Src-mediated tyrosine phosphorylation of Protein Kinase D2 at focal adhesions regulates cell adhesion

Protein Kinase D Enzymes as Regulators of EMT and Cancer Cell Invasion

(2016) Nisha Durand et al.   Journal of Clinical Medicine

Protein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l γ

(2016) Nisha Durand et al.   Scientific Reports

Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion

(2015) Tim Eiseler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effective Targeting of Estrogen Receptor-Negative Breast Cancers with the Protein Kinase D Inhibitor CRT0066101

(2015) S. Borges et al.   MOLECULAR CANCER THERAPEUTICS

Focal adhesion kinase-dependent focal adhesion recruitment of SH2 domains directs SRC into focal adhesions to regulate cell adhesion and migration

(2015) Jui-Chung Wu et al.   Scientific Reports

Lipid binding promotes oligomerization and focal adhesion activity of vinculin

(2014) Krishna Chinthalapudi et al.   JOURNAL OF CELL BIOLOGY

Protein Kinase D as a Potential Chemotherapeutic Target for Colorectal Cancer

(2014) N. Wei et al.   MOLECULAR CANCER THERAPEUTICS

Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes

(2014) G. M. Goni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RhoA and Membrane Fluidity Mediates the Spatially Polarized Src/FAK Activation in Response to Shear Stress

(2014) Bo Liu et al.   Scientific Reports

Protein kinase D2 induces invasion of pancreatic cancer cells by regulating matrix metalloproteinases

(2013) Christoph Wille et al.   MOLECULAR BIOLOGY OF THE CELL

Functions of cofilin in cell locomotion and invasion

(2013) Jose Javier Bravo-Cordero et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

(2012) Maria N. Navarro et al.   BIOCHEMICAL JOURNAL

PKD2 and PKD3 promote prostate cancer cell invasion by modulating NF- B- and HDAC1-mediated expression and activation of uPA

(2012) Z. Zou et al.   JOURNAL OF CELL SCIENCE

Structure and function of focal adhesions

(2011) Bernhard Wehrle-Haller   CURRENT OPINION IN CELL BIOLOGY

Protein kinase D: coupling extracellular stimuli to the regulation of cell physiology

(2011) Ya Fu et al.   EMBO REPORTS

Lysophosphatidic acid induces a migratory phenotype through a crosstalk between RhoA–Rock and Src–FAK signalling in colon cancer cells

(2011) Fernanda Leve et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protein Kinase D Regulates Cofilin Activity through p21-activated Kinase 4

(2011) Samantha J. Spratley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation

(2011) Ninel Azoitei et al.   NEURO-ONCOLOGY

Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells

(2010) Sharon A. Matthews et al.   BIOCHEMICAL JOURNAL

PKD2 mediates multi-drug resistance in breast cancer cells through modulation of P-glycoprotein expression

(2010) Jiao Chen et al.   CANCER LETTERS

Loss of cell-cell contacts induces NF-κB via RhoA-mediated activation of protein kinase D1

(2009) Catherine F. Cowell et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot

(2009) Tim Eiseler et al.   NATURE CELL BIOLOGY

Loss of PIP5KIγ, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes

(2008) Yanfeng Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Environmental sensing through focal adhesions

(2008) Benjamin Geiger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY