Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications

Genetic basis of rheumatoid arthritis: A current review

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Autoimmune priming, tissue attack and chronic inflammation - The three stages of rheumatoid arthritis

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TNF inhibitors – Mechanisms of action, approved and off-label indications

(2014) Grzegorz Cessak et al.   Pharmacological Reports

Interleukin 6 and Rheumatoid Arthritis

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Inflammatory Cytokines Associated with Degenerative Disc Disease Control Aggrecanase-1 (ADAMTS-4) Expression in Nucleus Pulposus Cells through MAPK and NF-κB

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Association of Granulomatosis With Polyangiitis (Wegener's) WithHLA-DPB1*04andSEMA6AGene Variants: Evidence From Genome-Wide Analysis

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Identification of a calmodulin-binding domain in Sema4D that regulates its exodomain shedding in platelets

(2013) P. Mou et al.   BLOOD

The role of semaphorins and their receptors in vascular development and cancer

(2013) Chenghua Gu et al.   EXPERIMENTAL CELL RESEARCH

Sema3A regulates bone-mass accrual through sensory innervations

(2013) Toru Fukuda et al.   NATURE

Sema 4D/CD100-plexin B is a multifunctional counter-receptor

(2012) Yusi Zhang et al.   Cellular & Molecular Immunology

Elevation of Sema4A Implicates Th Cell Skewing and the Efficacy of IFN-  Therapy in Multiple Sclerosis

(2012) Y. Nakatsuji et al.   JOURNAL OF IMMUNOLOGY

Osteoprotection by semaphorin 3A

(2012) Mikihito Hayashi et al.   NATURE

Semaphorins in cancer: Biological mechanisms and therapeutic approaches

(2012) Michael Rehman et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Diverse roles for semaphorin−plexin signaling in the immune system

(2012) Hyota Takamatsu et al.   TRENDS IN IMMUNOLOGY

Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus

(2012) Zahava Vadasz et al.   ARTHRITIS RESEARCH & THERAPY

Suppression of bone formation by osteoclastic expression of semaphorin 4D

(2011) Takako Negishi-Koga et al.   NATURE MEDICINE

Regulation of bone by the adaptive immune system in arthritis

(2011) Kazuo Okamoto et al.   ARTHRITIS RESEARCH & THERAPY

Neuropilins and semaphorins — from angiogenesis to autoimmunity

(2010) Z. Vadasz et al.   AUTOIMMUNITY REVIEWS

Blood vessels, a potential therapeutic target in rheumatoid arthritis?

(2010) Luca Semerano et al.   JOINT BONE SPINE

The Neuroimmune Semaphorin-3A Reduces Inflammation and Progression of Experimental Autoimmune Arthritis

(2010) A. Catalano   JOURNAL OF IMMUNOLOGY

The role of ADAMTSs in arthritis

(2010) Edward A. Lin et al.   Protein & Cell

Unmasking of a protective tumor necrosis factor receptor I-mediated signal in the collagen-induced arthritis model

(2009) Cheryll Williams-Skipp et al.   ARTHRITIS AND RHEUMATISM

Roles of Sema4D-Plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis

(2009) T. Okuno et al.   JOURNAL OF IMMUNOLOGY

Roles of semaphorins in the immune and hematopoietic system

(2009) Jong Dae Ji et al.   RHEUMATOLOGY INTERNATIONAL

Interleukin-17 Promotes Autoimmunity by Triggering a Positive-Feedback Loop via Interleukin-6 Induction

(2008) Hideki Ogura et al.   IMMUNITY

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages

(2008) Jose Rafael Sierra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The ADAM metalloproteinases

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Semaphorin signaling: progress made and promises ahead

(2008) Yeping Zhou et al.   TRENDS IN BIOCHEMICAL SCIENCES