miR-203 enhances let-7 biogenesis by targeting LIN28B to suppress tumor growth in lung cancer

SIRT6 Suppresses Pancreatic Cancer through Control of Lin28b

(2016) Sita Kugel et al.   CELL

Combinatorial Action of MicroRNAslet-7and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation

(2015) Carlos Stahlhut et al.   CELL CYCLE

Aberrant regulation of the LIN28A/LIN28B and let-7 loop in human malignant tumors and its effects on the hallmarks of cancer

(2015) Tianzhen Wang et al.   Molecular Cancer

IL-1β-Mediated Repression of microRNA-101 Is Crucial for Inflammation-Promoted Lung Tumorigenesis

(2014) Lin Wang et al.   CANCER RESEARCH

Expression of LIN28 and its regulatory microRNAs in adult adrenocortical cancer

(2014) André M. Faria et al.   CLINICAL ENDOCRINOLOGY

MUC1-C Induces the LIN28B→LET-7→HMGA2 Axis to Regulate Self-Renewal in NSCLC

(2014) Maroof Alam et al.   MOLECULAR CANCER RESEARCH

The Lin28/Let-7 System in Early Human Embryonic Tissue and Ectopic Pregnancy

(2014) Teresa Lozoya et al.   PLoS One

miR-203 Suppresses the Proliferation and Migration and Promotes the Apoptosis of Lung Cancer Cells by Targeting SRC

(2014) Nan Wang et al.   PLoS One

Lin28: Primal Regulator of Growth and Metabolism in Stem Cells

(2013) Ng Shyh-Chang et al.   Cell Stem Cell

Changes in Hypothalamic Expression of theLin28/let-7System and Related MicroRNAs During Postnatal Maturation and After Experimental Manipulations of Puberty

(2013) S. Sangiao-Alvarellos et al.   ENDOCRINOLOGY

Mechanisms of Lin28-Mediated miRNA and mRNA Regulation—A Structural and Functional Perspective

(2013) Florian Mayr et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28–let-7 pathway

(2013) Hao-Ming Chang et al.   NATURE

Stat3-coordinated Lin-28–let-7–HMGA2 and miR-200–ZEB1 circuits initiate and maintain oncostatin M-driven epithelial–mesenchymal transition

(2013) L Guo et al.   ONCOGENE

miR-203 Inhibits Cell Proliferation and Migration of Lung Cancer Cells by Targeting PKCα

(2013) Chen Wang et al.   PLoS One

Conserved microRNA pathway regulates developmental timing of retinal neurogenesis

(2013) A. La Torre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blockade of miR-150 Maturation by MLL-Fusion/MYC/LIN-28 Is Required for MLL-Associated Leukemia

(2012) Xi Jiang et al.   CANCER CELL

MicroRNA-203 leads to G1 phase cell cycle arrest in laryngeal carcinoma cells by directly targeting survivin

(2012) Ka Bian et al.   FEBS LETTERS

Lin28b Reprograms Adult Bone Marrow Hematopoietic Progenitors to Mediate Fetal-Like Lymphopoiesis

(2012) Joan Yuan et al.   SCIENCE

How does Lin28 let-7 control development and disease?

(2012) James E. Thornton et al.   TRENDS IN CELL BIOLOGY

Molecular Basis for Interaction of let-7 MicroRNAs with Lin28

(2011) Yunsun Nam et al.   CELL

Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms

(2011) Elena Piskounova et al.   CELL

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines

(2011) Giuditta Viticchiè et al.   CELL CYCLE

MiR-181 mediates cell differentiation by interrupting the Lin28 and let-7 feedback circuit

(2011) X Li et al.   CELL DEATH AND DIFFERENTIATION

Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer

(2011) Jieun Yun et al.   EMBO JOURNAL

Lin-28 reactivation is required for let-7 repression and proliferation in human small cell lung cancer cells

(2011) Lin Pan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28

(2011) Fionna E Loughlin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lin28: A MicroRNA Regulator with a Macro Role

(2010) Srinivas R. Viswanathan et al.   CELL

Regulatory Role of mir-203 in Prostate Cancer Progression and Metastasis

(2010) Sharanjot Saini et al.   CLINICAL CANCER RESEARCH

Identification of MicroRNAs Regulating Reprogramming FactorLIN28in Embryonic Stem Cells and Cancer Cells

(2010) Xiaomin Zhong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation

(2009) Dimitrios Iliopoulos et al.   CELL

TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation

(2009) Inha Heo et al.   CELL

Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

(2009) Surabhi Dangi-Garimella et al.   EMBO JOURNAL

Lin-28: An early embryonic sentinel that blocks Let-7 biogenesis

(2009) Martin A. Newman et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells

(2009) John P Hagan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HMGA2, MicroRNAs, and Stem Cell Aging

(2008) Scott M. Hammond et al.   CELL

Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'

(2008) T. E. Mullen et al.   GENES & DEVELOPMENT

MicroRNAs miR-186 and miR-150 Down-regulate Expression of the Pro-apoptotic Purinergic P2X7Receptor by Activation of Instability Sites at the 3′-Untranslated Region of the Gene That Decrease Steady-state Levels of the Transcript

(2008) Lingyin Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determinants of MicroRNA Processing Inhibition by the Developmentally Regulated RNA-binding Protein Lin28

(2008) Elena Piskounova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

Suppression of non-small cell lung tumor development by the let-7 microRNA family

(2008) M. S. Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

(2008) M. A. Newman et al.   RNA

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE