Tenofovir Inhibits Wound Healing of Epithelial Cells and Fibroblasts from the Upper and Lower Human Female Reproductive Tract

High resistance barrier to tenofovir alafenamide is driven by higher loading of tenofovir diphosphate into target cells compared to tenofovir disoproxil fumarate

(2016) Nicolas A. Margot et al.   ANTIVIRAL RESEARCH

Tenofovir alafenamide (TAF) as the successor of tenofovir disoproxil fumarate (TDF)

(2016) Erik De Clercq   BIOCHEMICAL PHARMACOLOGY

Exploring Genitoanal Injury and HIV Risk Among Women

(2016) Bridgette M. Brawner et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Chemoprophylaxis With Oral Emtricitabine and Tenofovir Alafenamide Combination Protects Macaques From Rectal Simian/Human Immunodeficiency Virus Infection

(2016) Ivana Massud et al.   JOURNAL OF INFECTIOUS DISEASES

Tenofovir alafenamide for HIV: time to switch?

(2016) Shireesha Dhanireddy et al.   LANCET INFECTIOUS DISEASES

Genital Tenofovir Concentrations Correlate With Protection Against HIV Infection in the CAPRISA 004 Trial

(2015) Angela D. M. Kashuba et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Wound repair: role of immune–epithelial interactions

(2015) G Leoni et al.   Mucosal Immunology

Identification of preferential CD4+ T-cell targets for HIV infection in the cervix

(2015) V R Joag et al.   Mucosal Immunology

Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women

(2015) Jeanne M. Marrazzo et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Role of Sexual Health Professionals in Developing a Shared Concept of Risky Sexual Behavior as it Relates to HIV Transmission

(2015) Bridgette M. Brawner et al.   PUBLIC HEALTH NURSING

Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study

(2015) Karen Smith-McCune et al.   PLoS One

Effects of Tenofovir on Cytokines and Nucleotidases in HIV-1 Target Cells and the Mucosal Tissue Environment in the Female Reproductive Tract

(2014) Nabanita Biswas et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Metabolism and antiretroviral activity of tenofovir alafenamide in CD4+ T-cells and macrophages from demographically diverse donors

(2014) Rujuta A Bam et al.   ANTIVIRAL THERAPY

Phase I/II study of the pharmacokinetics, safety and antiretroviral activity of tenofovir alafenamide, a new prodrug of the HIV reverse transcriptase inhibitor tenofovir, in HIV-infected adults

(2014) M. Markowitz et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Phenotype and susceptibility to HIV infection of CD4+ Th17 cells in the human female reproductive tract

(2014) M Rodriguez-Garcia et al.   Mucosal Immunology

Sex Hormones Regulate Tenofovir-Diphosphate in Female Reproductive Tract Cells in Culture

(2014) Zheng Shen et al.   PLoS One

Vaginal Challenge with an SIV-Based Dual Reporter System Reveals That Infection Can Occur throughout the Upper and Lower Female Reproductive Tract

(2014) Daniel J. Stieh et al.   PLoS Pathogens

Antiviral Activity, Safety, and Pharmacokinetics/Pharmacodynamics of Tenofovir Alafenamide as 10-Day Monotherapy in HIV-1–Positive Adults

(2013) Peter J. Ruane et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

A multiplexed assay to detect antimicrobial peptides in biological fluids and cell secretions

(2013) Austin W. Boesch et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Effect of Tenofovir on Nucleotidases and Cytokines in HIV-1 Target Cells

(2013) Nabanita Biswas et al.   PLoS One

Unraveling the divergent results of pre-exposure prophylaxis trials for HIV prevention

(2012) Ariane van der Straten et al.   AIDS

Assessing the Relationship Between Cervical Ectopy and HIV Susceptibility: Implications for HIV Prevention in Women

(2012) Kartik K. Venkatesh et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Immunobiology of Genital Tract Trauma: Endocrine Regulation of HIV Acquisition in Women Following Sexual Assault or Genital Tract Mutilation

(2012) Mimi Ghosh et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

War and peace between WAP and HIV: role of SLPI, trappin-2, elafin and ps20 in susceptibility to HIV infection

(2012) Anna G. Drannik et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana

(2012) Michael C. Thigpen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiretroviral Prophylaxis for HIV Prevention in Heterosexual Men and Women

(2012) Jared M. Baeten et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preexposure Prophylaxis for HIV Infection among African Women

(2012) Lut Van Damme et al.   NEW ENGLAND JOURNAL OF MEDICINE

Wound Repair: Toward Understanding and Integration of Single-Cell and Multicellular Wound Responses

(2011) Kevin J. Sonnemann et al.   Annual Review of Cell and Developmental Biology

Penetration of Tenofovir and Emtricitabine in Mucosal Tissues: Implications for Prevention of HIV-1 Transmission

(2011) K. B. Patterson et al.   Science Translational Medicine

Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men

(2010) Robert M. Grant et al.   NEW ENGLAND JOURNAL OF MEDICINE

Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women

(2010) Q. Abdool Karim et al.   SCIENCE

Exposure to HIV-1 Directly Impairs Mucosal Epithelial Barrier Integrity Allowing Microbial Translocation

(2010) Aisha Nazli et al.   PLoS Pathogens

ORIGINAL ARTICLE: CCL20/MIP3α is a Novel Anti-HIV-1 Molecule of the Human Female Reproductive Tract

(2009) Mimi Ghosh et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Estradiol modulation of hepatocyte growth factor by stromal fibroblasts in the female reproductive tract

(2009) Kimberly D. Coleman et al.   FERTILITY AND STERILITY

Trappin-2/Elafin: a novel innate anti-human immunodeficiency virus-1 molecule of the human female reproductive tract

(2009) Mimi Ghosh et al.   IMMUNOLOGY

Comparison of Methods for Identifying Ano-Genital Injury After Consensual Intercourse

(2009) Therese Zink et al.   JOURNAL OF EMERGENCY MEDICINE

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE