Niche harmony search algorithm for detecting complex disease associated high-order SNP combinations

CINOEDV: a co-information based method for detecting and visualizing n-order epistatic interactions

(2016) Junliang Shang et al.   BMC BIOINFORMATICS

Homozygosity mapping identified a novel protein truncating mutation (p.Ser100Leufs*24) of the BBS9 gene in a consanguineous Pakistani family with Bardet Biedl syndrome

(2016) Muzammil Ahmad Khan et al.   BMC Medical Genetics

Genetic association and stress mediated down-regulation in trabecular meshwork implicates MPP7 as a novel candidate gene in primary open angle glaucoma

(2016) Mansi Vishal et al.   BMC Medical Genomics

Somatically mutated ABL1 is an actionable and essential NSCLC survival gene

(2016) E. Testoni et al.   EMBO Molecular Medicine

FHSA-SED: Two-Locus Model Detection for Genome-Wide Association Study with Harmony Search Algorithm

(2016) Shouheng Tuo et al.   PLoS One

Review: High-performance computing to detect epistasis in genome scale data sets

(2015) Alex Upton et al.   BRIEFINGS IN BIOINFORMATICS

INPP4B is an oncogenic regulator in human colon cancer

(2015) S T Guo et al.   ONCOGENE

Regulation of age-related macular degeneration-like pathology by complement factor H

(2015) Christopher B. Toomey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

(2015) Meng Na Chi et al.   Oncotarget

An Improved Opposition-Based Learning Particle Swarm Optimization for the Detection of SNP-SNP Interactions

(2015) Junliang Shang et al.   Biomed Research International

High-speed exhaustive 3-locus interaction epistasis analysis on FPGAs

(2015) Jan Christian Kässens et al.   Journal of Computational Science

ANKS1B Interacts with the Cerebral Cavernous Malformation Protein-1 and Controls Endothelial Permeability but Not Sprouting Angiogenesis

(2015) Stefanie E. Herberich et al.   PLoS One

PBOOST: a GPU-based tool for parallel permutation tests in genome-wide association studies

(2014) Guangyuan Yang et al.   BIOINFORMATICS

MACOED: a multi-objective ant colony optimization algorithm for SNP epistasis detection in genome-wide association studies

(2014) Peng-Jie Jing et al.   BIOINFORMATICS

Cloud computing for detecting high-order genome-wide epistatic interaction via dynamic clustering

(2014) Xuan Guo et al.   BMC BIOINFORMATICS

IGENT: efficient entropy based algorithm for genome-wide gene-gene interaction analysis

(2014) Min-Seok Kwon et al.   BMC Medical Genomics

Fast detection of high-order epistatic interactions in genome-wide association studies using information theoretic measure

(2014) Sangseob Leem et al.   COMPUTATIONAL BIOLOGY AND CHEMISTRY

Intragenic deletions affecting two alternative transcripts of the IMMP2L gene in patients with Tourette syndrome

(2014) Birgitte Bertelsen et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Cuckoo search epistasis: a new method for exploring significant genetic interactions

(2014) M Aflakparast et al.   HEREDITY

A novel class of niche hybrid Cultural Algorithms for continuous engineering optimization

(2014) Mostafa Z. Ali et al.   INFORMATION SCIENCES

Detecting epistasis in human complex traits

(2014) Wen-Hua Wei et al.   NATURE REVIEWS GENETICS

Multifactor dimensionality reduction reveals a three-locus epistatic interaction associated with susceptibility to pulmonary tuberculosis

(2013) Ryan L Collins et al.   BioData Mining

High-Order SNP Combinations Associated with Complex Diseases: Efficient Discovery, Statistical Power and Functional Interactions

(2012) Gang Fang et al.   PLoS One

Caipirini: using gene sets to rank literature

(2012) Theodoros G Soldatos et al.   BioData Mining

Mitochondrial peptidase IMMP2L mutation causes early onset of age-associated disorders and impairs adult stem cell self-renewal

(2011) Sunil K. George et al.   AGING CELL

Block-based Bayesian epistasis association mapping with application to WTCCC type 1 diabetes data

(2011) Yu Zhang et al.   Annals of Applied Statistics

Detecting epistatic effects in association studies at a genomic level based on an ensemble approach

(2011) J. Li et al.   BIOINFORMATICS

FEPI-MB: identifying SNPs-disease association using a Markov Blanket-based approach

(2011) Bing Han et al.   BMC BIOINFORMATICS

A 32 kb Critical Region Excluding Y402H in CFH Mediates Risk for Age-Related Macular Degeneration

(2011) Theru A. Sivakumaran et al.   PLoS One

BOOST: A Fast Approach to Detecting Gene-Gene Interactions in Genome-wide Case-Control Studies

(2010) Xiang Wan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Bioinformatics challenges for genome-wide association studies

(2010) J. H. Moore et al.   BIOINFORMATICS

Ensemble of niching algorithms

(2010) E.L. Yu et al.   INFORMATION SCIENCES

A General Model for Multilocus Epistatic Interactions in Case-Control Studies

(2010) Zhong Wang et al.   PLoS One

A random forest approach to the detection of epistatic interactions in case-control studies

(2009) Rui Jiang et al.   BMC BIOINFORMATICS

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Detecting gene–gene interactions that underlie human diseases

(2009) Heather J Cordell   NATURE REVIEWS GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detecting Genes and Gene–Gene Interactions for Age-Related Macular Degeneration with a Forest-based Approach

(2009) Minghui Wang et al.   Statistics in Biopharmaceutical Research

SNPHarvester: a filtering-based approach for detecting epistatic interactions in genome-wide association studies

(2008) Can Yang et al.   BIOINFORMATICS

On the Bahadur-Efficient Testing of Uniformity by Means of the Entropy

(2008) Peter Harremoes et al.   IEEE TRANSACTIONS ON INFORMATION THEORY

High-order combination effects and biological robustness

(2008) Joseph Lehár et al.   Molecular Systems Biology