Review
Oncology
Heleen Van Puyvelde, Niki Dimou, Aikaterini Katsikari, Blanca Iciar Indave Ruiz, Lode Godderis, Inge Huybrechts, Dirk De Bacquer
Summary: This study evaluates the associations between dietary intakes of methionine, choline, or betaine and breast cancer risk. The results did not show a clear association between dietary intake of methionine or betaine and breast cancer risk. Inconclusive evidence was found for a significant inverse association between choline intake and breast cancer risk.
CANCER EPIDEMIOLOGY
(2023)
Article
Nutrition & Dietetics
Catherine Properzi, Leon A. Adams, Johnny Lo, Jill L. Sherriff, Gary P. Jeffrey, Therese A. O'Sullivan
Summary: The study compares the dietary intakes of Australian patients with NAFLD to the general Australian population and explores the relationship between nutrient or food group intake and the degree of steatosis. The findings show significant differences in energy, macronutrient, and fat intake between the NAFLD cohort and the general population. However, no individual nutrients or food groups were strongly related to hepatic fat. Focusing on overall consumption and adopting a whole-diet approach may be more effective in NAFLD treatment and prevention.
Article
Nutrition & Dietetics
Yasmine Probst, Dian C. Sulistyoningrum, Merryn J. Netting, Jacqueline F. Gould, Simon Wood, Maria Makrides, Karen P. Best, Tim J. Green
Summary: The study found that choline intake during pregnancy in Australia is generally low and may need further research and improvement.
Article
Multidisciplinary Sciences
Xing Liu, Wanshui Yang, Jessica L. Petrick, Linda M. Liao, Weibing Wang, Na He, Peter T. Campbell, Zuo-Feng Zhang, Edward Gioyannucci, Katherine A. McGlynn, Xuehong Zhang
Summary: Higher intake of dietary fiber and whole grains is associated with lower risk of liver cancer and chronic liver disease mortality, with fiber from vegetables, beans, and grains showing potential protective effects.
NATURE COMMUNICATIONS
(2021)
Article
Nutrition & Dietetics
Ting-Yu Chang, Chien-Hsien Wu, Chi-Yang Chang, Fu-Jen Lee, Bei-Wen Wang, Jia-Yau Doong, Yu-Shun Lin, Chang-Sheng Kuo, Rwei-Fen S. Huang
Summary: This case-control study found that intake of choline and betaine is associated with the development of hepatic steatosis, with low intake being linked to increased odds and high intake associated with a significant reduction in risk.
Article
Nutrition & Dietetics
Heleen Van Puyvelde, Nikos Papadimitriou, Joanna Clasen, David Muller, Carine Biessy, Pietro Ferrari, Jytte Halkjaer, Kim Overvad, Anne Tjonneland, Renee T. Fortner, Verena Katzke, Matthias B. Schulze, Paolo Chiodini, Giovanna Masala, Valeria Pala, Carlotta Sacerdote, Rosario Tumino, Marije F. Bakker, Antonio Agudo, Eva Ardanaz, Maria Dolores Chirlaque Lopez, Maria-Jose Sanchez, Ulrika Ericson, Bjorn Gylling, Therese Karlsson, Jonas Manjer, Julie A. Schmidt, Genevieve Nicolas, Corinne Casagrande, Elisabete Weiderpass, Alicia K. Heath, Lode Godderis, Koen Van Herck, Dirk De Bacquer, Marc J. Gunter, Inge Huybrechts
Summary: The study did not find strong evidence for an association between methyl-group donors involved in one-carbon metabolism and breast cancer risk. However, there was a potential U-shaped trend suggested for dietary folate intake and breast cancer risk. Further research is needed to clarify this association.
Article
Nutrition & Dietetics
Nicola P. Bondonno, Frederik Dalgaard, Kevin Murray, Raymond J. Davey, Catherine P. Bondonno, Aedin Cassidy, Joshua R. Lewis, Cecilie Kyro, Gunnar Gislason, Augustin Scalbert, Anne Tjonneland, Jonathan M. Hodgson
Summary: Higher flavonoid intake was associated with lower body fat and reduced risk of diabetes. Subpopulations with higher risk, such as those with obesity, may benefit the most from increased flavonoid intake. Different flavonoid subclasses showed significant associations with lower diabetes risk.
JOURNAL OF NUTRITION
(2021)
Article
Oncology
Monireh Sadat Seyyedsalehi, Marta Rossi, Maryam Hadji, Hamideh Rashidian, Maryam Marzban, Maria Parpinel, Federica Fiori, Ahmad Naghibzadeh-Tahami, Yusuf A. Hannun, Chiara Luberto, Kazem Zendehdel, Paolo Boffetta
Summary: This study found that dietary betaine, choline, and choline-containing compounds are associated with the risk of colorectal cancer (CRC). Men who consume phosphocholine and sphingomyelin are more likely to develop CRC, while women who consume betaine have a decreased risk. Therefore, modifying the diet to increase betaine intake and managing the consumption of animal products can help reduce the risk of CRC.
Article
Nutrition & Dietetics
Nicola P. Bondonno, Kevin Murray, Aedin Cassidy, Catherine P. Bondonno, Joshua R. Lewis, Kevin D. Croft, Cecilie Kyro, Gunnar Gislason, Christian Torp-Pedersen, Augustin Scalbert, Anne Tjonneland, Jonathan M. Hodgson, Frederik Dalgaard
Summary: The study aimed to examine the association between flavonoid intake and PAD hospitalizations and found that higher total flavonoid intake was significantly associated with a lower risk of PAD as well as other peripheral vascular diseases. The association differed according to baseline smoking status, alcohol intake, BMI, and diabetes status. Ensuring adequate consumption of flavonoid-rich foods may be a key strategy to lower the risk of PAD.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Mahdieh Golzarand, Parvin Mirmiran, Fereidoun Azizi
Summary: The study aimed to assess the association between dietary choline and betaine intake and cardiovascular disease (CVD). The results showed that overall intake of choline and betaine was not associated with CVD risk, while higher intake of free choline was associated with a lower risk of CVD.
Article
Pediatrics
Alireza Jafari, Yahya Jalilpiran, Katherine Suitor, Nick Bellissimo, Leila Azadbakht
Summary: The study did not find any evidence to support the association between dietary choline and anthropometric measurements among Iranian children. Further prospective studies with a large sample size in different populations are needed to confirm these findings.
Article
Nutrition & Dietetics
David A. Horita, Sunil Hwang, Julie M. Stegall, Walter B. Friday, David R. Kirchner, Steven H. Zeisel
Summary: This study aimed to identify biomarkers reflective of choline intake using MRS and MS techniques. The results showed a clear correlation between plasma betaine concentration and dietary choline intake, while plasma phosphatidylcholine concentration did not show a significant correlation.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2021)
Article
Biochemistry & Molecular Biology
Yukino Miyachi, Kei Akiyama, Yoshiko Tsukuda, Thanutchaporn Kumrungsee, Noriyuki Yanaka
Summary: Choline deficiency during pregnancy and lactation affects male offspring by lowering liver betaine levels, while it increases elovl3 and vanin-1 mRNA levels in female offspring. These observations suggest gender-specific responses to a choline-deficient diet.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
(2021)
Article
Nutrition & Dietetics
HanByul Jang, Hyunjung Lim, Kyung-Hee Park, SangIck Park, Hye-Ja Lee
Summary: Reduced choline and increased B/C levels during lifestyle intervention were associated with improvements in LDL-cholesterol and triglycerides, low-fat and high-fiber intakes, as well as a decrease in Firmicutes abundance. These changes in circulating choline and B/C levels could predict individuals' metabolic compositions in response to lifestyle intervention.
Article
Nutrition & Dietetics
Laura Diez-Ricote, Rodrigo San-Cristobal, M. Jose Concejo, Miguel a Martinez-Gonzalez, Dolores Corella, Jordi Salas-Salvado, Albert Goday, J. Alfredo Martinez, angel M. Alonso-Gomez, Julia Waernberg, Jesus Vioque, Dora Romaguera, Jose Lopez-Miranda, Ramon Estruch, Francisco J. Tinahones, Jose Lapetra, Lluis Serra-Majem, Aurora Bueno-Cavanillas, Josep A. Tur, Vicente Martin Sanchez, Xavier Pinto, Jose J. Gaforio, Pilar Matia-Martin, Josep Vidal, Sebastian Mas Fontao, Emilio Ros, Zenaida Vazquez-Ruiz, Carolina Ortega-Azorin, Jesus F. Garcia-Gavilan, Mireia Malcampo, Diego Martinez-Urbistondo, Lucas Tojal-Sierra, Antonio Garcia Rodriguez, Nuria Gomez-Bellvert, Alice Chaplin, Antonio Garcia-Rios, Rosa M. Bernal-Lopez, Jose M. Santos-Lozano, Javier Basterra-Gortari, Jose Sorli, Michelle Murphy, Griselda Gasulla, Victor Mico, Itziar Salaverria-Lete, Estibaliz Goni Ochandorena, Nancy Babio, Xavier Herraiz, Jose M. Ordovas, Lidia Daimiel
Summary: This study found that increasing dietary intake of choline or betaine was associated with improvements in cardiometabolic parameters and slight improvements in markers of renal function.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Oncology
Zhongguo Zhou, Rongxin Zhang, Ruojing Wang, Yaojun Zhang, Li Xu, Jinbin Chen, Jie Zhang, Zhongxi Huang, Minshan Chen, Zhizhong Pan
Article
Oncology
Dongsheng Zhou, Jianzhong Liang, Li Xu, Fengying He, Zhongguo Zhou, Yaojun Zhang, Minshan Chen
Article
Acoustics
Zhongxi Huang, Wei Zheng, Yao-Jun Zhang, Li Xu, Jin-Bin Chen, Jian-Cong Chen, Min-Shan Chen, Zhongguo Zhou
ULTRASOUND IN MEDICINE AND BIOLOGY
(2017)
Article
Oncology
Jinbin Chen, Jia Huang, Minshan Chen, Keli Yang, Jiancong Chen, Juncheng Wang, Li Xu, Zhongguo Zhou, Yaojun Zhang
Article
Oncology
Yaojun Zhang, Shaoyan Xi, Jinbin Chen, Dongsheng Zhou, Hengjun Gao, Zhongguo Zhou, Li Xu, Minshan Chen
Article
Radiology, Nuclear Medicine & Medical Imaging
Min-Ke He, Ru-Hai Zou, Wei Wei, Jing-Xian Shen, Ming Zhao, Yong-Fa Zhang, Xiao-Jun Lin, Yao-Jun Zhang, Rong-Ping Guo, Ming Shi
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2018)
Article
Oncology
Jinbin Chen, Shixun Lu, Yaojun Zhang, Li Xu, Jiancong Chen, Juncheng Wang, Minshan Chen, Rongxin Zhang, Zhongguo Zhou
Article
Oncology
Yaojun Zhang, Junting Huang, Jinbin Chen, Keli Yang, Jiancong Chen, Li Xu, Zhongguo Zhou, Minshan Chen
CANCER MANAGEMENT AND RESEARCH
(2018)
Article
Virology
Zili Hu, Huilan Zeng, Jingyu Hou, Juncheng Wang, Li Xu, Yaojun Zhang, Minshan Chen, Zhongguo Zhou
Summary: This study compared the outcomes of patients with hepatitis B virus-related hepatocellular carcinoma treated with entecavir or tenofovir disoproxil fumarate after curative radiofrequency ablation. The results showed no significant difference in recurrence-free survival and overall survival between the two treatment groups. Tenofovir disoproxil fumarate therapy was associated with better liver function protection and reduction in hepatitis B virus load.
Article
Medicine, General & Internal
Deyao Zhang, Yangxun Pan, Zhenyun Yang, Huilan Zeng, Xin Wang, Jinbin Chen, Juncheng Wang, Yaojun Zhang, Zhongguo Zhou, Minshan Chen, Dandan Hu
Summary: This study investigated the risk factors for post-hepatectomy liver failure (PHLF) by predicting and constructing an index to evaluate the risk. The independent predictive factors for PHLF included BMI, ICG-R15, INR, tumor size, HIO time, and operation method.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Deyao Zhang, Huilan Zeng, Yangxun Pan, Yumo Zhao, Xin Wang, Jinbin Chen, Juncheng Wang, Yaojun Zhang, Zhongguo Zhou, Li Xu, Minshan Chen, Dandan Hu
Summary: This study investigated the prognostic significance of liver tumor markers and blood cell indexes for predicting the site of recurrence or metastasis after surgery in patients with intrahepatic cholangiocarcinoma (ICC). The results showed that CA19-9, CEA, HALP score, and NLR can be used as reliable and cost-effective indexes for predicting the specific site of recurrence or metastasis. Patients with high HALP scores and NLR have a higher risk of intrahepatic and lymph node metastasis recurrence.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Cell Biology
Xiao-Ran Long, Yao-Jun Zhang, Mei-Yin Zhang, Keng Chen, X. F. Steven Zheng, Hui-Yun Wang
Article
Oncology
A. K. Bholee, K. Peng, Z. Zhou, J. Chen, L. Xu, Y. Zhang, M. Chen
CLINICAL & TRANSLATIONAL ONCOLOGY
(2017)
Article
Oncology
Jian-Cong Chen, Rong-Xin Zhang, Min-Shan Chen, Li Xu, Jin-Bin Chen, Ke-Li Yang, Yao-Jun Zhang, Zhong-Guo Zhou
CHINESE JOURNAL OF CANCER
(2017)