The PDK1 Inhibitor Dichloroacetate Controls Cholesterol Homeostasis Through the ERK5/MEF2 Pathway

Executive Summary: Heart Disease and Stroke Statistics—2016 Update

(2016) Dariush Mozaffarian et al.   CIRCULATION

Human Leukemic Cells performing Oxidative Phosphorylation (OXPHOS) Generate an Antioxidant Response Independently of Reactive Oxygen species (ROS) Production

(2016) Abrar Ul Haq Khan et al.   EBioMedicine

The history of Autosomal Recessive Hypercholesterolemia (ARH). From clinical observations to gene identification

(2015) Renato Fellin et al.   GENE

MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels

(2015) Leigh Goedeke et al.   NATURE MEDICINE

The presence of wild type p53 in hematological cancers improves the efficacy of combinational therapy targeting metabolism

(2015) Nerea Allende-Vega et al.   Oncotarget

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

(2015) Elena Catalán et al.   OncoImmunology

Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia

(2015) Klaus G. Parhofer   Diabetes & Metabolism Journal

Chemical Metabolic Inhibitors for the Treatment of Blood-Borne Cancers

(2014) Martin Villalba et al.   Anti-Cancer Agents in Medicinal Chemistry

The Sirt1 activator SRT3025 provides atheroprotection in Apoe−/− mice by reducing hepatic Pcsk9 secretion and enhancing Ldlr expression

(2014) Melroy X. Miranda et al.   EUROPEAN HEART JOURNAL

Extracellular-signal-regulated kinase 5 modulates the antioxidant response by transcriptionally controlling Sirtuin 1 expression in leukemic cells

(2014) Nuria Lopez-Royuela et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

SUMOylation Regulates the Transcriptional Activity of JunB in T Lymphocytes

(2014) Johan Garaude et al.   JOURNAL OF IMMUNOLOGY

Synthesis and structure–activity relationship of berberine analogues in LDLR up-regulation and AMPK activation

(2012) Yan-Xiang Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The NF-κB member p65 controls glutamine metabolism through miR-23a

(2012) Moeez G. Rathore et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

From tumor cell metabolism to tumor immune escape

(2012) Martin Villalba et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

p53 is activated in response to disruption of the pre-mRNA splicing machinery

(2012) N Allende-Vega et al.   ONCOGENE

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

Oxidative Phosphorylation Induces De Novo Expression of the MHC Class I in Tumor Cells through the ERK5 Pathway

(2010) S. Charni et al.   JOURNAL OF IMMUNOLOGY

Metabolic Modulation of Glioblastoma with Dichloroacetate

(2010) E. D. Michelakis et al.   Science Translational Medicine

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Role of dichloroacetate in the treatment of genetic mitochondrial diseases☆

(2008) Peter W. Stacpoole et al.   ADVANCED DRUG DELIVERY REVIEWS

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

(2008) E D Michelakis et al.   BRITISH JOURNAL OF CANCER

Combinatorial patterns of histone acetylations and methylations in the human genome

(2008) Zhibin Wang et al.   NATURE GENETICS