Modular Analysis of Peripheral Blood Gene Expression in Rheumatoid Arthritis Captures Reproducible Gene Expression Changes in Tumor Necrosis Factor Responders

Individualized Medicine from Prewomb to Tomb

(2014) Eric J. Topol   CELL

Clinical disease activity and acute phase reactant levels are discordant among patients with active rheumatoid arthritis: acute phase reactant levels contribute separately to predicting outcome at one year

(2014) Jonathan Kay et al.   ARTHRITIS RESEARCH & THERAPY

A7: Initial Assessment of Multi-biomarker Disease Activity Assay in JIA

(2014) Sarah Ringold et al.   Arthritis & Rheumatology

The potential use of expression profiling: implications for predicting treatment response in rheumatoid arthritis

(2013) Samantha Louise Smith et al.   ANNALS OF THE RHEUMATIC DISEASES

Development of a Multi-Biomarker Disease Activity Test for Rheumatoid Arthritis

(2013) Michael Centola et al.   PLoS One

Peripheral blood derived gene panels predict response to infliximab in rheumatoid arthritis and Crohn's disease

(2013) Bertalan Mesko et al.   Genome Medicine

Intravenous golimumab is effective in patients with active rheumatoid arthritis despite methotrexate therapy with responses as early as week 2: results of the phase 3, randomised, multicentre, double-blind, placebo-controlled GO-FURTHER trial

(2012) Michael E Weinblatt et al.   ANNALS OF THE RHEUMATIC DISEASES

Differential Gene Expression Profiles May Differentiate Responder and Nonresponder Patients with Rheumatoid Arthritis for Methotrexate (MTX) Monotherapy and MTX plus Tumor Necrosis Factor Inhibitor Combined Therapy

(2012) RENÊ DONIZETI RIBEIRO OLIVEIRA et al.   JOURNAL OF RHEUMATOLOGY

Validation Study of Existing Gene Expression Signatures for Anti-TNF Treatment in Patients with Rheumatoid Arthritis

(2012) Erik J. M. Toonen et al.   PLoS One

Validation of a novel multibiomarker test to assess rheumatoid arthritis disease activity

(2012) Jeffrey R. Curtis et al.   ARTHRITIS CARE & RESEARCH

Molecular discrimination of responders and nonresponders to anti-TNFalpha therapy in rheumatoid arthritis by etanercept

(2012) Dirk Koczan et al.   ARTHRITIS RESEARCH & THERAPY

Gene expression profiling in peripheral blood cells of patients with rheumatoid arthritis in response to anti-TNF-α treatments

(2011) E. Meugnier et al.   PHYSIOLOGICAL GENOMICS

Treating rheumatoid arthritis to target: recommendations of an international task force

(2010) J. S. Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

Pharmacogenomics of infliximab treatment using peripheral blood cells of patients with rheumatoid arthritis

(2010) L G M van Baarsen et al.   GENES AND IMMUNITY

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

Convergent random forest predictor: Methodology for predicting drug response from genome-scale data applied to anti-TNF response

(2009) Jadwiga R. Bienkowska et al.   GENOMICS

An Eight-Gene Blood Expression Profile Predicts the Response to Infliximab in Rheumatoid Arthritis

(2009) Antonio Julià et al.   PLoS One

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY