De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies
Authors
Keywords
-
Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-11-28
DOI
10.1038/s41598-017-17209-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mislocated FUS is sufficient for gain-of-toxic-function amyotrophic lateral sclerosis phenotypes in mice
- (2016) Gen Shiihashi et al. BRAIN
- Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss
- (2016) Jelena Scekic‐Zahirovic et al. EMBO JOURNAL
- ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function
- (2016) Aarti Sharma et al. Nature Communications
- TDP-43 is intercellularly transmitted across axon terminals
- (2015) Marisa S. Feiler et al. JOURNAL OF CELL BIOLOGY
- Structure and Mechanism of Dimer–Monomer Transition of a Plant Poly(A)-Binding Protein upon RNA Interaction: Insights into Its Poly(A) Tail Assembly
- (2015) Mariane Noronha Domingues et al. JOURNAL OF MOLECULAR BIOLOGY
- TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD
- (2015) J. P. Ling et al. SCIENCE
- FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis
- (2015) Yoshihiro Kino et al. Acta Neuropathologica Communications
- TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord
- (2014) Johannes Brettschneider et al. ACTA NEUROPATHOLOGICA
- ALS-Linked Mutations Enlarge TDP-43-Enriched Neuronal RNA Granules in the Dendritic Arbor
- (2014) L. Liu-Yesucevitz et al. JOURNAL OF NEUROSCIENCE
- Stages of pTDP-43 pathology in amyotrophic lateral sclerosis
- (2013) Johannes Brettschneider et al. ANNALS OF NEUROLOGY
- Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis
- (2013) Tomohiko Ishihara et al. HUMAN MOLECULAR GENETICS
- Stress granules as crucibles of ALS pathogenesis
- (2013) Yun R. Li et al. JOURNAL OF CELL BIOLOGY
- Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS
- (2013) Hong Joo Kim et al. NATURE
- Converging Mechanisms in ALS and FTD: Disrupted RNA and Protein Homeostasis
- (2013) Shuo-Chien Ling et al. NEURON
- Neuronal sensitivity to TDP-43 overexpression is dependent on timing of induction
- (2012) Ashley Cannon et al. ACTA NEUROPATHOLOGICA
- Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion
- (2012) Jacqueline C. Mitchell et al. ACTA NEUROPATHOLOGICA
- Exome Sequencing Identifies FUS Mutations as a Cause of Essential Tremor
- (2012) Nancy D. Merner et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease
- (2012) Oliver D. King et al. BRAIN RESEARCH
- Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
- (2012) Masato Kato et al. CELL
- Spliceosome integrity is defective in the motor neuron diseases ALS and SMA
- (2012) Hitomi Tsuiji et al. EMBO Molecular Medicine
- Roles of Ataxin-2 in Pathological Cascades Mediated by TAR DNA-binding Protein 43 (TDP-43) and Fused in Sarcoma (FUS)
- (2012) Yoshihiro Nihei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Requirements for Stress Granule Recruitment of Fused in Sarcoma (FUS) and TAR DNA-binding Protein of 43 kDa (TDP-43)
- (2012) Eva Bentmann et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeted Depletion of TDP-43 Expression in the Spinal Cord Motor Neurons Leads to the Development of Amyotrophic Lateral Sclerosis-like Phenotypes in Mice
- (2012) Lien-Szu Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DDA3 stabilizes microtubules and suppresses neurite formation
- (2012) P.-C. Hsieh et al. JOURNAL OF CELL SCIENCE
- De novo design of synthetic prion domains
- (2012) J. A. Toombs et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA
- (2012) Tomohiro Yamazaki et al. Cell Reports
- Type VI Adenylyl Cyclase Regulates Neurite Extension by Binding to Snapin and Snap25
- (2011) C.-S. Wu et al. MOLECULAR AND CELLULAR BIOLOGY
- Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
- (2011) Magdalini Polymenidou et al. NATURE NEUROSCIENCE
- RNA targets of wild-type and mutant FET family proteins
- (2011) Jessica I Hoell et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS
- (2011) D. Ito et al. NEUROLOGY
- Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS
- (2010) Daisuke Ito et al. ANNALS OF NEUROLOGY
- ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
- (2010) Dorothee Dormann et al. EMBO JOURNAL
- Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules
- (2010) Daryl A. Bosco et al. HUMAN MOLECULAR GENETICS
- Elevated expression of TDP-43 in the forebrain of mice is sufficient to cause neurological and pathological phenotypes mimicking FTLD-U
- (2010) Kuen-Jer Tsai et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Wild-Type Human TDP-43 Expression Causes TDP-43 Phosphorylation, Mitochondrial Aggregation, Motor Deficits, and Early Mortality in Transgenic Mice
- (2010) Y.-F. Xu et al. JOURNAL OF NEUROSCIENCE
- TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
- (2010) Ian RA Mackenzie et al. LANCET NEUROLOGY
- Prion-like transmission of protein aggregates in neurodegenerative diseases
- (2010) Patrik Brundin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Novel missense and truncating mutations in FUS/TLS in familial ALS
- (2010) S. Waibel et al. NEUROLOGY
- Tar DNA Binding Protein-43 (TDP-43) Associates with Stress Granules: Analysis of Cultured Cells and Pathological Brain Tissue
- (2010) Liqun Liu-Yesucevitz et al. PLoS One
- Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
- (2010) X. Shan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
- (2010) Hans Wils et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of Alternative Isoforms and Inclusion Body of the TAR DNA-binding Protein-43
- (2009) Yoshinori Nishimoto et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stress granules: the Tao of RNA triage
- (2008) Paul Anderson et al. TRENDS IN BIOCHEMICAL SCIENCES
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now