Rheb1 deletion in myeloid cells aggravates OVA-induced allergic inflammation in mice

Th2 cytokines impair innate immune responses to rhinovirus in respiratory epithelial cells

(2015) M. Contoli et al.   ALLERGY

Nuclear Receptor Nur77 Attenuates Airway Inflammation in Mice by Suppressing NF-κB Activity in Lung Epithelial Cells

(2015) Kondababu Kurakula et al.   JOURNAL OF IMMUNOLOGY

Recent progress in the study of the Rheb family GTPases

(2014) Jeffrey J. Heard et al.   CELLULAR SIGNALLING

Macrophage Polarization in Inflammatory Diseases

(2014) Yan-Cun Liu et al.   International Journal of Biological Sciences

Macrophages as APC and the Dendritic Cell Myth

(2014) D. A. Hume   JOURNAL OF IMMUNOLOGY

TSC1 controls macrophage polarization to prevent inflammatory disease

(2014) Linnan Zhu et al.   Nature Communications

Myeloid Colony-Stimulating Factors as Regulators of Macrophage Polarization

(2014) Thomas A. Hamilton et al.   Frontiers in Immunology

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

(2013) F. O. Martinez et al.   BLOOD

The role of macrophages in obstructive airways disease: Chronic obstructive pulmonary disease and asthma

(2013) Konstantinos Pappas et al.   CYTOKINE

Cardiac Ablation of Rheb1 Induces Impaired Heart Growth, Endoplasmic Reticulum-Associated Apoptosis and Heart Failure in Infant Mice

(2013) Yunshan Cao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Rheb and mammalian target of rapamycin in mitochondrial homoeostasis

(2013) M. J. Groenewoud et al.   Open Biology

Macrophage-Induced Tumor Angiogenesis Is Regulated by the TSC2-mTOR Pathway

(2012) W. Chen et al.   CANCER RESEARCH

The Role of Tuberous Sclerosis Complex 1 in Regulating Innate Immunity

(2012) H. Pan et al.   JOURNAL OF IMMUNOLOGY

Emerging roles of pulmonary macrophages in driving the development of severe asthma

(2012) M. Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Paradoxical Effects of Rapamycin on Experimental House Dust Mite-Induced Asthma

(2012) Karin Fredriksson et al.   PLoS One

Macrophages in Allergic Asthma: Fine-Tuning Their Pro- and Anti-Inflammatory Actions for Disease Resolution

(2011) Ana Paula Moreira et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Obstacles and opportunities for understanding macrophage polarization

(2011) P. J. Murray et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Rheb Is Essential for Murine Development

(2011) S. M. I. Goorden et al.   MOLECULAR AND CELLULAR BIOLOGY

The Mammalian Target of Rapamycin: Linking T Cell Differentiation, Function, and Metabolism

(2010) Jonathan D. Powell et al.   IMMUNITY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Macrophages

(2009) Barbro N. Melgert et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The tuberous sclerosis complex

(2009) Ksenia A. Orlova et al.   Annals of the New York Academy of Sciences

Activation of mTORC1 in two steps: Rheb-GTP activation of catalytic function and increased binding of substrates to raptor1

(2009) Joseph Avruch et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

The TSC1–TSC2 complex: a molecular switchboard controlling cell growth

(2008) Jingxiang Huang et al.   BIOCHEMICAL JOURNAL

The “Classical” Ovalbumin Challenge Model of Asthma in Mice

(2008) Rakesh Kumar et al.   CURRENT DRUG TARGETS

From phagocyte diversity and activation to probiotics: Back to Metchnikoff

(2008) Alberto Mantovani   EUROPEAN JOURNAL OF IMMUNOLOGY

The effects of oxidative stress induced by prolonged low-dose diesel exhaust particle exposure on the generation of allergic airway inflammation differ between BALB/c and C57BL/6 mice

(2008) Ying-Ji Li et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Quercetin regulates Th1/Th2 balance in a murine model of asthma

(2008) Hee-ju Park et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages

(2008) Elena Goleva et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

(2008) Edy Y Kim et al.   NATURE MEDICINE

Phospholipase D1 is an effector of Rheb in the mTOR pathway

(2008) Y. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA