IL-1β increases asporin expression via the NF-κB p65 pathway in nucleus pulposus cells during intervertebral disc degeneration

Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration

(2017) Daoliang Xu et al.   PHARMACOLOGICAL RESEARCH

MicroRNA-7 regulates IL-1β-induced extracellular matrix degeneration by targeting GDF5 in human nucleus pulposus cells

(2016) Wei Liu et al.   BIOMEDICINE & PHARMACOTHERAPY

Nrf2 Transcription Factor Can Directly Regulate mTOR

(2016) Gabriel Bendavit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibiting IL-1 signaling pathways to inhibit catabolic processes in disc degeneration

(2016) Jodie Daniels et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Longitudinal Comparison of Enzyme- and Laser-Treated Intervertebral Disc by MRI, X-Ray, and Histological Analyses Reveals Discrepancies in the Progression of Disc Degeneration: A Rabbit Study

(2016) Marion Fusellier et al.   Biomed Research International

Varying RGD concentration and cell phenotype alters the expression of extracellular matrix genes in vocal fold fibroblasts

(2015) Aaron M. Kosinski et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes

(2015) K.L.E. Phillips et al.   OSTEOARTHRITIS AND CARTILAGE

Effects of Nuclear Factor Kappa B Signaling Pathway in Human Intervertebral Disc Degeneration

(2015) Sun Zhongyi et al.   SPINE

Inflammatory Kinetics and Efficacy of Anti-inflammatory Treatments on Human Nucleus Pulposus Cells

(2015) Benjamin A. Walter et al.   SPINE

Hypoxia-inducible Factor (HIF)-1α and CCN2 Form a Regulatory Circuit in Hypoxic Nucleus Pulposus Cells

(2013) Cassie M. Tran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of cytokines in intervertebral disc degeneration: pain and disc content

(2013) Makarand V. Risbud et al.   Nature Reviews Rheumatology

Genetic polymorphisms associated with intervertebral disc degeneration

(2013) Jillian E. Mayer et al.   Spine Journal

Prevalence and Pattern of Lumbar Magnetic Resonance Imaging Changes in a Population Study of One Thousand Forty-Three Individuals

(2009) Kenneth M. C. Cheung et al.   SPINE

Asporin, a susceptibility gene in osteoarthritis, is expressed at higher levels in the more degenerate human intervertebral disc

(2009) Helen E Gruber et al.   ARTHRITIS RESEARCH & THERAPY

Association of the Asporin D14 Allele with Lumbar-Disc Degeneration in Asians

(2008) You-Qiang Song et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Akt-dependent regulation of NF- B is controlled by mTOR and Raptor in association with IKK

(2008) H. C. Dan et al.   GENES & DEVELOPMENT

Exuberant expression of chemokine genes by adult human articular chondrocytes in response to IL-1β

(2008) L.J. Sandell et al.   OSTEOARTHRITIS AND CARTILAGE

Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral disc

(2008) J. A. Hoyland et al.   RHEUMATOLOGY