Metformin prevents DMH-induced colorectal cancer in diabetic rats by reversing the warburg effect

Colorectal cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Mutation and expression analysis of the IDH1, IDH2, DNMT3A, and MYD88 genes in colorectal cancer

(2014) Wen-Liang Li et al.   GENE

Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase

(2014) Anila K. Madiraju et al.   NATURE

Diabetes Promotes DMH-Induced Colorectal Cancer by Increasing the Activity of Glycolytic Enzymes in Rats

(2014) Yanglei Jia et al.   PLoS One

Molecular mechanism of action of metformin: old or new insights?

(2013) Graham Rena et al.   DIABETOLOGIA

The antidiabetic gutsy role of metformin uncovered?

(2013) Rémy Burcelin   GUT

Isocitrate dehydrogenase 1 is downregulated during early skin tumorigenesis which can be inhibited by overexpression of manganese superoxide dismutase

(2012) Delira Robbins et al.   CANCER SCIENCE

Diabetes Mellitus and the Incidence of Colorectal Cancer: An Updated Systematic Review and Meta-Analysis

(2012) Longying Deng et al.   DIGESTIVE DISEASES AND SCIENCES

Cancer Risk Associated with Use of Metformin and Sulfonylurea in Type 2 Diabetes: A Meta-Analysis

(2012) D. Soranna et al.   ONCOLOGIST

Pyruvate kinase M2 promotes de novo serine synthesis to sustain mTORC1 activity and cell proliferation

(2012) J. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diabetes mellitus and incidence and mortality of colorectal cancer: a systematic review and meta-analysis of cohort studies

(2011) Ying Jiang et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

The expression and significance of IDH1 and p53 in osteosarcoma

(2010) Xiang Hu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Clinical Outcomes After Radical Prostatectomy in Diabetic Patients Treated With Metformin

(2010) Trushar Patel et al.   UROLOGY

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

(2009) H. A. Hirsch et al.   CANCER RESEARCH

Combination of curcumin and green tea catechins prevents dimethylhydrazine-induced colon carcinogenesis

(2009) Gang Xu et al.   FOOD AND CHEMICAL TOXICOLOGY

Sulphonylureas and cancer: a case–control study

(2008) Matteo Monami et al.   ACTA DIABETOLOGICA

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

(2008) Heather R. Christofk et al.   NATURE

Type 2 diabetes mellitus as risk factor for colorectal cancer

(2008) Jutta M. Berster et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL