Reduced cell size, chromosomal aberration and altered proliferation rates are characteristics and confounding factors in the STHdh cell model of Huntington disease

Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex

(2016) Tamara Maiuri et al.   HUMAN MOLECULAR GENETICS

Protective effects of 3-alkyl luteolin derivatives are mediated by Nrf2 transcriptional activity and decreased oxidative stress in Huntington's disease mouse striatal cells

(2015) Ana M. Oliveira et al.   NEUROCHEMISTRY INTERNATIONAL

Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity

(2015) Prabhat K. Singhal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutant Huntingtin Affects Cortical Progenitor Cell Division and Development of the Mouse Neocortex

(2014) M. Molina-Calavita et al.   JOURNAL OF NEUROSCIENCE

Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease

(2014) Antonella Ferrante et al.   NEUROBIOLOGY OF DISEASE

Chromosome Instability in mouse Embryonic Stem Cells

(2014) Nerea Gaztelumendi et al.   Scientific Reports

Oxidizing Effects of Exogenous Stressors in Huntington’s Disease Knock-in Striatal Cells—Protective Effect of Cystamine and Creatine

(2013) Márcio Ribeiro et al.   TOXICOLOGICAL SCIENCES

Long-term cultured mesenchymal stem cells frequently develop genomic mutations but do not undergo malignant transformation

(2013) Y Wang et al.   Cell Death & Disease

A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington’s disease in mice

(2013) Aníbal I. Acuña et al.   Nature Communications

The fractured genome of HeLa cells

(2013) David Mittelman et al.   GENOME BIOLOGY

Mammalian sex determination—insights from humans and mice

(2012) Stefanie Eggers et al.   CHROMOSOME RESEARCH

Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells

(2012) Silvia Stingele et al.   Molecular Systems Biology

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

(2011) Lise Munsie et al.   HUMAN MOLECULAR GENETICS

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis

(2011) Surya A. Reis et al.   HUMAN MOLECULAR GENETICS

Changes in BiP availability reveal hypersensitivity to acute endoplasmic reticulum stress in cells expressing mutant huntingtin

(2011) P. Lajoie et al.   JOURNAL OF CELL SCIENCE

Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease

(2010) Cristina Blázquez et al.   BRAIN

Huntingtin Is Required for Mitotic Spindle Orientation and Mammalian Neurogenesis

(2010) Juliette D. Godin et al.   NEURON

Proteomic Changes Resulting from Gene Copy Number Variations in Cancer Cells

(2010) Tamar Geiger et al.   PLoS Genetics

Mouse models of Huntington's disease and methodological considerations for therapeutic trials

(2009) Robert J. Ferrante   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Endoreplication: polyploidy with purpose

(2009) H. O. Lee et al.   GENES & DEVELOPMENT

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Calcineurin is involved in the early activation of NMDA-mediated cell death in mutant huntingtin knock-in striatal cells

(2008) Xavier Xifró et al.   JOURNAL OF NEUROCHEMISTRY