrolimus abbreviated area-under-the-curve monitoring in renal transplant patients who are potientially at risk for adverse events

(2009) Yuen Yi Hon et al.   CLINICAL TRANSPLANTATION

Opportunities to Optimize Tacrolimus Therapy in Solid Organ Transplantation: Report of the European Consensus Conference

(2009) Pierre Wallemacq et al.   THERAPEUTIC DRUG MONITORING

Pharmacodynamic monitoring of calcineurin inhibitor therapy: Is there a clinical benefit?

(2008) C. Sommerer et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION