Journal
SCIENTIFIC REPORTS
Volume 7, Issue -, Pages -Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/srep44798
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Funding
- National Science Foundation of China [61665012, 61575168]
- Natural Science Foundation of Xinjiang [201412112]
- Xinjiang University doctoral innovation project [XJUBSCX-2012016]
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Hydatid, which is a parasitic disease, occurs today in many regions worldwide. Because it can present a serious threat to people's health, finding a fast, convenient, and economical means of detection is important. This paper proposes a label-and spectrophotometer-free apparatus that uses optical biological detection based on porous silicon microcavities. In this approach, the refractive index change induced by the biological reactions of a sample in a porous silicon microcavity is detected by measuring the change in the incidence angle corresponding to the maximum transmitted intensity of a nearinfrared probe laser. This paper reports that the proposed method can achieve the label-free detection of 43 kDa molecular weight hydatid disease antigens with high sensitivity.
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