Aβ42 pentamers/hexamers are the smallest detectable oligomers in solution

Quantifying Trace Amounts of Aggregates in Biopharmaceuticals Using Analytical Ultracentrifugation Sedimentation Velocity: Bayesian Analyses and F Statistics

(2016) Lucas Wafer et al.   AAPS Journal

Amyloid-β42 protofibrils are internalized by microglia more extensively than monomers

(2016) Lisa K. Gouwens et al.   BRAIN RESEARCH

An Account of Amyloid Oligomers: Facts and Figures Obtained from Experiments and Simulations

(2016) Luitgard Nagel-Steger et al.   CHEMBIOCHEM

Amyloid β-Protein Assembly and Alzheimer’s Disease: Dodecamers of Aβ42, but Not of Aβ40, Seed Fibril Formation

(2016) Nicholas J. Economou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Role of Amyloid-β Oligomers in Toxicity, Propagation, and Immunotherapy

(2016) Urmi Sengupta et al.   EBioMedicine

Monomeric Amyloid Beta Peptide in Hexafluoroisopropanol Detected by Small Angle Neutron Scattering

(2016) Bo Zhang-Haagen et al.   PLoS One

Amyloid β-Protein Assembly: Differential Effects of the Protective A2T Mutation and Recessive A2V Familial Alzheimer’s Disease Mutation

(2015) Xueyun Zheng et al.   ACS Chemical Neuroscience

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

(2015) Kirsten L. Viola et al.   ACTA NEUROPATHOLOGICA

The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species

(2015) Jessica M. Mc Donald et al.   Alzheimers & Dementia

Interactions between misfolded protein oligomers and membranes: A central topic in neurodegenerative diseases?

(2015) Maria Andreasen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies

(2015) Jessica Nasica-Labouze et al.   CHEMICAL REVIEWS

The structure of fibrils from ‘misfolded’ proteins

(2015) Beat H Meier et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Stabilization of Nontoxic A -Oligomers: Insights into the Mechanism of Action of Hydroxyquinolines in Alzheimer's Disease

(2015) T. M. Ryan et al.   JOURNAL OF NEUROSCIENCE

Small angle X-ray scattering analysis of Cu2+-induced oligomers of the Alzheimer's amyloid β peptide

(2015) Timothy M. Ryan et al.   Metallomics

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Aβ(1–42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease

(2015) Yiling Xiao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SDS-PAGE analysis of Aβ oligomers is disserving research into Alzheimer´s disease: appealing for ESI-IM-MS

(2015) Rosa Pujol-Pina et al.   Scientific Reports

Amyloid β Oligomeric Species Present in the Lag Phase of Amyloid Formation

(2015) Martin Wolff et al.   PLoS One

Toxic oligomer species of amyloid-β in Alzheimer's disease, a timing issue

(2015) S Lesne   SWISS MEDICAL WEEKLY

High-resolution NMR characterization of low abundance oligomers of amyloid-β without purification

(2015) Samuel A. Kotler et al.   Scientific Reports

A Hexameric Peptide Barrel as Building Block of Amyloid-β Protofibrils

(2014) Christofer Lendel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Early amyloid β-protein aggregation precedes conformational change

(2014) Bogdan Barz et al.   CHEMICAL COMMUNICATIONS

Structural evolution and membrane interactions of Alzheimer's amyloid-beta peptide oligomers: New knowledge from single-molecule fluorescence studies

(2014) Robin D. Johnson et al.   PROTEIN SCIENCE

Protein Structure Determination by Magic-Angle Spinning Solid-State NMR, and Insights into the Formation, Structure, and Stability of Amyloid Fibrils

(2013) Gemma Comellas et al.   Annual Review of Biophysics

Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ

(2013) Kanchan Garai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid β-protein oligomers and Alzheimer’s disease

(2013) Eric Y Hayden et al.   Alzheimers Research & Therapy

Laser-Induced Liquid Bead Ion Desorption Mass Spectrometry: An Approach to Precisely Monitor the Oligomerization of the β-Amyloid Peptide

(2012) Mihaela Cernescu et al.   ANALYTICAL CHEMISTRY

Aggregation analysis of pharmaceutical human immunoglobulin preparations using size-exclusion chromatography and analytical ultracentrifugation sedimentation velocity

(2012) Elena Krayukhina et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Oligomeric Intermediates in Amyloid Formation: Structure Determination and Mechanisms of Toxicity

(2012) Marcus Fändrich   JOURNAL OF MOLECULAR BIOLOGY

C-Terminal Turn Stability Determines Assembly Differences between Aβ40 and Aβ42

(2012) Robin Roychaudhuri et al.   JOURNAL OF MOLECULAR BIOLOGY

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Molecular Engineering of a Secreted, Highly Homogeneous, and Neurotoxic Aβ Dimer

(2011) Andreas Müller-Schiffmann et al.   ACS Chemical Neuroscience

Key residues for the oligomerization of Aβ42 protein in Alzheimer’s disease

(2011) Sam Ngo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Prediction of Hydrodynamic and Other Solution Properties of Rigid Proteins from Atomic- and Residue-Level Models

(2011) A. Ortega et al.   BIOPHYSICAL JOURNAL

Soluble Aβ oligomer production and toxicity

(2011) Megan E. Larson et al.   JOURNAL OF NEUROCHEMISTRY

Diffusion of the Reaction Boundary of Rapidly Interacting Macromolecules in Sedimentation Velocity

(2010) Peter Schuck   BIOPHYSICAL JOURNAL

Sedimentation Patterns of Rapidly Reversible Protein Interactions

(2010) Peter Schuck   BIOPHYSICAL JOURNAL

Amyloid  -Protein Dimers Rapidly Form Stable Synaptotoxic Protofibrils

(2010) B. O'Nuallain et al.   JOURNAL OF NEUROSCIENCE

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

Modulation of aggregate size- and shape-distributions of the amyloid-β peptide by a designed β-sheet breaker

(2009) Luitgard Nagel-Steger et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

A two-dimensional spectrum analysis for sedimentation velocity experiments of mixtures with heterogeneity in molecular weight and shape

(2009) Emre Brookes et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

The Recombinant Amyloid-β Peptide Aβ1–42 Aggregates Faster and Is More Neurotoxic than Synthetic Aβ1–42

(2009) Verena H. Finder et al.   JOURNAL OF MOLECULAR BIOLOGY

Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease

(2009) Summer L. Bernstein et al.   Nature Chemistry

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Soluble aggregates of the amyloid-β peptide are trapped by serum albumin to enhance amyloid-β activation of endothelial cells

(2009) Adriana A Reyes Barcelo et al.   Journal of Biological Engineering

A Bayesian Approach for Quantifying Trace Amounts of Antibody Aggregates by Sedimentation Velocity Analytical Ultracentrifugation

(2008) Patrick H. Brown et al.   AAPS Journal

Structure – Function Relationships of Pre-Fibrillar Protein Assemblies in Alzheimers Disease and Related Disorders

(2008) F. Rahimi et al.   Current Alzheimer Research

Amyloid β-Protein Assembly and Alzheimer Disease

(2008) Robin Roychaudhuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Quasihomogeneous nucleation of amyloid beta yields numerical bounds for the critical radius, the surface tension, and the free energy barrier for nucleus formation

(2008) K. Garai et al.   JOURNAL OF CHEMICAL PHYSICS

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE