Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts

Protein kinase A catalytic subunit isoform PRKACA; History, function and physiology

(2016) Rigney E. Turnham et al.   GENE

Hsa-miR-1246 and hsa-miR-1290 are associated with stemness and invasiveness of non-small cell lung cancer

(2016) Gwangil Kim et al.   LUNG CANCER

Analysis of an independent tumor suppressor locus telomeric to Tp53 suggested Inpp5k and Myo1c as novel tumor suppressor gene candidates in this region

(2015) Carola Hedberg Oldfors et al.   BMC GENETICS

Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis

(2015) Amal M. El-Naggar et al.   CANCER CELL

Cancer cell metabolism and developmental homeodomain/POU domain transcription factors: A connecting link

(2015) Biswa Pratim Das Purkayastha et al.   CANCER LETTERS

Tumour exosome integrins determine organotropic metastasis

(2015) Ayuko Hoshino et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Host Matrix Modulation by Tumor Exosomes Promotes Motility and Invasiveness

(2015) Wei Mu et al.   NEOPLASIA

MiR-1246 promotes SiHa cervical cancer cell proliferation, invasion, and migration through suppression of its target gene thrombospondin 2

(2014) Junying Chen et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

CSF1/CSF1R Blockade Reprograms Tumor-Infiltrating Macrophages and Improves Response to T-cell Checkpoint Immunotherapy in Pancreatic Cancer Models

(2014) Y. Zhu et al.   CANCER RESEARCH

The high mobility group A1 molecular switch: turning on cancer – can we turn it off?

(2014) Tait H Huso et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

miR-638 Regulates Differentiation and Proliferation in Leukemic Cells by Targeting Cyclin-dependent Kinase 2

(2014) Yi Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High calcium concentration in bones promotes bone metastasis in renal cell carcinomas expressing calcium-sensing receptor

(2014) Elke Joeckel et al.   Molecular Cancer

Circulating Exosomal microRNAs as Biomarkers of Colon Cancer

(2014) Hiroko Ogata-Kawata et al.   PLoS One

Next-Generation Sequencing Analysis of MiRNA Expression in Control and FSHD Myogenesis

(2014) Veronica Colangelo et al.   PLoS One

Disruption of CXCR2-Mediated MDSC Tumor Trafficking Enhances Anti-PD1 Efficacy

(2014) S. L. Highfill et al.   Science Translational Medicine

Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies

(2014) S. Hettmer et al.   Cold Spring Harbor Perspectives in Medicine

Classification of Rhabdomyosarcoma and Its Molecular Basis

(2013) David M. Parham et al.   ADVANCES IN ANATOMIC PATHOLOGY

First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications

(2013) Isabella V. Miller et al.   BIOLOGY OF THE CELL

Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for oesophageal squamous cell carcinoma

(2013) N Takeshita et al.   BRITISH JOURNAL OF CANCER

Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review

(2013) Asfar S. Azmi et al.   CANCER AND METASTASIS REVIEWS

Myotube-derived exosomal miRNAs downregulate Sirtuin1 in myoblasts during muscle cell differentiation

(2013) Alexis Forterre et al.   CELL CYCLE

Dual Blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) Pathways Synergistically Inhibits Rhabdomyosarcoma Cell Growth In Vitro and In Vivo

(2013) J. Renshaw et al.   CLINICAL CANCER RESEARCH

What is new in the biology and treatment of pediatric rhabdomyosarcoma?

(2013) Douglas S. Hawkins et al.   CURRENT OPINION IN PEDIATRICS

Simultaneous targeting of insulin-like growth factor-1 receptor and anaplastic lymphoma kinase in embryonal and alveolar rhabdomyosarcoma: A rational choice

(2013) J. Carlijn van Gaal et al.   EUROPEAN JOURNAL OF CANCER

MicroRNA and Protein Profiling of Brain Metastasis Competent Cell-Derived Exosomes

(2013) Laura Camacho et al.   PLoS One

Upregulated MicroRNA-92b Regulates the Differentiation and Proliferation of EpCAM-Positive Fetal Liver Cells by Targeting C/EBPß

(2013) Nian-Song Qian et al.   PLoS One

Concise Review: The Sox2-Oct4 Connection: Critical Players in a Much Larger Interdependent Network Integrated at Multiple Levels

(2013) Angie Rizzino   STEM CELLS

Sumoylated hnRNPA2B1 controls the sorting of miRNAs into exosomes through binding to specific motifs

(2013) Carolina Villarroya-Beltri et al.   Nature Communications

Human Rhabdomyosarcoma Cell Lines for Rhabdomyosarcoma Research: Utility and Pitfalls

(2013) Ashley R. P. Hinson et al.   Frontiers in Oncology

Exosomes: Current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials

(2012) Alexander V. Vlassov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibition of rhabdomyosarcoma cell and tumor growth by targeting specificity protein (Sp) transcription factors

(2012) Gayathri Chadalapaka et al.   INTERNATIONAL JOURNAL OF CANCER

Comparison of ultracentrifugation, density gradient separation, and immunoaffinity capture methods for isolating human colon cancer cell line LIM1863-derived exosomes

(2012) Bow J. Tauro et al.   METHODS

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Mirna Expression Profiles Identify Drivers in Colorectal and Pancreatic Cancers

(2012) Ada Piepoli et al.   PLoS One

Medulloblastoma Exosome Proteomics Yield Functional Roles for Extracellular Vesicles

(2012) Laura M. Epple et al.   PLoS One

Carboxyamidotriazole-Orotate Inhibits the Growth of Imatinib-Resistant Chronic Myeloid Leukaemia Cells and Modulates Exosomes-Stimulated Angiogenesis

(2012) Chiara Corrado et al.   PLoS One

Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion

(2011) Marco Mineo et al.   ANGIOGENESIS

Identification of nucleotide patterns enriched in secreted RNAs as putative cis-acting elements targeting them to exosome nano-vesicles

(2011) Arsen O Batagov et al.   BMC GENOMICS

Microvesicles Released from Human Renal Cancer Stem Cells Stimulate Angiogenesis and Formation of Lung Premetastatic Niche

(2011) C. Grange et al.   CANCER RESEARCH

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Type I interferon is selectively required by dendritic cells for immune rejection of tumors

(2011) Mark S. Diamond et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Transcriptional Repression of Cdc25B by IER5 Inhibits the Proliferation of Leukemic Progenitor Cells through NF-YB and p300 in Acute Myeloid Leukemia

(2011) Satoki Nakamura et al.   PLoS One

Cancer Exosomes Trigger Fibroblast to Myofibroblast Differentiation

(2010) J. Webber et al.   CANCER RESEARCH

Multiple Roles of Chemokine (C-C Motif) Ligand 2 in Promoting Prostate Cancer Growth

(2010) J. Zhang et al.   JNCI-Journal of the National Cancer Institute

p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment

(2010) R M Hecker et al.   ONCOGENE

Glycogen synthase kinase 3 regulates PAX3–FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells

(2009) Fu-Yue Zeng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line

(2009) EVELYN ARANDA et al.   BIOLOGICAL RESEARCH

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

(2009) Guilherme Rabinowits et al.   Clinical Lung Cancer

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients

(2009) Mariantonia Logozzi et al.   PLoS One

Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice

(2008) A Lespagnol et al.   CELL DEATH AND DIFFERENTIATION

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY