Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients

Advanced chronic kidney disease populations have elevated trimethylamine N-oxide levels associated with increased cardiovascular events

(2016) Richard B. Kim et al.   KIDNEY INTERNATIONAL

Population-level analysis of gut microbiome variation

(2016) Gwen Falony et al.   SCIENCE

Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health

(2016) David Ríos-Covián et al.   Frontiers in Microbiology

Intestinal Microbiota‐Generated Metabolite Trimethylamine‐N‐Oxide and 5‐Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in a COURAGE‐Like Patient Cohort

(2016) Vichai Senthong et al.   Journal of the American Heart Association

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(2016)   IMMUNOLOGICAL REVIEWS

Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease

(2016) Catharina Missailidis et al.   PLoS One

The gastrointestinal microbiota and colorectal cancer

(2015) Temitope O. Keku et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Intestinal Microbiota-Dependent Phosphatidylcholine Metabolites, Diastolic Dysfunction, and Adverse Clinical Outcomes in Chronic Systolic Heart Failure

(2015) W.H. Wilson Tang et al.   JOURNAL OF CARDIAC FAILURE

The Influence of CKD on Colonic Microbial Metabolism

(2015) R. Poesen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Serum Trimethylamine-N-Oxide is Elevated in CKD and Correlates with Coronary Atherosclerosis Burden

(2015) J. R. Stubbs et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Proteobacteria: microbial signature of dysbiosis in gut microbiota

(2015) Na-Ri Shin et al.   TRENDS IN BIOTECHNOLOGY

Dysbiosis of Gut Microbiota With Reduced Trimethylamine‐N‐Oxide Level in Patients With Large‐Artery Atherosclerotic Stroke or Transient Ischemic Attack

(2015) Jia Yin et al.   Journal of the American Heart Association

Expansion of Urease- and Uricase-Containing, Indole- and p-Cresol-Forming and Contraction of Short-Chain Fatty Acid-Producing Intestinal Microbiota in ESRD

(2014) Jakk Wong et al.   AMERICAN JOURNAL OF NEPHROLOGY

Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry

(2014) Zeneng Wang et al.   ANALYTICAL BIOCHEMISTRY

Conducting a Microbiome Study

(2014) Julia K. Goodrich et al.   CELL

Transmission of Atherosclerosis Susceptibility with Gut Microbial Transplantation

(2014) Jill C. Gregory et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota

(2014) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heart Failure in Patients with Chronic Kidney Disease: A Systematic Integrative Review

(2014) Liviu Segall et al.   Biomed Research International

Trimethylamine-N-Oxide, a Metabolite Associated with Atherosclerosis, Exhibits Complex Genetic and Dietary Regulation

(2013) Brian J. Bennett et al.   Cell Metabolism

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Comparison of direct boiling method with commercial kits for extracting fecal microbiome DNA by Illumina sequencing of 16S rRNA tags

(2013) Xin Peng et al.   JOURNAL OF MICROBIOLOGICAL METHODS

A Combined Epidemiologic and Metabolomic Approach Improves CKD Prediction

(2013) E. P. Rhee et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention

(2013) Ron T Gansevoort et al.   LANCET

Evolving importance of kidney disease: from subspecialty to global health burden

(2013) Kai-Uwe Eckardt et al.   LANCET

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gut Microbiota from Twins Discordant for Obesity Modulate Metabolism in Mice

(2013) V. K. Ridaura et al.   SCIENCE

Chronic kidney disease alters intestinal microbial flora

(2012) Nosratola D. Vaziri et al.   KIDNEY INTERNATIONAL

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Exploring Bacterial Diversity in Hospital Environments by GS-FLX Titanium Pyrosequencing

(2012) Margarita Poza et al.   PLoS One

The Biological Observation Matrix (BIOM) format or: how I learned to stop worrying and love the ome-ome

(2012) Daniel McDonald et al.   GigaScience

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Pilot study of probiotic dietary supplementation for promoting healthy kidney function in patients with chronic kidney disease

(2010) Natarajan Ranganathan et al.   ADVANCES IN THERAPY

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Beneficial effects of lactic acid bacteria on human beings

(2010) Muhammad Irfan Masood et al.   CRITICAL REVIEWS IN MICROBIOLOGY

UniFrac: an effective distance metric for microbial community comparison

(2010) Catherine Lozupone et al.   ISME Journal

BIPES, a cost-effective high-throughput method for assessing microbial diversity

(2010) Hong-Wei Zhou et al.   ISME Journal

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

The role of the gut microbiota in nonalcoholic fatty liver disease

(2010) Ahmed Abu-Shanab et al.   Nature Reviews Gastroenterology & Hepatology

A Randomized, Controlled Trial of Early versus Late Initiation of Dialysis

(2010) Bruce A. Cooper et al.   NEW ENGLAND JOURNAL OF MEDICINE

PyNAST: a flexible tool for aligning sequences to a template alignment

(2009) J. G. Caporaso et al.   BIOINFORMATICS

Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers

(2009) Luying Peng et al.   JOURNAL OF NUTRITION

FastTree: Computing Large Minimum Evolution Trees with Profiles instead of a Distance Matrix

(2009) M. N. Price et al.   MOLECULAR BIOLOGY AND EVOLUTION