Monocyte infiltration and proliferation reestablish myeloid cell homeostasis in the mouse retina following retinal pigment epithelial cell injury

Inflammation and its role in age-related macular degeneration

(2016) Anu Kauppinen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Identity of pigmented subretinal cells in age-related macular degeneration

(2016) Eleonora M. Lad et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Retinal Microglia in Glaucoma

(2016) Jia-Wei Wang et al.   JOURNAL OF GLAUCOMA

Monocyte-Derived Macrophages Contribute to Spontaneous Long-Term Functional Recovery after Stroke in Mice

(2016) S. Wattananit et al.   JOURNAL OF NEUROSCIENCE

Requirement for Microglia for the Maintenance of Synaptic Function and Integrity in the Mature Retina

(2016) Xu Wang et al.   JOURNAL OF NEUROSCIENCE

Microglia across the lifespan: from origin to function in brain development, plasticity and cognition

(2016) Tuan Leng Tay et al.   JOURNAL OF PHYSIOLOGY-LONDON

Friend or Foe? Resident Microglia vs Bone Marrow-Derived Microglia and Their Roles in the Retinal Degeneration

(2016) Ni Jin et al.   MOLECULAR NEUROBIOLOGY

Sall1 is a transcriptional regulator defining microglia identity and function

(2016) Anne Buttgereit et al.   NATURE IMMUNOLOGY

Purinergic mechanisms in neuroinflammation: An update from molecules to behavior

(2016) Edward Beamer et al.   NEUROPHARMACOLOGY

Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus

(2016) Nicholas H. Varvel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New tools for studying microglia in the mouse and human CNS

(2016) Mariko L. Bennett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improved cell metabolism prolongs photoreceptor survival upon retinal-pigmented epithelium loss in the sodium iodate induced model of geographic atrophy

(2016) Marina Zieger et al.   Oncotarget

Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

(2016) Chiara M Eandi et al.   eLife

Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina

(2016) E. G. O’Koren et al.   Scientific Reports

RPE necroptosis in response to oxidative stress and in AMD

(2015) Jakub Hanus et al.   AGEING RESEARCH REVIEWS

Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration

(2015) L. Zhao et al.   EMBO Molecular Medicine

Abundance of infiltrating CD163+ cells in the retina of postmortem eyes with dry and neovascular age-related macular degeneration

(2015) Eleonora M. Lad et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

(2015) Julia Bruttger et al.   IMMUNITY

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

(2015) Lars G Fritsche et al.   NATURE GENETICS

Retinal microglia: Just bystander or target for therapy?

(2015) Marcus Karlstetter et al.   PROGRESS IN RETINAL AND EYE RESEARCH

CCR2 inhibition sequesters multiple subsets of leukocytes in the bone marrow

(2015) Naoki Fujimura et al.   Scientific Reports

Microglia Versus Myeloid Cell Nomenclature during Brain Inflammation

(2015) Melanie Greter et al.   Frontiers in Immunology

Sodium iodate induced retinal degeneration: new insights from an old model

(2015) DavidR Hinton et al.   Neural Regeneration Research

The plasticity of inflammatory monocyte responses to the inflamed central nervous system

(2014) Thomas Myles Ashhurst et al.   CELLULAR IMMUNOLOGY

High-resolution intravital imaging reveals that blood-derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury

(2014) Teresa A. Evans et al.   EXPERIMENTAL NEUROLOGY

Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain

(2014) Monica R.P. Elmore et al.   NEURON

The Role of Microglia in Diabetic Retinopathy

(2014) Jeffery G. Grigsby et al.   Journal of Ophthalmology

Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor

(2013) Christopher N. Parkhurst et al.   CELL

The resolution of neuroinflammation in neurodegeneration: leukocyte recruitment via the choroid plexus

(2013) Michal Schwartz et al.   EMBO JOURNAL

CCR2+monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation inCx3cr1deficient mice

(2013) Florian Sennlaub et al.   EMBO Molecular Medicine

Myeloid Cells Expressing VEGF and Arginase-1 Following Uptake of Damaged Retinal Pigment Epithelium Suggests Potential Mechanism That Drives the Onset of Choroidal Angiogenesis in Mice

(2013) Jian Liu et al.   PLoS One

A PHASE IA DOSE-ESCALATION STUDY OF THE ANTI-FACTOR D MONOCLONAL ANTIBODY FRAGMENT FCFD4514S IN PATIENTS WITH GEOGRAPHIC ATROPHY

(2013) Diana V. Do et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

Mechanism of Inflammation in Age-Related Macular Degeneration

(2012) Francesco Parmeggiani et al.   MEDIATORS OF INFLAMMATION

Animal models of age related macular degeneration

(2012) Mark E. Pennesi et al.   MOLECULAR ASPECTS OF MEDICINE

The Fractalkine Receptor but Not CCR2 Is Present on Microglia from Embryonic Development throughout Adulthood

(2011) M. Mizutani et al.   JOURNAL OF IMMUNOLOGY

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX3CR1

(2011) Holly R. Chinnery et al.   NEUROBIOLOGY OF AGING

Microglial Morphology and Dynamic Behavior Is Regulated by Ionotropic Glutamatergic and GABAergic Neurotransmission

(2011) Aurora M. Fontainhas et al.   PLoS One

Age-related alterations in the dynamic behavior of microglia

(2010) Mausam R. Damani et al.   AGING CELL

A Novel Population of Myeloid Cells Responding to Coxsackievirus Infection Assists in the Dissemination of Virus within the Neonatal CNS

(2010) J. M. Tabor-Godwin et al.   JOURNAL OF NEUROSCIENCE

Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice

(2010) Noah Saederup et al.   PLoS One

A RANDOMIZED PILOT STUDY OF SYSTEMIC IMMUNOSUPPRESSION IN THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION WITH CHOROIDAL NEOVASCULARIZATION

(2010) Robert B Nussenblatt et al.   RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Microglia in the Mouse Retina Alter the Structure and Function of Retinal Pigmented Epithelial Cells: A Potential Cellular Interaction Relevant to AMD

(2009) Wenxin Ma et al.   PLoS One

Ex Vivo Dynamic Imaging of Retinal Microglia Using Time-Lapse Confocal Microscopy

(2008) J. E. Lee et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Age-Related Macular Degeneration

(2008) Rama D. Jager et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunopathological aspects of age-related macular degeneration

(2008) Mrinali Patel et al.   Seminars in Immunopathology

Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice

(2007) Heping Xu et al.   AGING CELL